The NFL Week 11 odds are bookended by two massive games.
The Week 11 slate wraps up with a Super Bowl rematch on Monday Night Football with the Philadelphia Eagles heading to Arrowhead to get revenge against the Kansas City Chiefs.
Here's a complete look at the opening NFL Week 11 odds and the early adjustments.
NFL Week 11 odds, lines, and spreads
These are the live NFL odds for Week 11, highlighting the best odds available from regulated sportsbooks within your area.
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Bengals vs. Ravens odds
Opening line
- Ravens -4
- Over/Under 44
- View full Bengals vs. Ravens line movement
- Read our Bengals vs. Ravens picks and predictions
The Ravens and Bengals both come off losses in Week 10, potentially looking ahead to this short-week showdown on Thursday Night Football. Baltimore opened as a 4-point home favorite and that line has climbed to -4.5 on Sunday night. The total for this AFC North rivalry hit the board as low as 43 and it sitting as high as 44.5 points.
Also see: full Thursday Night Football odds
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Cowboys vs. Panthers odds
Opening line
- Panthers +10
- Over/Under 42
- View full Cowboys vs. Panthers line movement
- Read our Cowboys vs. Panthers picks and predictions
With the Cowboys crushing the Giants in Week 10, oddsmakers are expecting another squash when Dallas comes to Carolina in Week 11. The Panthers get a mini-bye after losing last Thursday and have a lot to figure out on offense before facing this disruptive Dallas defense. The total for this game opened at 42 points and is up to 43.5.
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Steelers vs. Browns odds
Opening line
- Browns -4
- Over/Under 38.5
- View full Steelers vs. Browns line movement
- Read our Steelers vs. Browns picks and predictions
Cleveland somehow stunned the Ravens in Week 10 and now that defense sets its sights on the Steelers at home in Week 11. Quarterback Deshaun Watson left that game in a walking boot but told the media he would be fine to play next Sunday. That has this spread trimming to Browns -3.5 on Sunday night. The total is at 38.5 points.
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Bears vs. Lions odds
Opening line
- Lions -9
- Over/Under 47
- View full Bears vs. Lions line movement
- Read our Bears vs. Lions picks and predictions
Detroit opened as low as 9-point home favorites for this NFC North rivalry and the market is up to -10 at many books on Sunday night. The big question is the status of Chicago QB Justin Fields, who has sat out the past three games yet has practiced with limited work. The total for this game opened at 47 points and is down to 46.5 on Sunday night.
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Chargers vs. Packers odds
Opening line
- Packers +3
- Over/Under 44
- View full Chargers vs. Packers line movement
- Read our Chargers vs. Packers picks and predictions
Both teams are coming off a loss and Los Angeles has to cross the country for a 1 p.m. ET start in Lambeau Field. The Bolts opened as 3-point road chalk with that spread trending toward -3.5 on Sunday night. The Over/Under total opened at 44 points.
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Cardinals vs. Texans odds
Opening line
- Texans -5.5
- Over/Under 49
- View full Cardinals vs. Texans line movement
- Read our Cardinals vs. Texans picks and predictions
The look-ahead lines for this non-conference clash had Houston laying -3.5 and the total was at 47 points. Then the Texans took down the Bengals with an impressive scoring display and Kyler Murray came back to lead Arizona to a victory over Atlanta. Houston is now laying -5.5 at home and the total is pumped up to 49 points on Sunday night.
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Titans vs. Jaguars odds
Opening line
- Jaguars -6.5
- Over/Under 40
- View full Titans vs. Jaguars line movement
- Read our Titans vs. Jaguars picks and predictions
Jacksonville watched its five-game winning streak shattered by San Francisco but has a shot to get back on track against the Titans in Week 11. Tennessee looked terrible in a loss at Tampa Bay and opened as a 6.5-point road underdog for what will be its third straight road game. The total opened at 40 points.
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Raiders vs. Dolphins odds
Opening line
- Dolphins -13
- Over/Under 48.5
- View full Raiders vs. Dolphins line movement
- Read our Raiders vs. Dolphins picks and predictions
The Dolphins are coming off a bye, are 4-0 at home this season, and opened as big 13-point home favorites over the streaking Las Vegas Raiders. The visitors are unbeaten (2-0) under interim head coach Antonio Pierce with back-to-back home wins over New York-based teams. The total for this Sunday afternoon matchup opened at 48.5.
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Giants vs. Commanders odds
Opening line
- Commanders -9.5
- Over/Under 37
- View full Giants vs. Commanders line movement
- Read our Giants vs. Commanders picks and predictions
Washington was a 7.5-point favorite on the look-ahead line but after New York was rolled by Dallas, books opened the Commanders as 9.5-point home chalk and that is sitting as high as -10 at some books on Sunday night. This total is bouncing between 36 and 37 points.
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Buccaneers vs. 49ers odds
Opening line
- 49ers -10
- Over/Under 42
- View full Buccaneers vs. 49ers line movement
- Read our Buccaneers vs. 49ers picks and predictions
The 49ers sent a reminder across the league, snapping their three-game losing skid by ending Jacksonville's winning ways. Books opened San Francisco as a 10-point home fave and many books are now on the other side of the key number, dealing 49ers -10.5. This total opened at 42 points at most books.
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Jets vs. Bills odds
Opening line
- Bills -8
- Over/Under 40.5
- View full Jets vs. Bills line movement
- Read our Jets vs. Bills picks and predictions
The Jets looked awful in their 16-12 loss in Vegas on Sunday Night Football in Week 10. This week the Jets shuffle off to Buffalo to face a Bills team coming off a heartbreaking 24-22 loss to the Denver Broncos on Monday night. Oddsmakers opened the Bills as big 8-point home favorites with a total of 40.5.
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Seahawks vs. Rams odds
Opening line
- Rams +2.5
- Over/Under 44
- View full Seahawks vs. Rams line movement
- Read our Seahawks vs. Rams picks and predictions
The Rams are coming off a bye in Week 10 and hit the board as 2.5-point home underdogs in somewhat of a revenge game for Seattle, which was stunned by L.A. in Week 1. The Seahawks are coming off a wild win over Washington and that has this total ticking up to 44.5 points.
Best NFL bets this week
Looking for our favorite spread, total, and NFL prop bets for this week's action? Check out our best free NFL picks from the Covers staff!
Vikings vs. Broncos odds
Opening line
- Broncos -2.5
- Over/Under 43
- View full Vikings vs. Broncos line movement
- Read our Vikings vs. Broncos picks and predictions
The Broncos hopped into their getaway cars and sped out of Buffalo with a 24-22 victory over the Bills on Monday Night Football. Josh Dobbs and the Minnesota Vikings are up next for the Broncos as the SKOL crew sails into Denver for Sunday Night Football in Week 11. Oddsmakers opened the Broncos as 2.5-point home favorites with a total of 43.
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Eagles vs. Chiefs odds
Opening line
- Chiefs -2.5
- Over/Under 48
- View full Eagles vs. Chiefs line movement
- Read our Eagles vs. Chiefs picks and predictions
Remember how awesome Super Bowl LVII was? We get to do it all over again in Arrowhead, with the Eagles getting 2.5 points as road pups against the Chiefs in Week 11. Both teams are coming off the bye, so health shouldn't be too much of an issue and the extended forecast says early showers should clear before kickoff. The total opened at 48 points and is down to 47.5 at some shops. Let's hope this lives up to the "Game of the Year" billing.
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More weekly NFL odds content
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