NFL Week 4 Odds: Brady and Mahomes Square Off

With the NFL schedule dropping on Thursday night, we can see we'll be treated to some fantastic football to bet on in Week 4. Check out the odds for Kansas City vs. Tampa Bay on SNF and more.

Last Updated: May 13, 2022 11:11 AM ET Read Time: 4 min
Tom Brady Tampa Bay Buccaneers NFL
Photo By - USA TODAY Sports

With the summer months heating up, we're oh so close to the NFL overtaking our weekends, and we now have a full schedule to analyze.

Week 4 odds bring a ton of betting potential, with exciting matchups such as the Buffalo Bills vs. the Baltimore Ravens and the Kansas City Chiefs vs. the Tampa Bay Buccaneers.

Here is the full slate of games for Week 4 and all of the odds.

These are the opening NFL odds for Week 4, headlined by Brady and the Bucs opening as 2.5-point home favorites over Kansas City on Sunday Night FOotball

Matchup Time Spread Over/Under
Dolphins at Bengals Thurs, 8:15 p.m. ET Bengals -4.5 OTB
Vikings at Saints Sun, 10:30 a.m. ET Saints +1 46.5
Browns at Falcons Sun, 1 p.m. ET OTB OTB
Bills at Ravens Sun, 1 p.m. ET Ravens +1 OTB
Commanders at Cowboys Sun, 1 p.m. ET Cowboys -5 OTB
Seahawks at Lions Sun, 1 p.m. ET Lions -1 OTB
Chargers at Texans Sun, 1 p.m. ET Texans +7.5 OTB
Titans at Colts Sun, 1 p.m. ET Colts -3 OTB
Bears at Giants Sun, 1 p.m. ET Giants -2.5 OTB
Jaguars at Eagles Sun, 1 p.m. ET Eagles -6 OTB
Jets at Steelers Sun, 1 p.m. ET Steelers -3.5 OTB
Cardinals at Panthers Sun, 4:05 p.m. ET Panthers +2.5 OTB
Patriots at Packers Sun, 4:25 p.m. ET Packers -5 OTB
Broncos at Raiders Sun, 4:25 p.m. ET PK OTB
Chiefs at Buccaneers Sun, 8:20 p.m. ET Buccaneers -2.5 OTB
Rams at 49ers Mon, 8:15 p.m. ET 49ers +1 OTB

Odds courtesy of DraftKings as of May 13, 2022

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