NFL Week 3 Odds: Cowboys Slim Home Faves on MNF

With TNF behind us, we have turned the page to Sunday in Week 3 of NFL betting. This week's slate has several great matchups, including the Cowboys taking on the rival Eagles on Monday Night Football. Check the full Week 3 NFL betting odds below.

Last Updated: Sep 25, 2021 1:56 PM ET Read Time: 8 min

The NFL Week 3 odds are on the move as we’re just hours from kickoff on Sunday, headlined by a massive NFC matchup.

The Tampa Bay Buccaneers visit the Los Angeles Rams at 4:25 p.m. ET with the spread for this game jumping across the fence, from Rams -1 to Bucs -1.5 earlier in the week. Where will the late money move the spread and total?

We track Bucs vs. Rams and all the Week 3 NFL odds, from opening numbers to sharp action and public play. 

NFL odds for Week 3 are headlined by the undefeated Buccaneers visiting the 2-0 Rams as 1-point road underdogs, while the Cowboys are 4-point chalk in an NFC East showdown with the Eagles on Monday Night Football.

Matchup Time Spread Over/Under
Panthers at Texans Thurs, 8:20 p.m. ET Texans +8 43.5
Colts at Titans Sun, 1 p.m. ET Titans -4.5 47.5
Falcons at Giants Sun, 1 p.m. ET Giants -2.5 47
Chargers at Chiefs Sun, 1 p.m. ET Chiefs -6.5 54.5
Bengals at Steelers Sun, 1 p.m. ET Steelers -3 43
Bears at Browns Sun, 1 p.m. ET Browns -7 44
Ravens at Lions Sun, 1 p.m. ET Lions +7.5 50.5
Saints at Patriots Sun, 1 p.m. ET Patriots -2.5 43.5
Cardinals at Jaguars Sun, 1 p.m. ET Jaguars +7.5 51.5
Washington at Bills Sun, 1 p.m. ET Bills -7 45.5
Jets at Broncos Sun, 4:05 p.m. ET Broncos -10 42
Dolphins at Raiders Sun, 4:05 p.m. ET Raiders -3.5 44.5
Seahawks at Vikings Sun, 4:25 p.m. ET Vikings +2 54.5
Buccaneers at Rams Sun, 4:25 p.m. ET Rams +1.5 55
Packers at 49ers Sun, 8:20 p.m. ET 49ers -3 50.5
Eagles at Cowboys Mon, 8:15 p.m. ET Cowboys -3 52

Odds courtesy of DraftKings Sportsbook as of September 26, 2021

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Opening line

Texans +7, Over/Under 43.5

Why the line moved

UPDATE 8:10 A.M. ET, MONDAY SEPT. 20: Carolina opened as a touchdown favorite on the road in Houston and was quickly bet up to -7.5, due to the Texans’ QB situation. 

Starter Tyrod Taylor will miss Week 3 with a hamstring injury, leaving rookie Davis Mills under center on a short week of preparation. Of course, Houston still has Deshaun Watson on the roster and his status for Week 3 is foggy after a falling out with the franchise and multiple sexual assault accusations this offseason.  

The total for this game opened at 43.5 points.

Opening line

Titans -5, Over/Under 50

Why the line moved

UPDATE 7:40 A.M. ET, SUNDAY SEPT. 26: The Titans have slimmed from -5.5 to -4.5 with news that Colts QB Carson Wentz will start Sunday’s game despite suffering two sprained ankles in Week 2. 

Sportsbook operators are reporting contrasting betting splits with some books heavier on the Titans than others. Our unbiased Covers Consensus shows 67 percent of picks on Tennessee as of Sunday morning. 

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Opening line

Giants -3.5, Over/Under 48.5

Why the line moved

UPDATE 7:45 A.M. ET, SUNDAY SEPT. 26: DrafKings sportsbooks are reporting one-sided play on Atlanta, with 69 percent of bets and 66 percent of handle on the Falcons. This spread has slimmed from Atlanta +3.5 all the way to +2.5 as of Sunday morning, with operators dealing New York -2.5 at a pricier -115 or higher. 

Opening line

Chiefs -6.5, Over/Under 55.5

Why the line moved

UPDATE 7:50 A.M. ET, SUNDAY SEPT. 26: Depending on which side you like, you can shop around for Chargers +7 (-110) or Kansas City -6.5 (-115). 

WynnBET is reporting one-sided action on the host Chiefs, with almost 82 percent of spread handle and 69 percent of ticket count on KC. 

The total for this AFC West war is sitting at 54.5, down from 55.5 earlier in the week, despite a reported 81 percent of bet count on the Over.  

Opening line

Steelers -4.5, Over/Under 45

Why the line moved

UPDATE 7:55 A.M. ET, SUNDAY SEPT. 26: The Steelers are down as low as -2.5 (-115), moving from as high as -4.5 earlier in the week. Pittsburgh QB Ben Roethlisberger is expected to play through a pectoral injury.

Sportsbooks are reporting heavy action on the Steelers, despite those injury concerns. WynnBET sportsbooks have taken almost 75 percent of the money on Pittsburgh with more than 72 percent of ticket riding on the home side. Our Covers Consensus shows 62 percent of picks on Pittsburgh. 

Opening line

Browns -7.5, Over/Under 47

Why the line moved

UPDATE 8:00 A.M. ET, SUNDAY SEPT. 26: This spread dipped from Browns -7.5 to -7 and there are still some of those clean touchdown spreads out there. However, if you like Chicago you can shop and find the extra half-point hook on the underdog +7.5 (-115).

DraftKings sportsbooks are reporting 73 percent of the handle on Cleveland while 61 percent of bets are laying the points with the bang-up Browns. 

The total for this game is sitting as low as 44 points after coming down from the opener of 47, with 67 percent of the money on the total taking the Under.

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Opening line

Detroit +9, Over/Under 49.5

Why the line moved

UPDATE 8:05 A.M. ET, SUNDAY SEPT. 26: This spread was at different numbers at various books all week, but an overall market move now has the industry consensus of Baltimore -7.5 – down from as high as Ravens -9.

WynnBET is reporting over 70 percent of ticket count and handle on the spread is siding with Baltimore on the road and our Covers Consensus shows 69 percent of picks on the favorite – a tell-tale reverse line move which could indicate respected action and bigger bets are coming in on Detroit at home.

Opening line

Patriots -3, Over/Under 42.5

Why the line moved

UPDATE 8:20 A.M. ET, SUNDAY SEPT. 26: Action on the Saints has pushed this spread below the key number of a field goal, with some buyback on New England -2.5 bringing it back to Patriots -3. However, there are still some New England -2.5 (-120) spreads out there as of Sunday morning.

Our Covers Consensus is showing 57 percent of picks on the host Patriots, and sportsbook operators are drawing similar betting patterns. 

Opening line

Jaguars +7, Over/Under 52

Why the line moved

UPDATE 8:25 A.M. ET, SUNDAY SEPT. 26: Arizona opened as a touchdown favorite and quickly got bet up to -7.5 by Monday afternoon. This spread has flirted with Cardinals -8 at a few books but hasn’t strayed too far with buyback shrinking those spread to -7.5.

According to Covers Consensus, 76 percent of picks are behind the Cardinals while sportsbook operators, such as WynnBET, are reporting as much as 86 percent of bets on Arizona and 91 percent of handle on the road favorite.

Opening line

Bills -9.5, Over/Under 46.5

Why the line moved

UPDATE 8:30 A.M. ET, SUNDAY SEPT. 26: This is one of the biggest moves of Week 3, with Buffalo opened as big as -9.5 hosting Washington (bet up as high as -10) and slimming to -7 as of Sunday morning. 

DraftKings sportsbooks are reporting 80 percent of handle on the Bills while just 67 percent of ticket count is laying the lumber with his lofty spread. Our Covers Consensus shows 63 percent of picks on the home team. 

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Opening line

Broncos -11, Over/Under 41.5

Why the line moved

UPDATE 8:35 A.M. ET, SUNDAY SEPT. 26: With injuries on both sides of the ball for the Broncos, this spread has dwindled from Denver -11.5 to -10 as of Sunday morning, with some books dealing New York +10.5 (-120).

WynnBET is reporting over 75 percent of bets riding on the Broncos but the handle is a touch more spread out, with about 67 percent of money also on the host favorite. Covers Consensus shows 64 percent of picks on Denver as well. 

Opening line

Raiders -5.5, Over/Under 45.5

Why the line moved

UPDATE 8:40 A.M. ET, SUNDAY SEPT. 26: This spread has dropped a full two points since opening Las Vegas -5.5, despite Miami losing starting QB Tua Tagovailoa for the immediate future. Raiders QB Derek Carr is expected to play through an ankle injury.

Sportsbook are reporting one-sided betting patterns on Las Vegas, with DraftKings taking in 90 percent of bets on the home side. Covers Consensus numbers show 71 percent of picks on the Silver and Black. 

The total for this game opened 45.5 and dipped to 44, with a big split in total action versus ticket counts. WynnBET is reporting almost 64 percent of bets on the Over but 61 percent of the handle sitting on the Under, indicating sharp play and biggest wagers on the Under.

Opening line

Vikings +1, Over/Under 55

Why the line moved

UPDATE 8:45 A.M. ET, SUNDAY SEPT. 26: With Minnesota RB Dalvin Cook expected to miss Week 3, this spread went from Vikings +1 to +2. According to DraftKings sportsbooks, 72 percent of the money wagered on the spread is on Seattle while 81 percent of tickets written say Seahawks.

Opening line

Rams +1.5, Over/Under 54.5

Why the line moved

UPDATE 8:50 A.M. ET, SUNDAY SEPT. 26: After an early move over the fence from Rams -1 to Buccaneers -1, this spread is sitting at Tampa Bay -1.5 at most books domestic and international. Our Covers Consensus shows just 54 percent of picks on the Bucs while sportsbook operators are reporting a much heavier lean toward the reigning Super Bowl champs.

WynnBET has taken 73 percent of ticket on Tampa Bay as well as 78 percent of the spread handle. DraftKings sportsbooks are seeing similar patterns, with 80 percent of bets on Brady & Co. and 73 percent of the money on the visitors.

The total for this monster conference clash is sitting at 55.5 as of Sunday morning after a brief climb to 56 points stirred up buyback on the Under this weekend. Nearly 80 percent of the handle is on the Over while 80 percent of bets are banking on a high-scoring finish in Los Angeles.

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Opening line

49ers -4, Over/Under 48.5

Why the line moved

UPDATE 8:55 A.M. ET, SUNDAY SEPT. 26: The half-point hook on this Sunday Night Football spread is gone with midweek money on the underdog Packers moving the line to San Francisco -3 (-110). Our Covers Consensus shows 57 percent of picks on the Cheeseheads while books are reporting a heavier lean towards Green Bay, with 79 percent of tickets on the road underdog.

The total for this primetime game moved from as low as 48 points to as high as 50.5 as of Sunday morning. WynnBET has drawn more than 94 percent of the money on the Over with more than 80 percent of totals tickets on the Over as well.

Opening line

Cowboys -4, Over/Under 48.5

Why the line moved

UPDATE 9:00 A.M. ET, SUNDAY SEPT. 26: The Cowboys have dropped from -4 to as low as -3 (-120) for the Monday Night Football finale to Week 3. 

This move comes despite books reporting the bulk of betting action on Dallas, with DraftKings pulling in 67 percent of handle and 66 percent of tickets on the home side – a clear indication that respected wagers and bigger action is taking the underdog Eagles.

The total for this NFC East rivalry opened at 51.5 points and has stayed steady around that number, with brief moves to 52 before slimming back down. WynnBET is seeing an interesting split in ticket count versus Over/Under handle, with nearly 86 percent of the money on the Under but 56 percent of bets on the Over as of Sunday morning.

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