NFL Week 6 Odds and Betting Lines: Bolts Have Seen Spread Drop From -6.5 to -4.5

9:00 A.M. ET, THURSDAY, OCT. 13: Despite injuries to the 49ers defense taking this spread from San Francisco -6 to as low as -5, midweek money has shown up on the favorite and moved this spread back to Niners -6. Atlanta is expected to have Drake London and Kyle Pitts on offense, which has ticked this total up to 44.5 points.

9:30 A.M. ET, WEDNESDAY, OCT. 12: With injuries across the defense for the 49ers, this line that line climbed as high as San Francisco -6.5 is down as low as -5 at some books. DraftKings is reporting 77% of bets and 73% of handle on the Niners. The total sits between 43.5 and 44.5 points.

10:00 P.M. SUNDAY, OCT. 9: The 5-0 ATS Falcons opened as low as +5.5 for this run-in with the 49ers and early action is on red-hot San Francisco, pushing this spread to Niners -6. The total opened at 42.5 points.

9:00 A.M. ET, THURSDAY, OCT. 13: The Browns have injuries to key stars on defense, including CB Denzel Ward and DE Myles Garrett. Over in New England, QB Mac Jones was limited in practice as he works his way back from the ankle injury and is listed as questionable for Sunday. That has this spread down from Cleveland -3 to -2.5 and the total at 43.5 points. PointsBet books are reporting 62% of bets and 63% of money on the visiting Patriots.

10:00 P.M. SUNDAY, OCT. 9: Cleveland opened -2.5 hosting the Patriots in Week 6. Despite a tough loss at home to the Chargers on Sunday and the Patriots plowing through the Lions, some books are up as high as Browns -3. The Over/Under opened at 42 and is up to 42.5 points.

9:00 A.M. ET, THURSDAY, OCT. 13: Rumblings of a banged-up thumb for Packers QB Aaron Rodgers has moved this line, with Green Bay as low as a -7 with heavy vig and the total is sitting as low as 45 points after climbing as high as 47 earlier in the week. PointsBet books are reporting 57% of bets on the Jets and a heavy 75% of handle on New York.

12:15 P.M. MONDAY, OCT. 10: Sharps and some well-respected betting groups hit the Over on this game Sunday night, forcing books to move their Over/Under from 44.5 to 47. As of Monday morning, the pointspread is still hanging on at Packers -7.5.

10:00 P.M. SUNDAY, OCT. 9: Despite the Packers coming off a loss to the Giants in London on Sunday, the Cheeseheads return home as 7.5-point chalk. Early money has sided with Green Bay, bumping this spread to as high as -8 in the face of the Jets winning back-to-back games and two of their last three. The total opened at 45 points and is down to 44.5.

2:57 P.M. ET, SATURDAY, OCT. 15: On Saturday afternoon, Colts RBs Jonathan Taylor and Nyheim Hines were both downgraded to Out for Sunday's game at home against the Jaguars. The point spread shortened from Colts -2.5 to -1.5 and the total dropped a point from 42 to 41.

9:45 A.M. ET, WEDNESDAY, OCT. 12: Pro betting groups grabbed Indianapolis -1.5 and have forced books to adjust this AFC South showdown to Colts -2.5. According to DraftKings books, 51% of bets on the Jaguars but 70% of money on the home side. This total is sitting between 41.5 and 42.5 points.

10:00 P.M. SUNDAY, OCT. 9: Indianapolis has had a mini bye since squeaking out an ugly win last Thursday and opened as 1.5-point home chalk to Jacksonville in Week 6. The Jaguars have dropped back-to-back games and haven’t looked like the team that shut out the Colts back in Week 3. The status of Indianapolis RB Jonathan Taylor will have an impact on this line as the week progresses.

9:00 A.M. ET, THURSDAY, OCT. 13: Neither Tua Tagovailoa nor Teddy Bridgewater will be clear of the NFL’s new concussion protocols by kickoff on Sunday, leaving third-stringer Skylar Thompson as Miami’s starting QB in Week 6. That bumped this spread from Vikings -3 to as high as -4 while the total took a dive down as low as 45.5 points. The Dolphins also have RB Raheem Mostert and WR Tyreek Hill listed as questionable for Sunday.

12:15 P.M. MONDAY, OCT. 10: Books delayed opening with numbers for this Sunday matchup between the Minnesota Vikings and the host Miami Dolphins. There is plenty of uncertainty surrounding Miami's quarterback situation with both Tua Tagovailoa and Teddy Bridgewater questionable with concussion issues. Betting numbers finally hit the board late Sunday night with a point spread anywhere from Vikings -2.5 to -3.5 and a total of 45/45.5. Expect plenty of movement this week as more news becomes available.

1:16 P.M. TUESDAY, OCT. 11: After opening at Bengals -1, the point spread for this Sunday afternoon content lengthened slightly to Bengals -2 on Tuesday. The total dropped slightly and is now at 43.5 across most respected books

12:15 P.M. MONDAY, OCT. 10: The Bengals dropped a tough 19-17 decision in Baltimore against the Ravens on Sunday Night Football and opened as 1-point favorites for Sunday's second-consecutive road game. The host Saints rode a huge offensive day from Taysom Hill to a 39-32 win over the Seahawks. The total opened at 44.

9:30 A.M. ET, THURSDAY, OCT. 13: Betting markets aren't overly sold on the 4-1 Giants and have moved this spread from Ravens -5 to -6. According to PointsBet books, 61% of bets and 73% of the handle is on Baltimore. This total is sitting between 44.5 and 45 points.

12:15 P.M. MONDAY, OCT. 10: The surprising Giants opened as 5-point home underdogs coming off their shocking 27-22 win over the Packers in London. The visiting Ravens dumped the Bengals 19-17 on Sunday Night Football and sit at the top of the AFC North standings at 3-2. The total for Sunday's game at MetLife Stadium opened at 43.5.

2:49 P.M. ET, SATURDAY, OCT. 15: The Steelers' secondary will be incredibly thin for Sunday's game at home against Tom Brady and the Tampa Bay Buccaneers. Star safety Minkah Fitzpatrick in addition to CBs Ahkello Witherspoon, Can Sutton, and Levi Wallace were all ruled out late Friday. Books were quick to adjust the betting numbers, bumping the point spread from Bucs -8.5 to -10 and the total from 45.5 to 46.

1:53 P.M. ET, FRIDAY, OCT. 14: After bumping up from Buccaneers -7.5/-8 to -8.5 at some shops, the point spread for this Sunday matchup went to -8.5 universally across all respected books Friday. The total took a sharp jump from 44 to 45.5 with respected money coming in on the Over.

9:45 A.M. ET, WEDNESDAY, OCT. 12: Money on the Buccaneers has shown up early in the week, pumping this spread to Tampa Bay -8.5 at some shops. DraftKings books are reporting 80% of bets and 85% of handle on the Bucs. The total is sitting as high as 44 points.

10:00 P.M. SUNDAY, OCT. 9: After getting boat-raced out of Buffalo on Sunday, the Steelers are back home and opened as 7.5-point underdogs hosting Tampa Bay in Week 6. That line has climbed as high as Buccaneers -8 at some sportsbooks while the total is down to 42.5 points. 

9:30 A.M. ET, THURSDAY, OCT. 13: After this spread climbed to Rams -11, in the wake of the Baker Mayfield injury and Matt Rhule firing, sharp players bought back Carolina at the inflated spread and that brought the line back down as low as Los Angeles -9.5. PointsBet books are reporting 64% of bets and 83% of the handle riding with the Panthers in Week 6.

1:22 P.M. MONDAY, OCT. 10: It was announced Monday afternoon that Baker Mayfield has a high-ankle sprain and will miss Sunday's game in Los Angeles against the Rams. Some people may think this is a good thing for the struggling Panthers, but books adjusted the point spread to Rams -11 and edged the total down from 41.5 to 40.5. Former XFL star P.J. Walker will get the start in place of Mayfield.

10:00 P.M. SUNDAY, OCT. 9: Los Angeles has dropped back-to-back games but stays home to host the floundering Panthers in Week 6. Carolina QB Baker Mayfield was wearing a walking boot on his left foot after the loss to San Francisco, which could have third-stringer P.J. Walker potentially playing on the road vs. the Rams defense. This total is sitting at 41.5 points.

9:45 A.M. ET, WEDNESDAY, OCT. 12: Seattle has slid from +2.5 to +3 at some operators, with an early interest in Arizona. DraftKings sportsbooks are reporting 65% of bets and 73% of money backing the visiting Cardinals. This total has climbed from 50 points to as high as 51.5.

10:00 P.M. SUNDAY, OCT. 9: This NFC West war has the potential to be a fun one if the Seahawks keep slinging the football. Arizona opened as 2.5-point road chalk and that spread is as low as -2. It’s the total, however, that is the most interesting number. This opened at 50.5 and is now as high as 51.5 points on Sunday night.

9:30 A.M. ET, THURSDAY, OCT. 13: Action on this marquee matchup has bounced back and forth in the first part of the week, with Buffalo sitting between -2.5 and -3 across the industry. According to PointsBet books, 52% of bets and 67% of handle is backing the host Chiefs. This total has climbed from an opener of 54 points to as high as 55 at some Vegas-based books. PointsBet is reporting one-side play on the Over, which has drawn 90% of bets and 91% of the handle.

1:23 P.M. TUESDAY, OCT. 11: The Chiefs fell behind early, but rode the Mahomes-to-Kelce wave to an impressive 30-29 victory over the Raiders on Monday Night Football in Week 5. Next up is a rematch of last season's thrilling Divisional Playoff contest, with the Buffalo Bills coming to town for Week 6. The Bills opened as 1.5-point road favorites and as of Tuesday morning that number has lengthened to Buffalo -2.5. The total opened at 54 and if the last few meetings between these two teams are any indication, that number may not be high enough.

9:30 A.M. ET, THURSDAY, OCT. 13: Midweek money showed up on Philadelphia on Wednesday with positive injury news coming out about the Eagles’ dinged-up offensive line. That pumped this spread from Philly -5 to -6.5 at some operators. PointsBet books are reporting 64% of bets on Dallas but the handle is more even with just 54% of money siding with the visitor.

9:45 A.M. ET, WEDNESDAY, OCT. 12: While some books are down to -5, many spots are back to Eagles -6 for Sunday Night Football. DraftKings, which is dealing Philly -6, is reporting a notable split for this NFC East rivalry, with 61% of bets backing the Cowboys but 60% of the handle on the Eagles. The total has slimmed from 43.5 points to as low as 42.

10:30 P.M. SUNDAY, OCT. 9: The Eagles remain undefeated but face their toughest test at home in Week 6. Philadelphia opened -5.5 hosting the Cowboys in a pivotal NFC East contest and some books are down to -5 with early play on Dallas. This total opened at 43.5 points and is down to 43 at one respected online book.

1:00 P.M. ET, MONDAY OCT. 17: Monday Night Football gives the Denver Broncos another primetime matchup, but this time against the Los Angeles Chargers. L.A. is laying -4.5 at most books but can be found at -4 for a little extra cost. Keenan Allen is still doubtful, and Denver also has a laundry list of injuries. DraftKings is reporting 77% of bets on Chargers -4 with 67% of money leaning that way. On the total front, Under 46 is drawing 71% of bets and 70% of handle.

9:00 A.M. ET, SUNDAY OCT. 16: Monday Night Football sees the AFC West on the big stage for the second week in a row. This time the Chargers are laying -4.5 to the visiting Broncos. Los Angeles isn’t expected to have WR Keenan Allen for Week 6 but is getting healthier than the past few weeks. Denver, on the other hand, has a long list of injuries heading into the Monday finale. BetMGM books are reporting 67% of bets and 60% of money on the Bolts. 

9:45 A.M. ET, WEDNESDAY, OCT. 12: With Russell Wilson expected to play on Monday after getting treatment on his torn lat, this spread is down to as low as Chargers -4.5 at respected online books. DraftKings is reporting 75% of early bets and 63% of the money on Los Angeles. The total is sitting at 45.5 points. 

10:30 P.M. SUNDAY, OCT. 9: The AFC West headlines the Week 6 finale on Monday Night Football, with Los Angeles opening at -6. Early opinion is varied, with some shops down to Bolts -5.5 and others dealing L.A. -6.5. The Broncos have had a mini-bye after losing a gross game on Thursday and QB Russell Wilson is battling a torn lat muscle. This total has climbed from 45.5 to 46.5 at some operators on Sunday night.