NFL Week 16 Odds: Rams Favored Over Broncos on Christmas

Week 16 action starts with TNF, loading up on December 24 and 25, and closing with MNF on Dec. 26. Christmas Day will see Russell Wilson and Aaron Donald meet again, with Week 16 NFL odds installing the Rams as slight favorites.

Last Updated: May 13, 2022 11:52 AM ET Read Time: 8 min
Aaron Donald Los Angeles Rams NFL
Photo By - USA TODAY Sports

Want to celebrate your holidays with the NFL? Well, you don't have much say in the matter, as the league's Week 16 schedule for the 2022 season features the full slate on Saturday, December 24, and three games on Christmas Day.

Helping you get in the spirit on Dec. 25 is a trio of great games and legendary quarterbacks, with Packers and Dolphins kicking things off, followed by the Broncos and Rams in L.A., and coming to a close with the Bucs visiting Arizona to face the Cardinals. 

Here is the list of all the latest NFL Week 16 odds, times, and spreads.

These are the NFL odds for Week 16, headlined by a full three-game slate on Christmas Day, with Tom Brady and the Bucs visiting Kyler Murray and the Cardinals.

Matchup Time Spread Over/Under
Jaguars at Jets Thurs, 8:20 p.m. ET Jets -2.5 OTB
Falcons at Ravens Sat, 1 p.m. ET Ravens -7.5 OTB
Lions at Panthers Sat, 1 p.m. ET Panthers -2.5 OTB
Bills at Bears Sat, 1 p.m. ET Bears +7 OTB
Saints at Browns Sat, 1 p.m. ET OTB OTB
Seahawks at Chiefs Sat, 1 p.m. ET Chiefs -10.5 OTB
Giants at Vikings Sat, 1 p.m. ET Vikings -5 OTB
Bengals at Patriots Sat, 1 p.m. ET Patriots +1 OTB
Texans at Titans Sat, 1 p.m. ET Titans -8 OTB
Commanders at 49ers Sat, 4:05 p.m. ET 49ers -6 OTB
Eagles at Cowboys Sat, 4:25 p.m. ET Cowboys -3.5 OTB
Raiders at Steelers Sat, 8:20 p.m. ET Steelers +1.5 OTB
Packers at Dolphins Sun, 1:00 p.m. ET Dolphins +1 OTB
Broncos at Rams Sun, 4:30 p.m. ET Rams -3 OTB
Buccaneers at Cardinals Sun, 8:20 p.m. ET Cardinals +2.5 OTB
Chargers at Colts Mon, 8:15 p.m. ET Colts +1 OTB

Odds courtesy of DraftKings as of May 13, 2022.

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