The Green Bay Packers are favored by 3.5 points when the Carolina Panthers visit Lambeau Field on Thursday, Oct. 29, at 8:15 p.m. ET.
My Panthers vs. Packers prediction backs the visitors and a remarkable bounce-back trend: 13 straight covers following an outright loss.
Let’s dive into my NFL picks for the Week 8 opener, with the game airing on Prime Video.
TOP Pick
Panthers vs Packers prediction: Panthers +3.5
My favorite active betting trend is on the line: the Carolina Panthers are 13-0 ATS in their last 13 games following an outright loss. I’ll happily back them again to +3.
They just got obliterated 43-13 by Tampa Bay, but remember last season? Carolina followed a 31-point home loss to Buffalo by winning outright at Lambeau Field as a 13.5-point underdog.
Conveniently, the Green Bay Packers are 1-9-1 ATS in their last 11 after an outright loss and 4-11-1 ATS in their last 16 as a favorite.
Green Bay holds a slight edge in net yards per play, but barely escaped lesser competition earlier this season, beating the Bucs and Jets by just three points each.
No one bounces back like the Panthers. Give me the points!

Panthers vs Packers combo
Carolina’s 13-0 ATS run after outright losses gets this combo started.
Remember what happened in the Packers’ last Thursday home appearance as a favorite? They completely no-showed, getting manhandled 35-14 by Atlanta just a few weeks ago.
For the Under, Green Bay’s last four games have averaged just 35.5 combined points, while Carolina’s last six road games didn’t even reach 40.
We don’t need an offensive explosion to cash the touchdown leg, either. Chuba Hubbard has six scores in six games, and one trip to the end zone fits nicely with a competitive game that stays below this total.
Panthers vs Packers combo
- Panthers +3.5
- Under 47.5
- Chuba Hubbard anytime touchdown
Panthers vs Packers touchdown scorer: Chuba Hubbard
Green Bay has already surrendered 10 touchdowns to running backs, giving us another reason to like Carolina’s lead back near the goal line.
I also absolutely love that he’s coming off a light day against Tampa Bay, finishing with just seven carries. The blowout was ugly, but avoiding another heavy workload is a nice bonus heading into Thursday’s quick turnaround.
- Top picks: 3-4, -1.18 units
- Combos: 0-7, -7.00 units
Panthers vs Packers odds
For help understanding probabilities, see our odds calculator.
- Spread: Panthers +3.5 | Packers -3.5
- Over/Under: Over 47.5 (54%) | Under 47.5 (51%)
- Moneyline: Panthers 36% | Packers 64%
For the full slate of NFL matchups, check out our NFL odds board!
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Panthers vs Packers weather
The current kickoff forecast calls for mostly clear skies, approximately 56°F and light winds around 4 mph, with a 15% chance of precipitation.
Check out our NFL weather page for up-to-date info on every matchup.
Panthers vs Packers trend to know
The Panthers have gone Under in six straight road games. Find more NFL betting trends for Panthers vs. Packers.
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How to watch Panthers vs Packers
| Location | Lambeau Field, Green Bay, WI |
| Date | Thursday, Oct. 29, 2026 |
| Kickoff | 8:15 p.m. ET |
| TV | Prime Video |
Panthers vs Packers latest injuries
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Odds are correct at the time of publishing and are subject to change.
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