The Seattle Seahawks are -6.5-point road favorites over the Las Vegas Raiders in rookie quarterback Fernando Mendoza’s first career start, kicking off at 4:05 p.m. ET at Allegiant Stadium on Sunday, Nov. 15.
My favorite Seahawks vs. Raiders prediction and NFL picks expect the Seattle defense and running back Zach Charbonnet to lead the way to a lopsided win in Sin City.
TOP Pick
Seahawks vs Raiders prediction: Seahawks -6.5
The Seattle Seahawks are my recommended side to -7.5.
Seattle ranks second in defensive DVOA while allowing the fifth-lowest EPA per play and generating pressure at the second-highest rate.
It’s a nightmare scenario for Las Vegas Raiders rookie quarterback Fernando Mendoza in his first career start.
Of course, the Las Vegas defense ranks last in DVOA and has allowed the highest EPA per play over the past seven weeks.
Simply put, the Seahawks are better on both sides of the ball and still have work to do to secure a postseason berth, so I don't expect Seattle to let Las Vegas hang around Sunday afternoon.

Seahawks vs Raiders combo
The Raiders have surrendered nine touchdowns to opposing running backs over their past six games and allowed the highest EPA per rush to rank last in run defense DVOA during the stretch, making this a cushy matchup for Seattle running back Zach Charbonnet.
He showed off in Week 9 with a high-end 3.75 yards after contact per attempt and an 110 PFF elusive rating, finishing with 77 rushing yards on 16 carries.
Seahawks vs Raiders combo
- Seahawks -6.5
- Zach Charbonnet 60+ rushing yards
- Zach Charbonnet anytime touchdown
Seahawks vs Raiders touchdown scorer: Zach Charbonnet
I recommend Charbonnet to find the end zone up to 50%.
He scored 21 times across 33 games over the past two years, and Charbonnet played 56% of the offensive snaps last week in his second game back from the reserve/PUP list.
Plus, in addition to the noted Vegas struggles against the run, it's also allowed red-zone trips to turn into touchdowns at the fifth-highest rate.
- Top picks: 55-46, +10.44 units
- Combos: 2-21, -10.1 units
Seahawks vs Raiders odds
For help understanding probabilities, see our odds calculator.
- Spread: Seahawks -6.5 | Raiders +6.5
- Over/Under: Over 40.5 (50%) | Under 40.5 (51%)
- Moneyline: Seahawks 73% | Raiders 28%
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Seahawks vs Raiders weather
Allegiant Stadium is a fully enclosed, climate-controlled dome.
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Seahawks vs Raiders trend to know
The Las Vegas Raiders have won only two of their last 11 home games (-8.15 Units / -61% ROI). Find more NFL betting trends for Seahawks vs. Raiders.
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How to watch Seahawks vs Raiders
| Location | Allegiant Stadium, Las Vegas |
| Date | Sunday, Nov. 15, 2026 |
| Kickoff | 4:05 p.m. ET |
| TV | CBS |
Seahawks vs Raiders latest injuries
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