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College Football Picks

Free College Football Expert and Computer Picks For Every Game Oct. 25, 2025

Boise State Broncos logo BSU @ Nevada Wolf Pack logo NEV Fri, Oct 24 • 10:00 PM ET
1 Expert Pick 9 Computer Picks
Spread
Boise State Broncos logo BSU -21.5 (-105)
Best Odds
Pick made: 2 days ago
JD Yonke image
JD Yonke
Betting Analyst
Receptions
LC
Latrell Caples u3.5 Receptions (-102)
Projection 3.3853 (Under)
Best Odds
Pick made: 1 hours ago
EV Model Rating
Star rating: 3 out of 5
View 10 Picks
Kansas State Wildcats logo KSU @ Kansas Jayhawks logo KU Sat, Oct 25 • 12:00 PM ET
1 Expert Pick 10 Computer Picks
Rushing Yards
Jalon Daniels logo Jalon Daniels o24.5 Rushing Yards (-114)
Best Odds
Pick made: yesterday
JD Yonke image
JD Yonke
Betting Analyst
Passing Yards
Jalon Daniels logo
Jalon Daniels u240.5 Passing Yards (-114)
Projection 228.0717 (Under)
Best Odds
Pick made: 4 hours ago
EV Model Rating
Star rating: 5 out of 5
View 11 Picks
South Florida Bulls logo USF @ Memphis Tigers logo MEM Sat, Oct 25 • 12:00 PM ET
1 Expert Pick
Spread
Memphis Tigers logo MEM +5.5 (+100)
Best Odds
Pick made: 11 hours ago
Phil Naessens image
Phil Naessens
Betting Analyst

Hill is capable of running the balanced Memphis offense and can put points on the board against a Bulls defense that’s allowed 26 or more points in two of its previous three games.

Memphis is one of the best cover teams in the AAC and can be trusted to cover the spread.

 

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Rutgers Scarlet Knights logo RUTG @ Purdue Boilermakers logo PUR Sat, Oct 25 • 12:00 PM ET
1 Expert Pick
MoneyLine
Purdue Boilermakers logo PUR (+104)
Best Odds
Pick made: yesterday
Jason Ence image
Jason Ence
Betting Analyst

Rutgers has the worst defense of any power conference school in the nation. Oregon just rushed for 400 yards against the Scarlet Knights, scoring touchdowns on seven straight possessions after fumbling it away on the third play of the game.

Purdue moved the ball well against Northwestern but turnovers bit the Boilermakers, as they have many times before. This isn't a game where that should be an issue.

The Purdue defense isn't great, but it's better than what it'll face on Saturday. Regardless of the quarterback, the Boilermakers will move the ball on the ground and get their first conference win of the season at home. 

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UCLA Bruins logo UCLA @ Indiana Hoosiers logo IU Sat, Oct 25 • 12:00 PM ET
1 Expert Pick 10 Computer Picks
Game Prop
Indiana Hoosiers logo o38.5 Team Total (-115)
Best Odds
Pick made: 7 hours ago
Douglas Farmer image
Douglas Farmer
Betting Analyst

Indiana has cleared its Team Total in five of its last six games, falling short only at Iowa, hardly a worrying misstep. The Hoosiers' offense is firing on all cylinders, obviously led by the No. 1 passing offense in the country in terms of expected points added per dropback, per CFB-graphs.com. UCLA's defense has improved immensely in recent weeks, but opponents still know to best attack it through the air. Indiana will be glad to show why.

TD Passes
Fernando Mendoza logo
Fernando Mendoza u2.5 TD Passes (+114)
Projection 2.4331 (Under)
Best Odds
Pick made: 3 days ago
EV Model Rating
Star rating: 3 out of 5
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Northwestern Wildcats logo NW @ Nebraska Cornhuskers logo NEB Sat, Oct 25 • 12:00 PM ET
1 Expert Pick 9 Computer Picks
Receiving Yards
GW Griffin Wilde o51.5 Receiving Yards (-114)
Best Odds
Pick made: yesterday
JD Yonke image
JD Yonke
Betting Analyst

Wilde dominates the Northwestern receiving room like few other receivers do across the country, and this yardage prop is too low given his consistent production.

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Virginia Cavaliers logo UVA @ North Carolina Tar Heels logo UNC Sat, Oct 25 • 12:00 PM ET
1 Expert Pick 8 Computer Picks
Spread
Virginia Cavaliers logo UVA -10.5 (-110)
Best Odds
Pick made: yesterday
Ed Scimia image
Ed Scimia
Betting Analyst

North Carolina faces its toughest test yet in the Bill Belichick era, and there's nothing to suggest that the Tar Heels can even keep it close against Virginia.

View 9 Picks
Mississippi Rebels logo MISS @ Oklahoma Sooners logo OKLA Sat, Oct 25 • 12:00 PM ET
5 Expert Picks 10 Computer Picks
Spread
Oklahoma Sooners logo OKLA -5.5 (-110)
Best Odds
Pick made: yesterday
Douglas Farmer image
Douglas Farmer
Betting Analyst

Oklahoma has the better quarterback, the better defensive, arguably the best defensive line in the country and is at home. The Sooners should be favored by more than a touchdown. There is no need to overthink this.

Score a Touchdown
Trinidad Chambliss logo Trinidad Chambliss Score a Touchdown (Yes: +125)
Best Odds
Pick made: yesterday
Phil Naessens image
Phil Naessens
Betting Analyst

Chambliss has scored a touchdown in each of his last two games, showing clearly he’s a formidable weapon for Mississippi’s offense.


With Oklahoma’s defense as robust as it is, I’m betting Chambliss finds his way into the end zone in this SEC matchup.  

 

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Alabama Crimson Tide logo ALA @ South Carolina Gamecocks logo SOCAR Sat, Oct 25 • 3:30 PM ET
4 Expert Picks 9 Computer Picks
Score a Touchdown
IH Isaiah Horton Score a Touchdown (Yes: +220)
Best Odds
Pick made: yesterday
Ed Scimia image
Ed Scimia
Betting Analyst

Horton isn't getting a lot of catches, but he's doing the most with his opportunities, as he's scored five times already this year.

Game Prop
Alabama Crimson Tide logo o29.5 Team Total (-120)
Best Odds
Pick made: yesterday
Andrew Caley image
Andrew Caley
Senior Betting Analyst

The Crimson Tide are rolling. Pun intended. Bama has won six in a row with QB Ty Simpson looking like a legit Heisman Trophy candidate. Alabama has averaged 31.2 points in its five wins against Power Four teams, and now faces a South Carolina defense that has struggled and ranks 119th in success rate on dropbacks.

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Missouri Tigers logo MIZZ @ Vanderbilt Commodores logo VAN Sat, Oct 25 • 3:30 PM ET
3 Expert Picks 10 Computer Picks
Score a Touchdown
JS Junior Sherrill Score a Touchdown (Yes: +145)
Best Odds
Pick made: yesterday
Ed Scimia image
Ed Scimia
Betting Analyst

Sherrill has six touchdowns this year for the Commodores, and is a great pick to find the endzone again at plus money against LSU.

Total
Missouri Tigers logo Vanderbilt Commodores logo o52.5 (-105)
Best Odds
Pick made: yesterday
Chris Hatfield image
Chris Hatfield
Betting Analyst

These offenses are good. They have clear paths to regularly scoring. The exploits of Vanderbilt QB Diego Pavia are well noted, but the offense has quietly turned into a well-rounded unit. Multiple things can be true. Vandy ranks 4th overall in EPA per rush, and a big part of that is Pavia on the ground. Missouri has done a pretty good job of slowing down QB runs throughout the season. However, they haven’t been great overall at slowing down traditional runs, ranking just 70th nationally in EPA allowed per rush. I think other runners outside of Pavia can have success in this matchup and give Vandy consistent offense.

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Minnesota Golden Gophers logo MINN @ Iowa Hawkeyes logo IOWA Sat, Oct 25 • 3:30 PM ET
1 Expert Pick 6 Computer Picks
Spread
Minnesota Golden Gophers logo MINN +9.0 (-111)
Best Odds
Pick made: 4 days ago
Brad Powers image
Brad Powers
Betting Analyst

It's much more advantageous to take the points than to lay them with a low total (38.5). I haven't been overly impressed with Iowa like the market has. They just beat a team with an interim coach and they beat a Wisconsin team that's gonna have an interim coach in a few weeks.

Passing Yards
MG
Mark Gronowski o140.5 Passing Yards (-114)
Projection 161.5735 (Over)
Best Odds
Pick made: yesterday
EV Model Rating
Star rating: 5 out of 5
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BYU Cougars logo BYU @ Iowa State Cyclones logo ISU Sat, Oct 25 • 3:30 PM ET
2 Expert Picks 10 Computer Picks
MoneyLine
BYU Cougars logo BYU (+120)
Best Odds
Pick made: yesterday
Jason Ence image
Jason Ence
Betting Analyst

BYU is in the final game of a six-week, six-game gauntlet. But I think the Cougars are being discounted too much here.

Iowa State lost to Colorado before the bye week, and struggled with a dual-threat quarterback. Bear Bachmeier will be able to hurt a defense ranked 67th in rush success against and 72nd in third-down success. 

The Cougars are one of the most effective rushing teams in college football, and have a defense that generates a solid havoc rate and limits explosive runs. They also rank Top 20 in third-down rate, against an Iowa State offense ranked 88th in moving the chains. 

I'll take the better team, tired or not, to get the win.

Spread
BYU Cougars logo BYU +2.5 (-104)
Best Odds
Pick made: yesterday
Eric Rosales image
Eric Rosales
Betting Analyst

BYU can defend, allowing 24 points or less in all but one game this season. They rank second in the Big 12 in scoring, allowing 15.6 points per game, while ranking inside the Top 4 in both rush and pass yards against. The Cougars can win outright on the road, and getting those 2.5 points is simply gravy.

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Oklahoma State Cowboys logo OKST @ Texas Tech Red Raiders logo TTU Sat, Oct 25 • 4:00 PM ET
1 Expert Pick
Spread
Oklahoma State Cowboys logo OKST +38.5 (-105)
Best Odds
Pick made: 4 days ago
Douglas Farmer image
Douglas Farmer
Betting Analyst

Texas Tech knows it has no worries against Oklahoma State. The playbook should be treated as such, as vanilla as possible. The Red Raiders will ready for the Cowboys broadly, but not specifically. There is no reason to.

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Baylor Bears logo BAY @ Cincinnati Bearcats logo CIN Sat, Oct 25 • 4:00 PM ET
1 Expert Pick 10 Computer Picks
Spread
Cincinnati Bearcats logo CIN -5.5 (-110)
Best Odds
Pick made: 4 days ago
Douglas Farmer image
Douglas Farmer
Betting Analyst

Cincinnati's trenches are underappreciated. This Baylor defense just gave up 42 points to TCU. The Bears' defensive woes are too many to slow the Bearcats, and without slowing them, it may be a long night.

Passing Yards
SR
Sawyer Robertson u312.5 Passing Yards (-114)
Projection 284.9498 (Under)
Best Odds
Pick made: 7 hours ago
EV Model Rating
Star rating: 5 out of 5
View 11 Picks
Texas Longhorns logo TEX @ Mississippi State Bulldogs logo MSST Sat, Oct 25 • 4:15 PM ET
2 Expert Picks 9 Computer Picks
Game Prop
Texas Longhorns logo u27.5 Team Total (-125)
Best Odds
Pick made: 20 hours ago
Jason Ence image
Jason Ence
Betting Analyst

Arch Manning hasn't handled road environments very well. He led just three scoring drives at Florida in 13 possessions, and should've lost at Kentucky last week as he completed just 12 of 27 passes.

He's facing a Mississippi State defense that ranks sixth in interceptions, and seventh in interception rate against. The Bulldogs also love to run the ball, which should shorten the number of possessions available to both teams.

Texas will need to run the ball to help Manning, but the Longhorns rank 116th in late-down success, 105th in available yards, and 110th in EPA/pass. And the Longhorns have not scored 24 points in four games against power conference foes.

Manning will struggle with the incessant cowbell ringing and Texas will not get to 28 points.

MoneyLine
Mississippi State Bulldogs logo MSST (+220)
Best Odds
Pick made: yesterday
Jason Ence image
Jason Ence
Betting Analyst

Unlike Bruce Dickinson, the last thing Arch Manning needs is more cowbell. But the Mississippi State faithful are gonna give him all he can handle. 

Manning routinely missed wide-open throws against a Kentucky secondary that has given up big pass plays often this season. And he's looked rattled in both of his SEC road starts.

The Bulldogs have the best rushing success rate of any team in the nation, and they've nearly gotten that "big" win against both Florida and Tennessee. They fell just short over the weekend, but the cowbells will get to Manning and they'll get the win on Saturday. 

 

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Stanford Cardinal logo STAN @ Miami (FL) Hurricanes logo MIA Sat, Oct 25 • 7:00 PM ET
2 Expert Picks 8 Computer Picks
Spread
Stanford Cardinal logo STAN +29.5 (-110)
Best Odds
Pick made: 9 hours ago
Eric Rosales image
Eric Rosales
Betting Analyst

Stanford is third in the conference in time of possession. If they can sustain a few drives and come away with touchdowns, with that deep bag of points given, they should be able to stay within earshot of the Hurricanes.

Receiving Yards
CW CJ Williams o41.5 Receiving Yards (-114)
Best Odds
Pick made: 12 hours ago
JD Yonke image
JD Yonke
Betting Analyst
View 10 Picks
Texas A&M Aggies logo TAM @ LSU Tigers logo LSU Sat, Oct 25 • 7:30 PM ET
4 Expert Picks 10 Computer Picks
Score a Touchdown
MR Marcel Reed Score a Touchdown (Yes: +160)
Best Odds
Pick made: yesterday
Ed Scimia image
Ed Scimia
Betting Analyst

Reed will need to use his legs as much as his arm to help Texas A&M beat LSU, which has me backing him to add to his touchdown total.

Spread
Texas A&M Aggies logo TAM -2.5 (-115)
Best Odds
Pick made: yesterday
Douglas Farmer image
Douglas Farmer
Betting Analyst

Could LSU still make the Playoff? Absolutely. But the writing is on the wall: The Tigers went all-in on the 2025 season and are going to fall short of all their goals. This locker room may be on the verge of discord following last week's humbling loss at Vanderbilt. Texas A&M is not who you want to face when already stumbling. The Aggies should bludgeon the Tigers into submission this week, led by a defense that excels in late-down situations, a strength that could exacerbate LSU's surprising offensive struggles.

View 14 Picks
Michigan Wolverines logo MICH @ Michigan State Spartans logo MSU Sat, Oct 25 • 7:30 PM ET
3 Expert Picks 10 Computer Picks
Rushing Yards
BU Bryce Underwood o16.5 Rushing Yards (-114)
Best Odds
Pick made: 12 hours ago
JD Yonke image
JD Yonke
Betting Analyst

Underwood averaged 28.9 rushing yards per game, so his prop of 16.5 rushing yards stands out as a discount. The Spartans have a very poor defense overall (128th in success rate allowed) and struggle against the run (111th in rushing success rate), primarily due to a soft defensive front (133rd in power success rate). 

Rushing Yards
BU Bryce Underwood o16.5 Rushing Yards (-114)
Best Odds
Pick made: yesterday
Jeremy Jones image
Jeremy Jones
Betting Analyst

True freshman quarterback Bryce Underwood has had a few growing pains this season, but there is no denying his raw talent. He is also an incredible athlete and can make huge plays in the running game when the coaching staff allows him to do so. Michigan State ranks in the bottom half of the country in team sacks. If they are unable to get sacks on Bryce Underwood, then he should not need to take off too often to easily hit this number. There will be plenty of pass plays for Michigan in this game and I think he scrambles a few times to get this even if he gets no designed runs.

View 13 Picks
Colorado Buffaloes logo COLO @ Utah Utes logo UTAH Sat, Oct 25 • 10:15 PM ET
2 Expert Picks 10 Computer Picks
Receiving Yards
OM Omarion Miller o37.5 Receiving Yards (-115)
Best Odds
Pick made: 12 hours ago
JD Yonke image
JD Yonke
Betting Analyst

Miller has gone Over this number in five of his last six. He is averaging an eye-popping 18.6 yards per reception and possesses the requisite size and athleticism to keep Utah’s corners honest. 

 

Spread
Colorado Buffaloes logo COLO +13.5 (-112)
Best Odds
Pick made: yesterday
JD Yonke image
JD Yonke
Betting Analyst

There are few players as integral to their team’s success as Devon Dampier. I can’t comfortably say that the Utes will win this game by two scores with him hobbled.

View 12 Picks

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