Want to celebrate your holidays with the NFL? Well, you don't have much say in the matter, as the league's Week 16 schedule for the 2022 season features the full slate on Saturday, December 24, and three games on Christmas Day.
Helping you get in the spirit on Dec. 25 is a trio of great games and legendary quarterbacks, with Packers and Dolphins kicking things off, followed by the Broncos and Rams in L.A., and coming to a close with the Bucs visiting Arizona to face the Cardinals.
Here is the list of all the latest NFL Week 16 odds, times, and spreads.
NFL Week 16 Odds
These are the NFL odds for Week 16, headlined by a full three-game slate on Christmas Day, with Tom Brady and the Bucs visiting Kyler Murray and the Cardinals.
| Matchup | Time | Spread | Over/Under |
|---|---|---|---|
| Jaguars at Jets | Thurs, 8:20 p.m. ET | Jets -2.5 | OTB |
| Falcons at Ravens | Sat, 1 p.m. ET | Ravens -7.5 | OTB |
| Lions at Panthers | Sat, 1 p.m. ET | Panthers -2.5 | OTB |
| Bills at Bears | Sat, 1 p.m. ET | Bears +7 | OTB |
| Saints at Browns | Sat, 1 p.m. ET | OTB | OTB |
| Seahawks at Chiefs | Sat, 1 p.m. ET | Chiefs -10.5 | OTB |
| Giants at Vikings | Sat, 1 p.m. ET | Vikings -5 | OTB |
| Bengals at Patriots | Sat, 1 p.m. ET | Patriots +1 | OTB |
| Texans at Titans | Sat, 1 p.m. ET | Titans -8 | OTB |
| Commanders at 49ers | Sat, 4:05 p.m. ET | 49ers -6 | OTB |
| Eagles at Cowboys | Sat, 4:25 p.m. ET | Cowboys -3.5 | OTB |
| Raiders at Steelers | Sat, 8:20 p.m. ET | Steelers +1.5 | OTB |
| Packers at Dolphins | Sun, 1:00 p.m. ET | Dolphins +1 | OTB |
| Broncos at Rams | Sun, 4:30 p.m. ET | Rams -3 | OTB |
| Buccaneers at Cardinals | Sun, 8:20 p.m. ET | Cardinals +2.5 | OTB |
| Chargers at Colts | Mon, 8:15 p.m. ET | Colts +1 | OTB |
Odds courtesy of DraftKings as of May 13, 2022.
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