NFL Week 10 odds kick off at MetLife Stadium for Thursday Night Football as the Washington Commanders battle the New York Giants.
A thrilling Sunday slate wraps up on Sunday Night Football at Paycor Stadium, where the Pittsburgh Steelers take on the division-rival Cincinnati Bengals.
And Monday Night Football heads to M&T Bank Stadium as the Los Angeles Chargers face off against the Baltimore Ravens.
We’re tracking the latest NFL odds, spreads, moneylines, and game totals across the entire Week 10 slate.
NFL odds Week 10
| Matchup | Spread | Moneyline | Over/Under |
|---|---|---|---|
 Commandersvs  Giants |
OTB | 46% 54% |
OTB |
 Patriotsvs  Lions |
OTB | 52% 49% |
OTB |
 Chiefsvs  Falcons |
OTB | 65% 39% |
OTB |
 Texansvs  Browns |
OTB |
64% 40% |
OTB |
 Vikingsvs  Packers |
OTB | 45% 59% |
OTB |
 Jaguarsvs  Titans |
OTB | 82% 17% |
OTB |
 Dolphinsvs  Colts |
OTB | 49% 54% |
OTB |
 Panthersvs  Saints |
OTB | 54% 50% |
OTB |
 Billsvs  Jets |
OTB | 81% 19% |
OTB |
 Seahawksvs  Raiders |
OTB | 68% 32% |
OTB |
 Ramsvs  Cardinals |
OTB | 76% 25% |
OTB |
 49ersvs  Cowboys |
OTB | 66% 37% |
OTB |
 Steelersvs  Bengals |
OTB | 42% 62% |
OTB |
| Chargers vs  Ravens |
OTB | 45% 58% |
OTB |
Lines as of 11-4.
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Thursday Night Football: Commanders vs Giants odds (8:15 p.m. ET, Prime)
Opening line
- Giants — Coming soon!
- Over/Under — Coming soon!
- View full Commanders vs. Giants odds and matchup
- Read our Commanders vs. Giants picks and predictions (coming soon)
Opening line analysis coming soon!
Also see: full Thursday Night Football odds
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Sunday Night Football: Steelers vs Bengals odds (8:20 P.M. ET, NBC)
Opening line
- Bengals — Coming soon!
- Over/Under — Coming soon!
- View full Steelers vs. Bengals odds and matchup
- Read our Steelers vs. Bengals picks and predictions (coming soon)
Opening line analysis coming soon!
Also see: full Sunday Night Football odds
Monday Night Football: Chargers vs Ravens odds (8:15 p.m. ET, ESPN)
Opening line
- Ravens — Coming soon!
- Over/Under — Coming soon!
- View full Chargers vs. Ravens odds and matchup
- Read our Chargers vs. Ravens picks and predictions (coming soon)
Opening line analysis coming soon!
Also see: full Monday Night Football odds
Covers NFL awards analysis
Best NFL bets this week
Looking for our favorite spread, total, and NFL prop bets for this week's action? Check out our best free NFL picks from the Covers staff!
Odds are correct at the time of publishing and are subject to change.
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