Week 8 odds saw plenty of tricks as we expected heading into the week, including a scary performance from Patrick Mahomes against the Denver Broncos.
NFL odds come to a close when the Las Vegas Raiders roll into Motown to match up with the Detroit Lions on Monday night to wrap up a spooky pre-Halloween week in NFL betting action.
Here's a look at the opening NFL Week 8 odds as well as early adjustments for the final match on the slate before we head into Week 9.
NFL Week 8 odds, lines, and spreads
These are the live NFL odds for Week 8, highlighting the best odds available from regulated sportsbooks within your area.
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Buccaneers vs. Bills odds
Opening line
- Bills -8
- Over/Under 42.5
- View full Buccaneers vs. Bills line movement
- Read our Buccaneers vs. Bills picks and predictions
The Bills don't have to wait long to rid of the taste of an upset loss to New England, getting the Bucs at home on Thursday Night Football. Buffalo opened as big as an 8-point favorite but that spread has slipped to -7.5 at some shops on Sunday night.
Also see: full Thursday Night Football odds
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Texans vs. Panthers odds
Opening line
- Panthers +3
- Over/Under 41.5
- View full Texans vs. Panthers line movement
- Read our Texans vs. Panthers picks and predictions
Both sides enjoyed a bye in Week 7 but only the Texans are likely looking forward to the rest of the season. Houston opened as a 3-point road favorite in Carolina — just the fourth time the Texans have laid the points on the road since 2019. The Panthers desperately needed the bye with injuries on both sides of the ball.
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Rams vs. Cowboys odds
Opening line
- Cowboys -5.5
- Over/Under 45.5
- View full Rams vs. Cowboys line movement
- Read our Rams vs. Cowboys picks and predictions
Dallas was off this past week after winning a dud of a game vs. the other L.A. team in Week 6. The Rams lost a grinder against the Steelers this past weekend and opened as low as +5.5 before money pushed this spread as far as +6.5 at some sportsbooks.
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Vikings vs. Packers odds
Opening line
- Packers -1
- Over/Under 43
- View full Vikings vs. Packers line movement
- Read our Vikings vs. Packers picks and predictions
The Vikings are coming off a really nice win on Monday Night Football, while the Packers' struggles continued in Week 7 with a 19-17 loss to the Denver Broncos. Oddsmakers opened the Packers as 1-point home favorites for this Sunday afternoon NFC North showdown. The total hit betting boards at 43.
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Saints vs. Colts odds
Opening line
- Colts -1.5
- Over/Under 41.5
- View full Saints vs. Colts line movement
- Read our Saints vs. Colts picks and predictions
The look-ahead line has the Colts getting +1.5 but after the Saints' loss to Jacksonville last Thursday and Indianapolis taking the best defense in the league to the limit, this official Week 8 opener hit the board with the Colts at -1.5. Early play on the Over has moved this total as high as 42.5 points.
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Patriots vs. Dolphins odds
Opening line
- Dolphins -10.5
- Over/Under 47
- View full Patriots vs. Dolphins line movement
- Read our Patriots vs. Dolphins picks and predictions
The Dolphins looked mediocre in a 31-17 loss to the Philadelphia Eagles on Sunday Night Football, while the Patriots pulled off a shocking 29-25 win over the visiting Buffalo Bills in Week 7. Can the Pats build off that big win last week? Oddsmakers don't think so, with the Dolphins opening as big 10.5-point home favorites and an opening total of 47.
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Jets vs. Giants odds
Opening line
- Giants +3
- Over/Under 36
- View full Jets vs. Giants line movement
- Read our Jets vs. Giants picks and predictions
The Jets enjoyed a much-needed bye after a whirlwind start to the season and the Giants snapped their losing skid with an inspired effort against Washington at home in Week 7. Quarterback Daniel Jones is still questionable with a neck injury, setting up a possible QB controversy for this Battle of the Big Apple. The Jets opened -3 but could be moving to -3.5 with vig stacking up on the favorite.
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Jaguars vs. Steelers odds
Opening line
- Steelers +1.5
- Over/Under 41.5
- View full Jaguars vs. Steelers line movement
- Read our Jaguars vs. Steelers picks and predictions
This matchup opened with Jacksonville as short as a 1-point favorite at most books but didn't take long to move as high as -2 on Sunday night. The Jaguars have looked strong on both sides of the ball during their four-game winning streak while the Steelers are the ugliest 4-2 team in the NFL... maybe ever.
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Falcons vs. Titans odds
Opening line
- Titans +1
- Over/Under 37
- View full Falcons vs. Titans line movement
- Read our Falcons vs. Titans picks and predictions
Tennessee is coming off a bye and it sounds like QB1 Ryan Tannehill is out for this Week 8 date. That would leave backup Malik Willis under center against a stingy Falcons defense. Atlanta squeaked out a win over rival Tampa Bay this past weekend and opened as a 1-point road favorite. The look-ahead total was 38.5 points but this number has slid to as low as 37 points on Sunday night.
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Eagles vs. Commanders odds
Opening line
- Commanders +6.5
- Over/Under 44.5
- View full Eagles vs. Commanders line movement
- Read our Eagles vs. Commanders picks and predictions
The Eagles throttled the visiting Miami Dolphins, 31-17, on Sunday Night Football, while the struggling Commanders lost a 14-7 snooze-fest to the New York Giants in Week 7. Oddsmakers opened with the Eagles tabbed as 6.5-point road favorites and the opening total was set at 44.5.
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Browns vs. Seahawks odds
Opening line
- Seahawks -2
- Over/Under 41
- View full Browns vs. Seahawks line movement
- Read our Browns vs. Seahawks picks and predictions
The health of Browns QB Deshaun Watson is once again giving bookies and bettors a headache, as he left Week 7 with a concussion and didn't return despite reportedly being clear to continue. This game is sitting between Seattle -2 and -3 across the industry, with those books opening at -2 and quickly moving up to -2.5.
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Ravens vs. Cardinals odds
Opening line
- Cardinals +9
- Over/Under 45.5
- View full Ravens vs. Cardinals line movement
- Read our Ravens vs. Cardinals picks and predictions
The look-ahead line was Ravens -7.5 but after Baltimore bashed the Lions this past weekend, the official Week 8 opener sees Lamar & Co. laying -9 on the road. This spread is bouncing between -8 and -10 on Sunday night while the total opened as big as 45.5 before sharply dropping to 44 points.
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Chiefs vs. Broncos odds
Opening line
- Broncos +8.5
- Over/Under 45.5
- View full Chiefs vs. Broncos line movement
- Read our Chiefs vs. Broncos picks and predictions
These AFC West rivals played two weeks ago, with the Chiefs grinding out a 19-8 win to cover as 10.5-point home chalk. The Week 8 rematch in Colorado has the Broncos getting +8.5 with the total jumping from 45.5 to 46 points on Sunday night.
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Bengals vs. 49ers odds
Opening line
- 49ers -6
- Over/Under 46
- View full Bengals vs. 49ers line movement
- Read our Bengals vs. 49ers picks and predictions
The 49ers come into this Week 8 matchup off two consecutive losses, and welcome a Bengals side that is coming off a bye and seemingly healthy after a slow start to the season. This afternoon game shapes up as one of the highlights of the Week 8 schedule and opened with the Niners tabbed as 6-point home favorites. The total hit betting boards at 46.
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Bears vs. Chargers odds
Opening line
- Chargers -9
- Over/Under 44
- View full Bears vs. Chargers line movement
- Read our Bears vs. Chargers picks and predictions
Los Angeles is laying nine points at home to Chicago and likely backup QB Tyson Bagent, who played well in relief of the injured Justin Fields in Sunday's win over the Raiders. The Chargers are coming off a bad loss at Arrowhead vs. the Chiefs, once again unable to stop their opponent from scoring. This total opened at 44 points and is now as high as 45 on Sunday night.
Also see: full Sunday Night Football odds
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Raiders vs. Lions odds
Opening line
- Lions -7.5
- Over/Under 45
- View full Raiders vs. Lions line movement
- Read our Raiders vs. Lions picks and predictions
The Monday Night Football finale has the Lions licking their wounds off a one-sided beatdown from Baltimore in Week 7, laying -7.5 to the visiting Raiders. Las Vegas will have QB1 Jimmy Garoppolo back under center for Week 8 after suffering a bad loss in Chicago with backup Brian Hoyer running the offense.
Also see: full Monday Night Football odds
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Best NFL bets this week
Looking for our favorite spread, total, and NFL prop bets for this week's action? Check out our best free NFL picks from the Covers staff!
More weekly NFL odds content
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