Rams vs Cardinals Prediction, Picks & Odds: NFL Week 10

Jason Logan: Senior Betting Analyst at Covers
Jason Logan • Senior Betting Analyst 21+ years betting experience
Updated: Nov 14, 2026 , 11:05 AM ET • 4 min read

The Cardinals feed rookie QB Carson Beck to the Rams' two-headed pass-rushing monster of Myles Garrett and Aaron Donald. Jason Logan gives his NFL picks for this NFC West war.

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Match starts: 23 hrs
Rams vs Cardinals Prediction, Picks & Odds. Los Angeles Rams defensive end Myles Garrett NFL
Photo By - Reuters Connect. Los Angeles Rams defensive end Myles Garrett.

At least Carson Beck will have a crazy story to tell his kids when they ask about his first NFL start... if he survives.

The Arizona Cardinals must march the rookie quarterback out to face the Los Angeles Rams (-9.5) and their gruesome twosome of Aaron Donald and Myles Garrett in Week 10.

My Rams vs. Cardinals predictions sort out the shifting sands in the NFC West, highlighting some of my best NFL picks for Nov. 15.

 TOP Pick
Rams vs Cardinals prediction: Under 39.5

This total has dropped a touchdown since opening last Sunday night. And it’s not just the Arizona Cardinals’ QB quandary dragging the number down. 

Both teams will be without their WR1s, as Los Angeles Rams wideout Puka Nacua and Arizona standout Michael Wilson suffered injuries in Week 9. 

The cupboard is very bare for Carson Beck, with no Wilson or Kendrick Bourne to throw to, nor does he have RBs Jeremiyah Love and James Conner to help shoulder the offensive load.

As for the Rams, their snake-bitten lineup is looking ahead to a much-needed bye in Week 11. With a spread this size, I expect Los Angeles to try and get up quick and then slow things down in the second half to avoid further casualties. 

Los Angeles has seen a significant shift in play calling the past three games, upping its run rate from 36% in the first six outings to 48.5% during this current three-game win streak.

That’s slimmed the Rams’ yards per play from 5.9 to 5.2 but upped their average time of possession.

Covers COVERS INTEL: Under Brissett, Arizona was using the fifth-fewest seconds per play clock while running no-huddle at the sixth-highest rate. That pace slowed with the QB switch to Minshew and will dip again with a rookie at the wheel.

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Rams vs Cardinals combo

A lack of weapons, a rookie QB, and a Rams team trying to get to the bye week without suffering any more hurt. These are all reasons Arizona and Los Angeles stay below the total in Week 10.

Blake Corum has scored a touchdown in four straight games, including a receiving TD vs. Arizona in Week 6. He’ll get a lot of love in the second half, given the big spread and game script.

Tyler Allgeier is now the Cardinals RB1 and is getting a ton of work, with injuries up and down this offense. He’s drawn at least three targets in the past three games, and with a rookie QB under center, Allgeier will be a favorite option on short, safe throws.

Rams vs Cardinals combo

  • Under 39.5
  • Blake Corum touchdown
  • Tyler Allgeier 10+ receiving yards

Rams vs Cardinals touchdown scorer: Blake Corum 

Blake Corum has enjoyed the Rams’ three-game winning streak. He’s seen a spike in carries and has struck for a touchdown in each of those outings.

Corum does the bulk of his damage in the second half, providing relief for RB1 Kyren Williams, with four of his five total TDs this season coming in the closing 30 minutes. 

His lone first-half strike was a 15-yard touchdown reception in the Week 6 upset loss to Arizona.

Given the beefy spread and the game-script attached to it, Corum will continue to see touches in the final two frames on Sunday. His touchdown forecasts range from 31% to 50% in Week 10.

Jason Logan's 2026 Transparency Record
  • Top picks: 13-11, +0.19 units
  • Combos: 0-24, -24.0 units
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Rams vs Cardinals odds

For help understanding probabilities, see our odds calculator.

  • Spread: Rams -9.5 | Cardinals +9.5
  • Over/Under: Over 39.5 (50%) | Under 39.5 (51%)
  • Moneyline: Rams 80% | Cardinals 20%

For the full slate of NFL matchups, check out our NFL odds board!


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Rams vs Cardinals weather

State Farm Stadium has a retractable roof and will open if conditions are nice in Glendale.

Check out our NFL weather page for up-to-date info on every matchup.

Rams vs Cardinals trend to know

Under Sean McVay, the Rams are 9-1 SU and 6-4 ATS as road favorites of more than a touchdown (since 2017). Find more NFL betting trends for Rams vs. Cardinals.

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How to watch Rams vs Cardinals

Location State Farm Stadium, Glendale AZ
Date Sunday, Nov. 15, 2026
Kickoff 4:05 p.m. ET
TV FOX

Rams vs Cardinals latest injuries

Check out our NFL injuries page for updates on every team. 

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Pages related to this topic

Jason Logan Senior Industry Analyst Covers.com
Senior Betting Analyst

In his 20 years with Covers, lead NFL betting analyst Jason Logan has seen it all and bet it all. Through the wild west of early Internet gambling to lobbying for legalized sports betting to our brave new wagering world, Jason has been a consistent source of actionable info and entertainment for squares and sharps alike.

Since joining the Covers team back in 2005, he honed his handicapping skills to provide audiences with the most thorough insights, blending traditional capping methods with advanced modelling and predictive analysis. Jason has studied the ins and outs of the sports betting business, learning from some of the most successful gamblers in the industry and the biggest sportsbook operators on the planet.

He is under center for Covers during NFL season as our top NFL expert, taking the points in his infamous NFL Underdogs column and representing the Covers Community at the Super Bowl. While he lives for football season, Jason's first love is basketball and that shows in his in-depth NBA, NCAA, and WNBA betting breakdowns.

On top of being a mainstay in media from coast to coast at stations like WPIX, PHL17, Fox 5 San Diego, WGNO, TSN, SportsNet, ESPN Radio, Jason's analysis has also been featured in USA Today, MSNBC, ESPN, the Wall Street Journal, CBS, Bloomberg, the L.A. Times, the New York Times and other major publications. You can also find JLo stuffing all the top picks and predictions he can into 10 minutes as the host of Covers' flagship podcast, The Sharp 600.

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