My Rams vs. Cardinals prediction expects rookie quarterback Carson Beck to have a crazy story to tell his kids about his first NFL start... if he survives.
The Arizona Cardinals must march Beck out to face the Los Angeles Rams (-9.5) in Week 10, with both teams shorthanded at wide receiver and the Rams eyeing a much-needed bye in Week 11.
I'm also sorting out the shifting sands in the NFC West, highlighting some of my best NFL picks for Nov. 15.
TOP PICK
Rams vs Cardinals prediction: Under 39.5
This total has dropped a touchdown since opening last Sunday night. And it's not just the Arizona Cardinals' QB quandary dragging the number down.
Both teams will be without their WR1s, as Los Angeles Rams wideout Puka Nacua and Arizona standout Michael Wilson suffered injuries in Week 9.
The cupboard is very bare for Carson Beck, with no Wilson or Kendrick Bourne to throw to, nor does he have RBs Jeremiyah Love and James Conner to help shoulder the offensive load.
As for the Rams, their snake-bitten lineup is looking ahead to a much-needed bye in Week 11. With a spread this size, I expect Los Angeles to try and get up quick and then slow things down in the second half to avoid further casualties.
Los Angeles has seen a significant shift in play calling the past three games, upping its run rate from 36% in the first six outings to 48.5% during this current three-game win streak.
That's slimmed the Rams' yards per play from 5.9 to 5.2 but upped their average time of possession.

Rams vs Cardinals combo
A lack of weapons, a rookie QB, and a Rams team trying to get to the bye week without suffering any more hurt. These are all reasons Arizona and Los Angeles stay below the total in Week 10.
Blake Corum has scored a touchdown in four straight games, including a receiving TD vs. Arizona in Week 6. He'll get a lot of love in the second half, given the big spread and game script.
Tyler Allgeier is now the Cardinals RB1 and is getting a ton of work, with injuries up and down this offense. He's drawn at least three targets in the past three games, and with a rookie QB under center, Allgeier will be a favorite option on short, safe throws.
Rams vs Cardinals combo
- Under 39.5
- Blake Corum anytime touchdown
- Tyler Allgeier 10+ receiving yards
Rams vs Cardinals touchdown scorer: Blake Corum
Blake Corum has enjoyed the Rams' three-game winning streak. He's seen a spike in carries and has struck for a touchdown in each of those outings.
Corum does the bulk of his damage in the second half, providing relief for RB1 Kyren Williams, with four of his five total TDs this season coming in the closing 30 minutes.
His lone first-half strike was a 15-yard touchdown reception in the Week 6 upset loss to Arizona.
Given the beefy spread and the game-script attached to it, Corum will continue to see touches in the final two frames on Sunday. His touchdown forecasts range from 31% to 50% in Week 10.
For more Week 10 touchdown angles, including the Rams D/ST, see our NFL anytime touchdown picks.
Rams vs Cardinals player prop: Tyler Allgeier 10+ receiving yards
With the Cardinals running short on weapons and a rookie quarterback under fire, RB Tyler Allgeier is being asked to do a lot in Week 10.
He took part in 96% of the Cardinals' snaps in Week 9 and has stepped up his role as a receiver during Arizona's QB swap, drawing at least three targets in each of the last three games.
While he didn't record a single gain on two catches in the loss to Seattle last week, Allgeier went for 30 and 44 yards in the two games prior. He caught one of two passes his way for 10 yards against Los Angeles in Week 6.
Beck will use Allgeier as a safety blanket against this big bad Rams pass rush and we'll see some designed passes to the RB early on, in an attempt to get the rookie comfortable with a couple easy completions.
Los Angeles just so happens to allow the most receiving yards to running backs entering Week 10, with 405 yards on 48 receptions – an average of 8.4 yards per catch by rival RBs.
Allgeier's receiving yard outlooks all sit well above 10 yards, with a ceiling of 20 yards. My projection calls for 16.6 receiving yards on Sunday.
Want more NFL player props? Check out our NFL player prop projections!
- Top picks: 13-11, +0.19 units
- Combos: 0-24, -24.0 units
Rams vs Cardinals market trends
Here's how trusted traders at Kalshi are dealing on today's matchup. Follow the smart money via the widget below to help inform your Rams vs. Cardinals prediction.
Rams vs Cardinals odds
For help understanding probabilities, see our odds calculator.
- Spread: Rams -9.5 | Cardinals +9.5
- Over/Under: Over 39.5 (50%) | Under 39.5 (51%)
- Moneyline: Rams 80% | Cardinals 20%
Check the latest NFL odds for more on today's Rams vs. Cardinals matchup.
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Rams vs Cardinals weather
State Farm Stadium has a retractable roof and will open if conditions are nice in Glendale.
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Rams vs Cardinals trend to know
Under Sean McVay, the Rams are 9-1 SU and 6-4 ATS as road favorites of more than a touchdown (since 2017). Find more NFL trends for Rams vs. Cardinals.
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How to watch Rams vs Cardinals
| Location | State Farm Stadium, Glendale, Ariz. |
| Date | Sunday, Nov. 15, 2026 |
| Kickoff | 4:05 p.m. ET |
| TV | FOX |
Rams vs Cardinals latest injuries
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