After one of the craziest early slates in recent memory, we're left with two games tonight.
Tampa Bay and Houston kick things off early, while the Chargers head to Vegas as field goal faves to close out the week.
Let's dig into the opening spreads and totals, along with early line movement, in the updated NFL odds for Week 2.
NFL odds Week 2
| Matchup | Spread | Moneyline | Over/Under |
|---|---|---|---|
 Brownsvs  Ravens |
Ravens -11.5 | Browns +590 Ravens -850 |
45.5 |
 Billsvs  Jets |
Jets +6.5 | Bills -295 Jets +240 |
47.5 |
 Patriotsvs  Dolphins |
Dolphins -2.5 | Patriots +110 Dolphins -130 |
43.5 |
 49ersvs  Saints |
Saints +3 | 49ers -154 Saints +130 |
40.5 |
 Seahawksvs  Steelers |
Steelers -3 | Seahawks +134 Steelers -158 |
40.5 |
 Ramsvs  Titans |
Titans +5.5 | Rams -255 Titans +210 |
41.5 |
 Bearsvs  Lions |
Lions -6.5 | Bears +235 Lions -290 |
46.5 |
 Jaguarsvs  Bengals |
Bengals -3.5 | Jaguars +146 Bengals -174 |
49.5 |
 Giantsvs  Cowboys |
Cowboys -4.5 | Giants +198 Cowboys -240 |
44.5 |
 Panthersvs  Cardinals |
Cardinals -6.5 | Panthers +260 Cardinals -320 |
44.5 |
 Broncosvs  Colts |
Colts +2.5 | Broncos -120 Colts +102 |
43.5 |
 Eaglesvs  Chiefs |
Chiefs +1.5 | Eagles -118 Chiefs +100 |
46.5 |
 Falconsvs  Vikings |
Vikings -3.5 | Falcons +152 Vikings -180 |
44.5 |
 Buccaneersvs  Texans |
Texans -2.5 | Buccaneers +128 Texans -152 |
42.5 |
 Chargersvs  Raiders |
Raiders +3 | Chargers -180 Raiders +152 |
46.5 |
Lines as of 9-15.
Browns vs Ravens odds (Sunday, 1:00 p.m. ET, CBS)
Opening line
- Ravens -11.5
- Over/Under 45.5
- View full Browns vs. Ravens odds and matchup
- Read our Browns vs. Ravens picks and predictions (coming soon)
The Ravens need to overcome a brutal collapse at Buffalo in Week 1 before facing the Browns’ defense. Cleveland gave Cincinnati fits in an opening loss, but it was a couple miscues on offense that made the difference. This line opened -11.5 after the look-ahead was -12.5, and the total hit the board at 45.5 O/U.
Bills vs Jets odds (Sunday, 1:00 p.m. ET, CBS)
Opening line
- Jets +6.5
- Over/Under 45.5
- View full Bills vs. Jets odds and matchup
- Read our Bills vs. Jets picks and predictions (coming soon)
Following the Jets battle with the Steelers in Week 1, this line re-opened at Bills -6.5 — a point shorter than the -7.5 look-ahead. But after Buffalo’s crazy comeback against Baltimore on Sunday night, the spread went to a touchdown. This total also made a move from the look-ahead number of 44.5 to 45.5, with New York’s new offense showing life against the Pittsburgh defense.
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Patriots vs Dolphins odds (Sunday, 1:00 p.m. ET, CBS)
Opening line
- Dolphins -2.5
- Over/Under 43.5
- View full Patriots vs. Dolphins odds and matchup
- Read our Patriots vs. Dolphins picks and predictions (coming soon)
No team looked as bad as Miami in Week 1, which is why the Dolphins went from -2.5 to -1.5 for this home opener against New England. A turnover-marred mess has also impacted the Over/Under, opening this total at 43.5 after a look-ahead number of 44.5 O/U.
49ers vs Saints odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Saints +7
- Over/Under 44.5
- View full 49ers vs. Saints odds and matchup
- Read our 49ers vs. Saints picks and predictions (coming soon)
This one sees a significant move from the look-ahead line and early action. San Francisco was a 7.5-point favorite before Week 1. After a struggle with Seattle and the Saints showing fight against Arizona, this spread officially opened Niners -7 and dropped below the key number to -6.5. The total also slid from 44.5 to 43.5 points. Keep an eye on the status of San Francisco WR Juan Jennings (shoulder) and TE George Kittle (hamstring).
Seahawks vs Steelers odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Steelers -2.5
- Over/Under 40.5
- View full Seahawks vs. Steelers odds and matchup
- Read our Seahawks vs. Steelers picks and predictions (coming soon)
The Steelers opened as 2.5-point home favorites and made a quick run to -3 before being bet back down to the opener. Pittsburgh has injuries in the secondary to monitor this week with Joey Porter Jr. and DeShon Elliott leaving Week 1 with injuries. This total opened at 40.5 points.
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Rams vs Titans odds (Sunday, 1:00 p.m. ET, CBS)
Opening line
- Titans +4.5
- Over/Under 42.5
- View full Rams vs. Titans odds and matchup
- Read our Rams vs. Titans picks and predictions (coming soon)
Los Angeles opened as 4.5-point road favorites in Tennessee, and that jumped to -5.5 with early money on the Rams. This total opened at 42.5 points, two points shorter than the look-ahead lines.
Bears vs Lions odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Lions -4.5
- Over/Under 47.5
- View full Bears vs. Lions odds and matchup
- Read our Bears vs. Lions picks and predictions (coming soon)
The Bears couldn’t keep it together on Monday Night Football and now head to Detroit to face the Lions coming off a loss in Week 1. The look-ahead line was Detroit -5.5 and re-opened at -4.5. The total was at 48.5 points before MNF and is now down to 47.5 O/U.
Jaguars vs Bengals odds (Sunday, 1:00 p.m. ET, CBS)
Opening line
- Bengals -4.5
- Over/Under 49.5
- View full Jaguars vs. Bengals odds and matchup
- Read our Jaguars vs. Bengals picks and predictions (coming soon)
The Bengals got an ugly win in Week 1 and opened as 4.5-point favorites hosting Jacksonville — a point shorter than the look-ahead spread. That slimmed to -3.5 with action on the Jaguars. This total opened at 49.5 and jumped to 50.5 overnight.
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Giants vs Cowboys odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Cowboys -3
- Over/Under 44.5
- View full Giants vs. Cowboys odds and matchup
- Read our Giants vs. Cowboys picks and predictions (coming soon)
The Cowboys enjoy a mini-bye to prep for Week 2 after a loss at Philadelphia in Week 1. Dallas opened as a 4.5-point favorite and we’re seeing market movement to -5 at many books on Monday morning. This total hit the board at 44.5 points.
Panthers vs Cardinals odds (Sunday, 4:05 p.m. ET, CBS)
Opening line
- Cardinals -6.5
- Over/Under 45.5
- View full Panthers vs. Cardinals odds and matchup
- Read our Panthers vs. Cardinals picks and predictions (coming soon)
After a Panthers loss and a Cardinals win, this spread opened at Arizona -6.5 — a point higher than the look-ahead line. The total opened at 45.5 points.
Broncos vs Colts odds (Sunday, 4:05 p.m. ET, CBS)
Opening line
- Colts +3
- Over/Under 44.5
- View full Broncos vs. Colts odds and matchup
- Read our Broncos vs. Colts picks and predictions (coming soon)
The Broncos avoided a Week 1 upset to the Titans and now travel to Indianapolis. The Colts thumped the Dolphins in the home opener and hit the board as 2.5-point underdogs in Week 2. This total is down two points to 42.5 after opening at 44.5 O/U.
Eagles vs Chiefs odds (Sunday, 4:25 p.m. ET, FOX)
Opening line
- Chiefs +1.5
- Over/Under 45.5
- View full Eagles vs. Chiefs odds and matchup
- Read our Eagles vs. Chiefs picks and predictions (coming soon)
A Super Bowl LIX rematch is the must-see matchup of Week 2. The Chiefs opened as 1.5-point home underdogs to the Eagles following their Week 1 loss in Brazil. However, this line has slimmed to Eagles -1 at most books and some have jumped the fence to Chiefs -1.5. Kansas City was a 1.5-point home favorite on the look-ahead line but is missing some key weapons in this offense, including WR Xavier Worthy. This Over/Under number opened at 45.5 points.
Falcons vs Vikings odds (Sunday, 8:20 p.m. ET, NBC)
Opening line
- Vikings -4.5
- Over/Under 45.5
- View full Falcons vs. Vikings odds and matchup
- Read our Falcons vs. Vikings picks and predictions (coming soon)
The Vikings are fresh off a comeback win on Monday night and officially opened as a 4.5-point home favorite while many sportsbook are already at -5. The look-ahead total was at 44.5 and jumped to 45.5 O/U after Minnesota’s Week 1 win.
Also see: full Sunday Night Football odds
Buccaneers vs Texans odds (Monday, 7:00 p.m. ET, ABC/ESPN)
Opening line
- Texans -2.5
- Over/Under 44.5
- View full Buccaneers vs. Texans odds and matchup
- Read our Buccaneers vs. Texans picks and predictions
Houston opened as high as -2.5 with some books opting for Texans -2 on Monday night. Houston’s retooled offensive line could be without starting center Jake Andrews against this aggressive Buccaneers’ pass rush. The total opened at 44.5 points, a point shorter than the look-ahead total of 45.5 O/U.
Also see: full Monday Night Football odds
Chargers vs Raiders odds (Monday, 10:00 p.m. ET, ESPN)
Opening line
- Raiders +3
- Over/Under 43.5
- View full Chargers vs. Raiders odds and matchup
- Read our Chargers vs. Raiders picks and predictions
The line opened at the key number of 3, with the Chargers as a juiced favorite, and the spread has ping-ponged between 3 and 3.5. The total opened at 43.5 and climbed to as high as 47.5 before falling to 46.5.
Also see: full Monday Night Football odds
Best NFL bets this week
Looking for our favorite spread, total, and NFL prop bets for this week's action? Check out our best free NFL picks from the Covers staff!
Odds are correct at the time of publishing and are subject to change.
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