The Jacksonville Jaguars head to Nissan Stadium as heavy 10.5-point road favorites against the Tennessee Titans in Week 10, with kickoff set for 1 p.m. ET on FOX.
My Jaguars vs. Titans predictions and NFL picks expect the visitors to win easily, and as we all know, blowouts are where Overs die.
Here's my breakdown and expert NFL best bets for Nov. 15.
TOP Pick
Jaguars vs Titans prediction today: Under 46.5
The Under is my preferred play in this game down to 44.5.
The Jacksonville Jaguars have allowed the second-fewest points per game (15.1) and third-lowest EPA per play to rank third in defensive DVOA.
It's a similar story on offense with the Jags scoring the fourth-most points per game (28.6) and generating the fifth-highest EPA per play to rank fifth in offensive DVOA.
Jacksonville won't hit this Over on its own, though, and blowouts are where Overs go to die.
With the Tennessee Titans averaging the third-fewest plays per game while ranking 28th in points per game (18.0) and 25th in offensive DVOA, I'm expecting the Jags to hold the Titans in check to keep this total Under the number.
COVERS INTEL: The Jacksonville Jaguars have allowed the second-fewest points per drive, and the Tennessee Titans have scored the fifth-fewest points per drive.
Jaguars vs Titans combo
Jacksonville is superior on both sides of the ball and has covered the spread in 15 of its past 20 games (+9.60 Units / 44% ROI).
The Titans have allowed seven different quarterbacks to reach double-digit rushing yards, and Jags QB Trevor Lawrence is a capable rusher, with 79 yards on the season and 3.14 yards after contact per attempt.
Turning to Jacksonville No. 1 running back Bhayshul Tuten, he's scored in each of the past three games to climb to seven touchdowns for the season, and he's also handled 51.4% of the red-zone carries through eight games for the Jags.
Jaguars vs Titans combo
- Jaguars -10.5
- Trevor Lawrence 10+ rushing yards
- Bhayshul Tuten anytime touchdown
Jaguars vs Titans touchdown scorer: Bhayshul Tuten
This touchdown prop is in play to 58%.
It's not just Tuten's role that has my attention this week. He boasts a rock-solid 3.65 YCO/A and 98.5 PFF elusive rating, and he's equally dangerous through the air with 15.1 yards after the catch per reception.
The Titans rank 29th in run defense DVOA, too, so the matchup checks out.
For more Week 10 touchdown angles, including Jaguars tight end Nate Boerkircher, see our NFL anytime touchdown picks for Week 10.
Jaguars vs Titans player prop: Tony Pollard 16+ rush attempts
This prop is in play up to 54% because the Titans have leaned on running back Tony Pollard all season, and he’s handled 16 or more carries in five of the past six games with an average of 18.7 rushes per week.
Additionally, I’m confident Tennessee will remain committed to the run because the Titans are 24th in pass rate over expected, and attacking on the ground will help protect QB Cam Ward from a Jacksonville pass rush ranked fifth in quarterback-knockdown percentage.
Want more NFL player props? Check out our NFL player prop projections!
Jaguars vs Titans market trend
Here's how trusted traders at Kalshi are dealing on today’s matchup. Follow the smart money via the widget below to help inform your Jaguars vs. Titans prediction.
- Top picks: 55-46, +10.44 units
- Combos: 2-21, -10.1 units
Jaguars vs Titans odds today
For help understanding probabilities, see our odds calculator.
- Spread: Jaguars -10.5 | Titans +10.5
- Over/Under: Over 46.5 (49%) | Under 46.5 (52%)
- Moneyline: Jaguars 84% | Titans 17%
For the full slate of NFL matchups, check out our NFL odds board!
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Jaguars vs Titans weather
The forecast calls for sunny skies, 52°F temperatures, and light 5 mph winds Sunday afternoon.
Check out our NFL weather page for up-to-date info on every matchup.
Jaguars vs Titans trend to know
The Jacksonville Jaguars have covered the spread in 15 of their last 20 games (+9.60 Units / 44% ROI). Find more NFL trends for Jaguars vs. Titans.
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How to watch Jaguars vs Titans
| Location | Nissan Stadium, Nashville, Tenn. |
| Date | Sunday, Nov. 15, 2026 |
| Kickoff | 1 p.m. ET |
| TV | FOX |
Jaguars vs Titans latest injuries
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