NFL Week 2 Odds: Packers Big Faves on MNF

Check out the latest NFL odds, lines moves, and betting splits for the Week 2 Monday Night Football game between the Green Bay Packers, who are coming off a season-opening stinker, and the Detroit Lions.

Last Updated: Sep 12, 2021 9:24 PM ET Read Time: 8 min

After an exciting opening week of NFL betting, we're looking ahead to NFL Week 2 with several interesting games to look forward to, including the Chiefs visiting the Ravens on Sunday Night Football.

Week-long betting action has moved the NFL Week 2 odds on some games, with the Ravens growing underdogs for their Sunday night showdown with the Chiefs and a number of Over/Under totals on the rise with one-side money banking on high-scoring results this Sunday.

Here are all of the NFL Week 2 odds and line moves to know.

These are the opening NFL odds for Week 2, headlined by the Chiefs as 3.5-point road favorites over the Ravens after the game opened as a pick'em with the lookahead lines back in the spring.

Matchup Time Spread Over/Under
Giants at Washington Thurs, 8:20 p.m. ET Washington -3.5 41
Patriots at Jets Sun, 1 p.m. ET Jets +6 43
Broncos at Jaguars Sun, 1 p.m. ET Jaguars +6 45.5
Bills at Dolphins Sun, 1 p.m. ET Dolphins +3.5 48
49ers at Eagles Sun, 1 p.m. ET Eagles +3 49
Rams at Colts Sun, 1 p.m. ET Colts +3.5 48
Raiders at Steelers Sun, 1 p.m. ET Steelers -6.5 46.5
Bengals at Bears Sun, 1 p.m. ET Bears -1.5 44.5
Texans at Browns Sun, 1 p.m. ET Browns -13.5 47.5
Saints at Panthers Sun, 1 p.m. ET Panthers +3.5 45
Vikings at Cardinals Sun, 4:05 p.m. ET Cardinals -4 50.5
Falcons at Buccaneers Sun 4:05 p.m. ET Buccaneers -12.5 51.5
Titans at Seahawks Sun, 4:25 p.m. ET Seahawks -6.5 54
Cowboys at Chargers Sun, 4:25 p.m. ET Chargers -3 55
Chiefs at Ravens Sun, 8:20 p.m. ET Ravens +3.5 53.5
Lions at Packers Mon, 8:15 p.m. ET Packers -12 49

Odds courtesy of DraftKings Sportsbook as of 7 a.m. ET September 19, 2021

Best NFL sign-up bonuses

If you're signing up for a new sportsbook for NFL Week 2, here are two of the best welcome bonuses available:

USA: Risk-free bet up to $5,000 plus get a free NFL jersey at Caesars. Claim Now

Canada: 100% matched free bet up to $400 at BetVictor. Claim Now

Opening line

Washington -3, Over/Under 43

Why the line moved

UPDATE 5:50 P.M. THURSDAY, SEPT 16: After sitting anywhere from -4.5 to -3.5 earlier in the week, the spread for this Thursday Night Football matchup sat at Washington -3 roughly eight hours before kickoff. However, just two hours out from kickoff and it has moved back to -3.5 at DraftKings as action has continued to be on the Football Team throughout the week and on game day.

The action has gotten even closer with our Covers Consensus, with now just 53 percent of ATS bets placed on WFT. While the total has remained at 41 at DraftKings throughout Thursday, Covers Consensus is still seeing 61 percent of action coming in on the Under.

Opening line

Jets +3, Over/Under 42.5

Why the line moved

UPDATE 7:20 A.M. SUNDAY, SEPT 19: The Patriots are one of the most popular picks for Week 2, with sportsbook reporting one-sided bet count and money on New England and our unbiased Covers Consensus showing 65 percent of picks on the Pats.

This spread is sitting New England -6 (-110) at most books and plenty of parlay and teaser liability will be tied into this 1 p.m. ET kickoff. 

BACK TO TOP

Opening line

Jaguars +1.5, Over/Under 43.5

Why the line moved

UPDATE 7:30 A.M. SUNDAY, SEPT 19: Denver -6 has been on the board for most of the week, with the line quickly flirting with -6.5 at some books. 

DraftKings sportsbook is reporting nearly 90 percent of handle sitting on the road team while 75 percent of bets are also on the Broncos. This is another game with major parlay and teaser liability linked to it. 

Opening line

Dolphins +3.5, Over/Under 48.5

Why the line moved

UPDATE 7:35 A.M. SUNDAY, SEPT 19: According to our Covers Consensus, 63 percent of picks are banking on a bounce-back game from the Bills in Week 2. This spread has stayed steady since moving to Buffalo -3.5 earlier in the week. 

The total for this AFC East rivalry has jumped between 47.5 and 48 points all week, with sportsbooks showing a slight lean to the Over in terms of bet count and handle on the Over/Under. The temperature for today’s game in Miami is expected to hit a “feels like” temperature of 98 degrees due to 70 percent humidity in Miami Gardens.  

Opening line

Eagles +4, Over/Under 46

Why the line moved

UPDATE 7:45 A.M. SUNDAY, SEPT 19: The 49ers briefly slipped to -2.5 on Saturday at some sportsbooks before money swooped in and grabbed the favorite under the key number of a field goal. Many shops are now sitting Eagles +3 (-115) with a reported 60 percent of bets and handle on San Francisco. 

This total went for a ride as well this week, opening as low as 47.5 points and climbing to 50.5 earlier in the week before sliding back down to 49 points as of Sunday morning. 

Opening line

Colts -1.5, Over/Under 49.5

Why the line moved

UPDATE 7:50 A.M. SUNDAY, SEPT 19: Los Angeles is one of the most popular picks for Week 2, according to our Covers Consensus which shows 71 percent of picks on the Rams. The spread for this non-conference clash has dropped from -4.5 to -3.5 but some online books are dealing Indianapolis +4 as of Sunday morning. 

BACK TO TOP

Opening line

Steelers -5.5, Over/Under 49

Why the line moved

UPDATE 8:00 A.M. SUNDAY, SEPT 19: The spread was as high as Pittsburgh -6.5 on Friday but as we get closer to kickoff, the line has slimmed as much as -5.5 at some sportsbooks. 

The bulk of bookmakers are posting a 6-point spread and DraftKings is reporting 68 percent lean in handle toward the home team with Las Vegas having to travel cross-country on a short week after a thrilling victory on Monday Night Football.

The total for this game opened at 48 points and has dropped to as low as 46 before coming back to 46.5. PointsBet sportsbooks were reporting a 55 percent of tickets on the Over but 69 percent of the handle on the Under.  

Opening line

Bears -3.5, Over/Under 45.5

Why the line moved

UPDATE 8:05 A.M. SUNDAY, SEPT 19: The betting public is passionately fading Chicago in Week 2, trimming this spread from Bears -3 to -1.5 as of Sunday morning. It wouldn’t be a surprise to see this spread close with Chicago as a slim home under by the 1 p.m. ET kickoff.

However, while bet counts are leaning heavily toward the visiting Bengals, the handle – money wagered – on the game is not as decisive. Heading into the week, books were reporting a nearly split handle or even more money resting on the Bears. Our Covers Consensus, a more educated bet split than public-inflated counts at the operators shows 59 percent of picks on Cincinnati.

Opening line

Browns -13.5, Over/Under 46

Why the line moved

UPDATE 8:10 A.M. SUNDAY, SEPT 19: Cleveland opened as low as -11.5 for this matchup with Houston and quickly moved to -12.5. While that spread stayed steady most of the week, action on the Browns is moving this line toward two touchdowns at -13.5. 

According to our Covers Consensus, since moving to -13 and -13.5, picks on the Texans are outnumbering those on the Browns, so a move to -14 at sportsbooks may not happen. As of Sunday, 54 percent of picks are taking the points with Houston. 

Opening line

Panthers +2.5, Over/Under 47.5

Why the line moved

UPDATE 8:15 A.M. SUNDAY, SEPT 19: If you’re searching for reverse line movement to tip off where the sharp money is landing, look no further than Saints at Panthers. Carolina was as big as -4.5 earlier in the week, but this spread has slimmed to a field goal despite close to 80 percent of bet count on New Orleans. 

However, the handle split is not as one-sided – still 64 percent toward NOLA – and the line has trimmed to the key number of three at some books. There are still Panthers +3.5 spreads out there, so if you like the underdog shop around for the half-point hook. 

BACK TO TOP

Opening line

Cardinals -3.5, Over/Under 49.5

Why the line moved

UPDATE 8:20 A.M. SUNDAY, SEPT 19: This spread has come down from the dead number of Arizona -4.5 to -3.5 but back to -4 at some shops, with our Covers Consensus showing 71 percent of picks on the home side.

DraftKings sportsbooks are reporting similar betting patterns, with 85 percent of bets and 82 percent of the handle on the home team. The Vikings have some impactful injuries on the defensive side of the ball and which has the Cardinals as low as -3.5 (-115) which is quickly going to -4. 

Opening line

Buccaneers -9.5, Over/Under 52

Why the line moved

UPDATE 8:45 A.M. SUNDAY, SEPT 19: Tampa Bay has climbed as high as -13 for this NFC South showdown after sitting at -12.5 for most of the week. The Bucs were drawing close to 70 percent of the bet count at PointsBet sportsbooks but the bulk of the handle was taking the points with the Falcons. According to our Covers Consensus, 61 percent of picks aren’t shying away from the larger spread and laying the lumber with Tampa Bay. 

This total has also adjusted since opening, hitting the board as high as 53 points and getting bet down to 51.5 as of Sunday morning. Books are reporting bet counts above 60 percent in favor of the Over, indicating sharper action could be leaning Under in this divisional contest. 

Opening line

Seahawks -3.5, Over/Under 49

Why the line moved

UPDATE 8:35 A.M. SUNDAY, SEPT 19: This spread moved down from Seattle -6 to -5.5 earlier in the week but has jumped back up as high as -6.5 as of Sunday morning. Covers Consensus shows 55 percent of picks on the host Seahawks while DraftKings is reporting a 60 percent lean in handle toward the home side. This total has undergone significant movement as well, rising from 52.5 to 54.5 points as of Sunday morning. 

Opening line

Chargers -1.5, Over/Under 52

Why the line moved

UPDATE 8:50 A.M. SUNDAY, SEPT 19: This spread jumped from Chargers -2.5 to -3.5 earlier in the week, however, that line has slimmed to -3 as of Sunday morning. According to our Covers Consensus, 61 percent of picks are on Dallas – echoing the betting splits at sportsbook operators, who are reporting 74 percent of the handle and 73 percent of ticket count on the Cowboys – who should be right at home in SoFi Stadium with a strong California fanbase.

The total for this non-conference kickoff opened as low as 50.5 and jumped to 52 points a few hours after opening. It continued to move up to 55.5 and sits at 55 points at most shops. Almost 80 percent of tickets on the total are picking the Over. 

BACK TO TOP

Opening line

PK, Over/Under 51.5

Why the line moved

UPDATE 9:00 A.M. SUNDAY, SEPT 19: The spread for Sunday night’s epic AFC showdown between the Chiefs and Ravens is sitting at Baltimore +3.5 after quick moved to +4 on Saturday, which were bought up with action on the underdog. 

This is one of the most one-sided bet counts on the board in Week 2, with operators drawing 87 percent of tickets and 94 percent of handle on the visiting Chiefs. A ton of parlay liability will also be rolling into Sunday’s finale, with any surviving accumulators likely riding on Kansas City to cover. 

This total has slimmed from the opened of 55.5 points to as low as 53.5 before jumping back to 54. Covers Consensus is showing 69 percent of total picks on the Over. 

Opening line

Packers -7.5, Over/Under 47.5

Why the line moved

UPDATE 9:40 P.M. SUNDAY, SEPT 19: Green Bay climbed as high as -12.5 for the Monday night matchup with Detroit but some shops were still hanging -11.5 as of Sunday morning, with DraftKings setting it at Packers -12 on Sunday night. Our Covers Consensus shows 54 percent of picks are taking the points with Detroit while operators are reporting between 61 and 77 percent of handle riding on the Cheeseheads at home.

More weekly NFL odds content

Where can I bet on the NFL?

You can bet on NFL odds at every online and casino sportsbook, including NFL moneylines, spreads, Over/Under totals, and a ton of NFL prop odds. Head over to our best-suggested sportsbooks for the top spots to bet on NFL odds in your area.

Popular Content

Covers Contests Icon

Free Contests

Test your handicapping skills for a chance to win over $200,000 in prizes
Play free contests
Covers 25 Years Logo Established in 1995,
Covers is the world
leader in sports
betting information.
Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo