Three games in NFL Week 11 could be considered the slate's "marquee matchup."
First, the Seattle Seahawks visit the Los Angeles Rams, with the home team favored by a slight 2.5 points. Both teams cleared 40 points in Week 10 wins, claiming victory by 16+ points apiece.
Next, the Kansas City Chiefs and Denver Broncos reignite a rivalry at Mile High. Does KC warrant being 3.5-point road chalk?
Finally, the Sunday Night Football game between the Detroit Lions and Philadelphia Eagles could very well be a preview of the NFC Championship Game.
Here are the opening NFL Week 11 odds and early market moves.
NFL odds Week 11
| Matchup | Spread | Moneyline | Over/Under |
|---|---|---|---|
vs |
Patriots -11.5 | Jets +560 Patriots -800 |
43.5 |
vs |
Dolphins -2.5 | Commanders +128 Dolphins -152 |
47.5 |
vs |
Jaguars +2.5 | Chargers -146 Jaguars +126 |
43.5 |
vs |
Bills -5.5 | Buccaneers +215 Bills -260 |
49.5 |
vs |
Vikings -3 | Bears +136 Vikings -162 |
47.5 |
vs |
Giants +7.5 | Packers -450 Giants +350 |
44.5 |
vs |
Titans +7.5 | Texans -400 Titans +315 |
39.5 |
vs |
Falcons -3.5 | Panthers +164 Falcons -196 |
42.5 |
vs |
Steelers -5.5 | Bengals +190 Steelers -230 |
49.5 |
vs |
Cardinals +3 | 49ers -156 Cardinals +132 |
48.5 |
vs |
Rams -2.5 | Seahawks +124 Rams -146 |
48.5 |
vs |
Broncos +3.5 | Chiefs -188 Broncos +158 |
44.5 |
vs |
Browns +8.5 | Ravens -450 Browns +350 |
40.5 |
vs |
Eagles -1.5 | Lions +106 Eagles -124 |
48.5 |
vs |
Raiders +3.5 | Cowboys -196 Raiders +164 |
50.5 |
Lines as of 11-11
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Jets vs Patriots odds (Thursday, 8:15 p.m. ET, Prime Video)
Opening line
- Patriots -10.5
- Over/Under 44.5
- View full Jets vs. Patriots odds and matchup
- Read our Jets vs. Patriots picks and predictions (coming soon)
The Patriots are heavy favorites at home on Thursday Night Football. New England opened -10.5, and some sportsbooks have already upped this spread as high as Pats -13 on Monday morning. New York could be without top WR Garrett Wilson, who left Sunday’s win over Cleveland with a knee injury. The total opened at 44.5 points.
Also see: full Thursday Night Football odds
Commanders vs Dolphins odds (Sunday, 9:30 a.m. ET, NFL Network)
Opening line
- Dolphins -1.5
- Over/Under 47.5
- View full Commanders vs. Dolphins odds and matchup
- Read our Commanders vs. Dolphins picks and predictions (coming soon)
The NFL heads to Spain for this Sunday morning matchup. Look-ahead lines had Miami as a 1.5-point neutral-site underdog, but with the win over Buffalo in Week 10 and QB Jayden Daniels out for Washington, bookies opened the Dolphins as 1.5-point favorites in Madrid. Some books are dealing Fins -2 on Monday morning. This total opened at 47.5 O/U.
Chargers vs Jaguars odds (Sunday, 1:00 p.m. ET, CBS)
Opening line
- Jaguars +1.5
- Over/Under 44.5
- View full Chargers vs. Jaguars odds and matchup
- Read our Chargers vs. Jaguars picks and predictions (coming soon)
A key AFC clash opened with the Jaguars as 1.5-point home underdogs versus the Chargers and jumped to +2.5 with immediate play on the visitor following L.A.’s win over Pittsburgh on SNF. The total hit the board at 44.5 points.
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Buccaneers vs Bills odds (Sunday, 1:00 p.m. ET, CBS)
Opening line
- Bills -5.5
- Over/Under 50.5
- View full Buccaneers vs. Bills odds and matchup
- Read our Buccaneers vs. Bills picks and predictions (coming soon)
Buffalo comes home after an embarrassing effort in Miami on Sunday. The Bills were -6.5 look-ahead favorites, but the official Week 11 spread opened Buffalo -5.5 on Sunday night. Tampa Bay has several offensive players up in the air for Sunday, which will impact the side and total for this non-conference clash. The total hit the board at 50.5 points and has since slimmed to 49.5 O/U.
Bears vs Vikings odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Vikings -2.5
- Over/Under 45.5
- View full Bears vs. Vikings odds and matchup
- Read our Bears vs. Vikings picks and predictions (coming soon)
The Vikings opened as 2.5-point home favorites for this NFC North matchup, and the vig on the favorite is climbing while other shops have already jumped to the field-goal spread. The Over/Under opened at 45.5 points and took early Over play, pushing the number to 46.5 O/U.
Packers vs Giants odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Giants +7.5
- Over/Under 44.5
- View full Packers vs. Giants odds and matchup
- Read our Packers vs. Giants picks and predictions (coming soon)
The Packers are stumbling into Week 11 on a short week after an ugly home loss to the Eagles on Monday. The Giants could be the solution to those losing ways, however. New York just fired its head coach and QB Jaxson Dart is in concussion protocol. Green Bay opened as a 7.5-point road favorite with the total at 44.5 O/U.
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Texans vs Titans odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Titans +7.5
- Over/Under 38.5
- View full Texans vs. Titans odds and matchup
- Read our Texans vs. Titans picks and predictions (coming soon)
All eyes are on Houston QB C.J. Stroud after he missed Week 10 with a concussion. The Texans still prevailed with backup Davis Mills under center, rallying for a win against Jacksonville. This spread opened Houston -7.5 with the total at 38.5 points.
Panthers vs Falcons odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Falcons -4.5
- Over/Under 42.5
- View full Panthers vs. Falcons odds and matchup
- Read our Panthers vs. Falcons picks and predictions (coming soon)
The Falcons travel back home from a loss in Germany and host the rival Panthers in Week 11. Atlanta hit the board as a 4.5-point home favorite, and that slimmed to -3.5 with initial action on Carolina. This Over/Under opened at 42.5 points.
Bengals vs Steelers odds (Sunday, 1:00 p.m. ET, CBS)
Opening line
- Steelers -5.5
- Over/Under 50.5
- View full Bengals vs. Steelers odds and matchup
- Read our Bengals vs. Steelers picks and predictions (coming soon)
The Steelers struggled on Sunday night, leaving Los Angeles with a bad loss in Week 10. That has Pittsburgh opening as a 5.5-point home favorite versus Cincinnati. Despite that rough outing in prime time, action on the Steelers has this spread up to as high as -6 on Monday morning. The total opened at 50.5 points.
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49ers vs Cardinals odds (Sunday, 4:05 p.m. ET, FOX)
Opening line
- Cardinals +1.5
- Over/Under 47.5
- View full 49ers vs. Cardinals odds and matchup
- Read our 49ers vs. Cardinals picks and predictions (coming soon)
Arizona opened as a 1.5-point home underdog to San Francisco, and money flooded in on the 49ers, moving this spread to Cardinals +3. Arizona suffered a slew of injuries in Sunday’s loss to Seattle, including WR Zay Jones and RB Bam Knight. This total opened at 47.5 points and moved to 48.5 O/U.
Seahawks vs Rams odds (Sunday, 4:05 p.m. ET, FOX)
Opening line
- Rams -2.5
- Over/Under 48.5
- View full Seahawks vs. Rams odds and matchup
- Read our Seahawks vs. Rams picks and predictions (coming soon)
This is a huge game in the NFC pecking order with the Rams hitting the board as 2.5-point home chalk in Week 11. The total opened at 48.5 points. Los Angeles got a scare from veteran WR Davante Adams, who left Week 10 with a back injury. However, he is not expected to miss this matchup with the Seahawks.
Chiefs vs Broncos odds (Sunday, 4:25 p.m. ET, CBS)
Opening line
- Broncos +3.5
- Over/Under 44.5
- View full Chiefs vs. Broncos odds and matchup
- Read our Chiefs vs. Broncos picks and predictions (coming soon)
The Broncos won ugly last Thursday and opened as 3.5-point home underdogs to the Chiefs, with Kansas City coming off a bye. The Over/Under opened at 44.5 points for this crucial AFC West war.
Ravens vs Browns odds (Sunday, 4:25 p.m. ET, CBS)
Opening line
- Browns +8.5
- Over/Under 41.5
- View full Ravens vs. Browns odds and matchup
- Read our Ravens vs. Browns picks and predictions (coming soon)
Baltimore is picking up steam and opened as an 8.5-point road favorite in Cleveland. The total for this AFC North rivalry hit the board at 41.5 points.
Lions vs Eagles odds (Sunday, 8:20 p.m. ET, NBC)
Opening line
- Eagles -1.5
- Over/Under 47.5
- View full Lions vs. Eagles odds and matchup
- Read our Lions vs. Eagles picks and predictions (coming soon)
Sunday Night Football is shaping up to be a massive NFC matchup, with Philadelphia opening as a 1.5-point home favorite hosting Detroit. The Eagles are on a short week after Monday’s win at Green Bay. The total hit the board at 48.5 points.
Also see: full Sunday Night Football odds
Cowboys vs Raiders odds (Monday, 8:15 p.m. ET, ABC/ESPN)
Opening line
- Raiders +3
- Over/Under 49.5
- View full Cowboys vs. Raiders odds and matchup
- Read our Cowboys vs. Raiders picks and predictions (coming soon)
Week 11 comes to a close with a non-conference contest on MNF. Dallas opened as a field-goal favorite, and the vig on the Cowboys is climbing, with some shops moving to Cowboys -3.5. This total opened at 49.5 points and jumped to 50.5 O/U quickly on Sunday night.
Also see: full Monday Night Football odds
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Odds are correct at the time of publishing and are subject to change.
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