Opening NFL Week 11 Odds and Betting Lines: Lions vs. Eagles in SNF Showdown

The Lions and Eagles are featured under the prime-time lights on Sunday Night Football in Week 11. Detroit is a slight 1.5-point underdog at the Linc in what could be a preview of the NFC Championship Game.

Jason Logan: Senior Betting Analyst at Covers
Jason Logan • Senior Betting Analyst
Nov 11, 2025 • 07:19 ET • 4 min read
Opening NFL Week 11 odds
Photo By - Imagn Images. Lions RB Jahmyr Gibbs (0) flexes after a big play.

Three games in NFL Week 11 could be considered the slate's "marquee matchup."

First, the Seattle Seahawks visit the Los Angeles Rams, with the home team favored by a slight 2.5 points. Both teams cleared 40 points in Week 10 wins, claiming victory by 16+ points apiece.

Next, the Kansas City Chiefs and Denver Broncos reignite a rivalry at Mile High. Does KC warrant being 3.5-point road chalk?

Finally, the Sunday Night Football game between the Detroit Lions and Philadelphia Eagles could very well be a preview of the NFC Championship Game.

Here are the opening NFL Week 11 odds and early market moves.

NFL odds Week 11

Matchup Spread Moneyline Over/Under
Jets Jets
vs
Patriots Patriots
Patriots -11.5 Jets +560
Patriots -800
43.5
CommandersCommanders
vs
Dolphins Dolphins
Dolphins -2.5 Commanders +128
Dolphins -152
47.5
Chargers Chargers
vs
Jaguars Jaguars

Jaguars +2.5 Chargers -146
Jaguars +126
43.5
Buccaneers Buccaneers
vs
Bills Bills
Bills -5.5 Buccaneers +215
Bills -260
49.5
Bears Bears
vs
Vikings Vikings
Vikings -3 Bears +136
Vikings -162
47.5
Packers Packers
vs
Giants Giants
Giants +7.5 Packers -450
Giants +350
44.5
Texans Texans
vs
Titans Titans
Titans +7.5 Texans -400
Titans +315
39.5
Panthers Panthers
vs
Falcons Falcons
Falcons -3.5 Panthers +164
Falcons -196
42.5
Bengals Bengals
vs
Steelers Steelers
Steelers -5.5 Bengals +190
Steelers -230
49.5
49ers 49ers
vs
Cardinals Cardinals
Cardinals +3 49ers -156
Cardinals +132
48.5
Seahawks Seahawks
vs
Rams Rams
Rams -2.5 Seahawks +124
Rams -146
48.5
Chiefs Chiefs
vs
Broncos Broncos
Broncos +3.5 Chiefs -188
Broncos +158
44.5
Ravens Ravens
vs
Browns Browns
Browns +8.5 Ravens -450
Browns +350
40.5
Lions Lions
vs
Eagles Eagles
Eagles -1.5 Lions +106
Eagles -124
48.5
Cowboys Cowboys
vs
Raiders Raiders
Raiders +3.5 Cowboys -196
Raiders +164
50.5

Lines as of 11-11

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Jets vs Patriots odds (Thursday, 8:15 p.m. ET, Prime Video)

Opening line

The Patriots are heavy favorites at home on Thursday Night Football. New England opened -10.5, and some sportsbooks have already upped this spread as high as Pats -13 on Monday morning. New York could be without top WR Garrett Wilson, who left Sunday’s win over Cleveland with a knee injury. The total opened at 44.5 points.

Also see: full Thursday Night Football odds

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Commanders vs Dolphins odds (Sunday, 9:30 a.m. ET, NFL Network)

Opening line

The NFL heads to Spain for this Sunday morning matchup. Look-ahead lines had Miami as a 1.5-point neutral-site underdog, but with the win over Buffalo in Week 10 and QB Jayden Daniels out for Washington, bookies opened the Dolphins as 1.5-point favorites in Madrid. Some books are dealing Fins -2 on Monday morning. This total opened at 47.5 O/U.

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Chargers vs Jaguars odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

A key AFC clash opened with the Jaguars as 1.5-point home underdogs versus the Chargers and jumped to +2.5 with immediate play on the visitor following L.A.’s win over Pittsburgh on SNF. The total hit the board at 44.5 points.

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Buccaneers vs Bills odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

Buffalo comes home after an embarrassing effort in Miami on Sunday. The Bills were -6.5 look-ahead favorites, but the official Week 11 spread opened Buffalo -5.5 on Sunday night. Tampa Bay has several offensive players up in the air for Sunday, which will impact the side and total for this non-conference clash. The total hit the board at 50.5 points and has since slimmed to 49.5 O/U.

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Bears vs Vikings odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

The Vikings opened as 2.5-point home favorites for this NFC North matchup, and the vig on the favorite is climbing while other shops have already jumped to the field-goal spread. The Over/Under opened at 45.5 points and took early Over play, pushing the number to 46.5 O/U. 

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Packers vs Giants odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

The Packers are stumbling into Week 11 on a short week after an ugly home loss to the Eagles on Monday. The Giants could be the solution to those losing ways, however. New York just fired its head coach and QB Jaxson Dart is in concussion protocol. Green Bay opened as a 7.5-point road favorite with the total at 44.5 O/U.

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Texans vs Titans odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

All eyes are on Houston QB C.J. Stroud after he missed Week 10 with a concussion. The Texans still prevailed with backup Davis Mills under center, rallying for a win against Jacksonville. This spread opened Houston -7.5 with the total at 38.5 points.

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Panthers vs Falcons odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

The Falcons travel back home from a loss in Germany and host the rival Panthers in Week 11. Atlanta hit the board as a 4.5-point home favorite, and that slimmed to -3.5 with initial action on Carolina. This Over/Under opened at 42.5 points.

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Bengals vs Steelers odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

The Steelers struggled on Sunday night, leaving Los Angeles with a bad loss in Week 10. That has Pittsburgh opening as a 5.5-point home favorite versus Cincinnati. Despite that rough outing in prime time, action on the Steelers has this spread up to as high as -6 on Monday morning. The total opened at 50.5 points.

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49ers vs Cardinals odds (Sunday, 4:05 p.m. ET, FOX)

Opening line

Arizona opened as a 1.5-point home underdog to San Francisco, and money flooded in on the 49ers, moving this spread to Cardinals +3. Arizona suffered a slew of injuries in Sunday’s loss to Seattle, including WR Zay Jones and RB Bam Knight. This total opened at 47.5 points and moved to 48.5 O/U.

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Seahawks vs Rams odds (Sunday, 4:05 p.m. ET, FOX)

Opening line

This is a huge game in the NFC pecking order with the Rams hitting the board as 2.5-point home chalk in Week 11. The total opened at 48.5 points. Los Angeles got a scare from veteran WR Davante Adams, who left Week 10 with a back injury. However, he is not expected to miss this matchup with the Seahawks.

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Chiefs vs Broncos odds (Sunday, 4:25 p.m. ET, CBS)

Opening line

The Broncos won ugly last Thursday and opened as 3.5-point home underdogs to the Chiefs, with Kansas City coming off a bye. The Over/Under opened at 44.5 points for this crucial AFC West war. 

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Ravens vs Browns odds (Sunday, 4:25 p.m. ET, CBS)

Opening line

Baltimore is picking up steam and opened as an 8.5-point road favorite in Cleveland. The total for this AFC North rivalry hit the board at 41.5 points.

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Lions vs Eagles odds (Sunday, 8:20 p.m. ET, NBC)

Opening line

Sunday Night Football is shaping up to be a massive NFC matchup, with Philadelphia opening as a 1.5-point home favorite hosting Detroit. The Eagles are on a short week after Monday’s win at Green Bay. The total hit the board at 48.5 points.

Also see: full Sunday Night Football odds

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Cowboys vs Raiders odds (Monday, 8:15 p.m. ET, ABC/ESPN)

Opening line

Week 11 comes to a close with a non-conference contest on MNF. Dallas opened as a field-goal favorite, and the vig on the Cowboys is climbing, with some shops moving to Cowboys -3.5. This total opened at 49.5 points and jumped to 50.5 O/U quickly on Sunday night.

Also see: full Monday Night Football odds

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Best NFL bets this week

Looking for our favorite spread, total, and NFL prop bets for this week's action? Check out our best free NFL picks from the Covers staff!

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Jason Logan Senior Industry Analyst Covers.com
Senior Betting Analyst

In his 20 years with Covers, lead NFL betting analyst; has seen it all and bet it all. Through the wild west of early Internet gambling to lobbying for legalized sports betting to our brave new wagering world, Jason has been a consistent source of actionable info and entertainment for squares and sharps alike. Since joining the Covers team back in 2005, he honed his handicapping skills to provide audiences with the most thorough insights, blending traditional capping methods with advanced modelling and predictive analysis. Jason has studied the ins and outs of the sports betting business, learning from some of the most successful gamblers in the industry and the biggest sportsbook operators on the planet. He is under center for Covers during NFL season as our top NFL expert, taking the points in his infamous NFL Underdogs column and representing the Covers Community at the Super Bowl. While he lives for football season, Jasons first love is basketball and that shows in his in-depth NBA, NCAA, and WNBA betting breakdowns. On top of being a mainstay in media from coast to coast; WPIX, PHL17, Fox 5 San Diego, WGNO, TSN, SportsNet, ESPN Radio; he had his analysis featured in USA Today, MSNBC, ESPN, the Wall Street Journal, CBS, Bloomberg, the L.A. Times, the New York Times and other major publications. You can also find JLo stuffing all the top picks and predictions he can into 10 minutes as the host of Covers; flagship podcast, The Sharp 600.

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