NFL Week 11 Odds: 49ers and Cardinals Clash in Mexico

The NFL will play its first game in Mexico since 2019 as the San Francisco 49ers play the Arizona Cardinals on Monday Night Football. Other matchups include the defending AFC champs in Steeltown on Sunday night. Check our latest betting odds for Week 11.

Last Updated: May 13, 2022 11:37 AM ET Read Time: 8 min
Nick Bosa San Francisco 49ers NFL
Photo By - USA TODAY Sports

Week 11 in the 2022 NFL season is headlined by a much-anticipated game in Mexico between the 49ers and Cardinals, as well as some classic Buffalo weather rolling in for Browns at Bills, and an AFC North showdown between the Bengals and Steelers on Sunday Night Football.

Here is the list of all the NFL Week 11 odds coming in at the sportsbook.

These are the current NFL odds for Week 11, with Arizona set as slim favorites for their matchup against San Francisco in Mexico on Sunday Night Football.

Matchup Time Spread Over/Under
Titans at Packers Thurs, 8:20 p.m. ET Packers -4.5 OTB
Bears at Falcons Sun, 1 p.m. ET PK OTB
Panthers at Ravens Sun, 1 p.m. ET Ravens -7 OTB
Browns at Bills Sun, 1 p.m. ET OTB OTB
Commanders at Texans Sun, 1 p.m. ET Texans +3 OTB
Eagles at Colts Sun, 1 p.m. ET Colts -3 OTB
Jets at Patriots Sun, 1 p.m. ET Patriots -6 OTB
Rams at Saints Sun, 1 p.m. ET Saints +3 OTB
Lions at Giants Sun, 1 p.m. ET Giants -1.5 OTB
Raiders at Broncos Sun, 4:05 p.m. ET Broncos -3 OTB
Chiefs at Chargers Sun, 4:25 p.m. ET Chargers -1.5 OTB
Cowboys at Vikings Sun, 4:25 p.m. ET PK OTB
Bengals at Steelers Sun, 8:20 p.m. ET Steelers +2.5 OTB
49ers at Cardinals Mon, 8:15 p.m. ET Cardinals +2.5 48

Teams on bye this week: Jaguars, Buccaneers, Seahawks, Dolphins
Odds courtesy of 
DraftKings as of May 13, 2022

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