Los Angeles Rams Preview: Odds, Picks & Predictions for the 2025-26 Season

Matthew Stafford and Puka Nacua could form a dangerous one-two punch against the NFC West, but concerns about health cast doubt on how much success the Rams can achieve this season as Jason Logan explains.

Jason Logan: Senior Betting Analyst at Covers
Jason Logan • Senior Betting Analyst
Aug 27, 2025 • 13:51 ET • 4 min read
Puka Nacua Los Angeles Rams NFL
Photo By - Imagn Images. Los Angeles Rams wide receiver Puka Nacua (17) carries the ball.

The Los Angeles Rams were a perfect example of a team that got hot late in the season and rode that momentum into the playoffs. 

The Rams stumbled out of the blocks with an inconsistent 4-5 SU start (3-6 ATS) but this young roster found its footing in the back half of the schedule. 

Los Angeles won six of the final eight outings (including sitting the starters in a Week 18 loss) and nearly flipped the NFC postseason on its ear, beating Minnesota and taking Philadelphia to the limit.

All the ingredients remain in 2025. Sean McVay is the best coach in the NFL. Matthew Stafford is better than the bulk of quarterbacks. And L.A.’s defensive line will win the neutral zone war most snaps.

The oddsmakers like what they see in Los Angeles. The win total is shaded toward 10 victories, the division odds are right on the heels of San Francisco, and look-ahead lines give the Rams the nod in 13 games.

So why I am I hesitant to buy into L.A.?

Let’s explore those apprehensions in my 2025 Los Angeles Rams 2025 NFL betting preview.

Los Angeles Rams best bets

Pick bet365
Make Playoffs -165
Puka Nacua Over 5.5 Receiving Touchdowns -140

Read on for Jason's full analysis and Los Angeles Rams breakdown! 

Los Angeles Rams odds for 2025

Market bet365
Win Super Bowl +2000
Win conference +1000
Win division +180
Make playoffs -165
Over 9.5 wins -145
Under 9.5 wins +115

Best futures bet: Make playoffs (-165)

So much of the Los Angeles Rams' success is tied to health. And not just their own.

The durability of the 49ers has a major say in how this division trickles down. If San Francisco’s stars stay upright, the NFC West is a frickin’ dog fight. Seattle and Arizona aren’t pushovers by any means, either.

The status of Stafford’s spine is another major concern for L.A. backers. The 39-year-old is on track to play Week 1 but is one hard hit away from missing time. Blood clots issues for top offensive lineman Alaric Jackson compounds that problem.

I have the Rams making a run at a Wild Card spot, needing at least 10 wins to punch that dance card. I’m down on Green Bay and don’t see Atlanta, Seattle, or Chicago making the postseason cut.

Los Angeles Rams at a glance: As strong as Stafford

Stafford was limited this summer due to back pain and just started practicing the past two weeks, reportedly needing an epidural to manage discomfort of a damaged disc. 

As a former athlete who played through severe back issues, my sciatica flares up just looking at Los Angeles’ start to the schedule.

The team plays four of six away from home between Week 2 and a Week 7 trip to London. And knowing the way McVay operates, he’ll likely keep the team on the East Coast after a Week 6 game at Baltimore before crossing the pond. 

That’s a lot of extended sitting and sleeping away from your own bed. And that’s before a 300-pound lineman body slams you.

What will win bets: Defensive line

The maturation of this young defense was something to watch in 2025, especially the play of Jared Verse, Braden Fiske, Jobie Turner, and Byron Young up front. 

The Rams were able to dial up pressure, hurry rival QBs, and were extremely stingy in the red zone (fourth lowest TD% allowed). Taking the next step would push L.A. over the top. 

After lacking “game changing” plays in the regular season, Los Angeles’ pressure scored 16 sacks in the two playoff games, including two takeaways in the Wild Card win over Minnesota.

What will lose bets: Stafford’s back

The Rams are putting a lot of faith in the offensive line, which rates out in the top half of the league. Los Angeles can’t afford any extra wear and tear on Stafford’s spine, which may be inevitable considering the opening schedule.

On top of the travel concerns mentioned above, L.A. faces a few vaunted defenses and aggressive pass rushes, starting with Houston in Week 1. Philadelphia and Baltimore also take aim at the 39-year-old QB before the Week 8 bye.

To me, it’s not a matter of “if” Stafford misses time but rather “when”.

Los Angeles Rams schedule + spot bet: Road rash sandwich

Los Angeles has a home-friendly run between Week 9 and Week 12 sandwiched between two tough patches. In fact, added up, the Rams log the second most miles of any NFL team this season.

After starting at home versus Houston in Week 1, L.A. will play four of the next six games away from SoFi Stadium thanks to a UK appearance versus Jacksonville in Week 7. A heavy travel slate shows up between Week 13 and Week 17, with four of five games on the road.

Since Stafford arrived in 2021, Los Angeles is 18-16 SU and 16-15-3 ATS as a visitor in the regular season. That includes a 5-3 SU and ATS road record last year.

Spot bet: Week 16 at Seattle (TNF) -1.5, 44.5

The Rams travel to the Emerald City on a short week in mid-December, still licking their wounds from a huge game the week before.

A letdown spot stares McVay & Co. in the face at Seattle, following a showdown with Detroit in Week 15 – a game that could hold a lot of weight in the NFC postseason picture. That leaves very little time to rest, prep and travel for this Thursday night affair.

Not only that but poor weather in the Pacific Northwest could be waiting for the Rams, who will be playing just their second outdoor game in the final eight weeks of the schedule. Stafford’s stats slide outdoors, especially in inclement weather.

Plenty of points from Puca

Market bet365
Lead NFL in Receiving Yards +1100
Win Offensive Player of the Year +1600
Over 1200.5 Receiving Yards -110
Under 1200.5 Receiving Yards -110
Over 5.5 Receiving Touchdowns -140
Under 5.5 Receiving Touchdowns +110

Puka Nacua best bet: Over 5.5 Receiving Touchdowns (-140)

An injury in Week 1 made it tough for Nacua to build on his sensational rookie season. He caught only three touchdowns after scoring six in 2023.

In 2025, he’s no longer sharing red-zone targets with Cooper Kupp and is undoubtedly Stafford’s first option. The Rams’ schedule features more than a few sad-ass secondaries for Puka to exploit.

Season-long models aren’t bullish on Nacua’s touchdown output, with models sitting between six and seven scores. As long as Stafford is standing, he’s a threat to find the end zone.

Los Angeles Rams trend: Divisional Road Games

The NFC West will be a slog for all four teams. Luckily McVay knows how to steal a coveted win in enemy territory. Or at least cover the spread.

Since he took over in 2017, the Rams are 16-8 SU and 17-7 ATS in divisional road games. That includes an 8-4 SU count and 9-3 ATS windfall since Stafford showed up in 2021.

Los Angeles Rams divisional road games

  • Week 10 at San Francisco +1.5
  • Week 14 at Arizona -1.5
  • Week 16 at Seattle (TNF) -1.5

More NFL team previews

Want to see Jason's forecast for the rest of the NFL? Check out all of his NFL team previews below!

Odds are correct at the time of publishing and are subject to change.
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Jason Logan Senior Industry Analyst Covers.com
Senior Betting Analyst

In his 20 years with Covers, lead NFL betting analyst; has seen it all and bet it all. Through the wild west of early Internet gambling to lobbying for legalized sports betting to our brave new wagering world, Jason has been a consistent source of actionable info and entertainment for squares and sharps alike. Since joining the Covers team back in 2005, he honed his handicapping skills to provide audiences with the most thorough insights, blending traditional capping methods with advanced modelling and predictive analysis. Jason has studied the ins and outs of the sports betting business, learning from some of the most successful gamblers in the industry and the biggest sportsbook operators on the planet. He is under center for Covers during NFL season as our top NFL expert, taking the points in his infamous NFL Underdogs column and representing the Covers Community at the Super Bowl. While he lives for football season, Jasons first love is basketball and that shows in his in-depth NBA, NCAA, and WNBA betting breakdowns. On top of being a mainstay in media from coast to coast; WPIX, PHL17, Fox 5 San Diego, WGNO, TSN, SportsNet, ESPN Radio; he had his analysis featured in USA Today, MSNBC, ESPN, the Wall Street Journal, CBS, Bloomberg, the L.A. Times, the New York Times and other major publications. You can also find JLo stuffing all the top picks and predictions he can into 10 minutes as the host of Covers; flagship podcast, The Sharp 600.

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