The NFL schedule is finally released! We now know what each team's matchups will be in this new 18-week season, including the game list for Week 5.
The NFL Week 5 matchups begin with a Thursday Night clash between the Rams and Seahawks, features an international game between the Jets and Falcons and is capped off by a Monday Night Football matchup between the Colts and Ravens.
Here is the list of all the NFL Week 5 matchups, times and opening spreads.
NFL Week 5 Odds
These are the opening NFL odds for Week 5, headlined by the Rams in a pick'em visiting the Seahawks and Kansas City favored by 4.5-points against Buffalo.
| Matchup | Time | Spread | Over/Under |
|---|---|---|---|
| Rams at Seahawks | Thurs, 8:20 p.m. ET | PK | 48 |
| Jets at Falcons* | Sun, 9:30 a.m. ET | Falcons -3 | 48 |
| Lions at Vikings | Sun, 1 p.m. ET | Vikings -8.5 | 48 |
| Saints at Washington | Sun, 1 p.m. ET | Washington +1.5 | 46.5 |
| Patriots at Texans | Sun, 1 p.m. ET | Texans +6 | 46.5 |
| Dolphins at Buccaneers | Sun, 1 p.m. ET | Buccaneers -7.5 | 50.5 |
| Packers at Bengals | Sun, 1 p.m. ET | Bengals +3 | 47.5 |
| Broncos at Steelers | Sun, 1 p.m. ET | Steelers -4.5 | 45 |
| Eagles at Panthers | Sun, 1 p.m. ET | Panthers -3 | 47.5 |
| Titans at Jaguars | Sun, 1 p.m. ET | Jaguars +2.5 | 48 |
| Browns at Chargers | Sun, 4:05 p.m. ET | Chargers +1.5 | 47.5 |
| Bears at Raiders | Sun, 4:05 p.m. ET | Raiders -3.5 | 46.5 |
| 49ers at Cardinals | Sun, 4:25 p.m. ET | PK | 46.5 |
| Giants at Cowboys | Sun, 4:25 p.m. ET | Cowboys -5.5 | 48.5 |
| Bills at Chiefs | Sun, 8:20 p.m. ET | Chiefs -4.5 | 54.5 |
| Colts at Ravens | Mon, 8:15 p.m. ET | Ravens -4 | 49 |
*This game will be played in London, England.
Odds courtesy of The SuperBook as of May 16, 2021
More weekly NFL odds content
- Week 1 odds
- Week 2 odds
- Week 3 odds
- Week 4 odds
- Week 6 odds
- Week 7 odds
- Week 8 odds
- Week 9 odds
- Week 10 odds
- Week 11 odds
- Week 12 odds
- Week 13 odds
- Week 14 odds
- Week 15 odds
- Week 16 odds
- Week 17 odds
- Week 18 odds
Where can I bet on the NFL?
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