My Texas Tech vs. Oklahoma State predictions for tonight's Big 12 showdown believe the Cowboys will win and cover, and that Boone Pickens Stadium will be turned into a fireworks factory.
Oklahoma State is a 3.5-point favorite at Kalshi ahead of a 9:30 p.m. ET kickoff on ESPN.
See all of our Week 11 college football picks for Saturday, Nov. 14, plus our Week 11 Top Picks and Brad Powers' Week 11 predictions.
TOP PICK
Who will win Texas Tech vs Oklahoma State today: Oklahoma State -3.5
I'll take the Oklahoma State Cowboys -3.5, up to -4.5, as I expect the public to gravitate toward the higher-ranked, reigning Big 12 champion catching 3-and-the-hook.
However, the underlying numbers favor Oklahoma State.
The Cowboys rank 16th nationally in schedule-adjusted net EPA per play, compared with 32nd for the Texas Tech Red Raiders, per GameOnPaper.com. And while laying -3.5 is never comfortable, it's less intimidating in a game with a 70-plus-point total, where one score represents a smaller share of the expected scoring.
Oklahoma State also owns the best win on either resume, upsetting a healthy Oregon team in Week 2 when the Ducks were 24-point favorites.
See our college football picks against the spread for more Week 11 sides.

Texas Tech vs Oklahoma State Over/Under pick today: Over 72.5
Give me the Over 72.5, up to 74.5, because the market is practically begging you to take the Under on one of Week 11's highest totals.
I'm not falling for it. Texas Tech and Oklahoma State are a combined 11-1 to the Over in conference play, and neither offense wastes time. The Red Raiders rank ninth nationally in seconds per play, while the Cowboys are 16th.
That pace means more possessions and more opportunities to score, which matters when both teams have repeatedly cleared their totals in conference play. This has track meet written all over it, and I don't think the market can hang a number high enough.
See our college football Over/Under picks for more Week 11 totals.
Texas Tech vs Oklahoma State prop: Oklahoma State -2.5 1H
I'm taking Oklahoma State -2.5 in the first half, up to -3. The Cowboys' explosive passing attack will put the Red Raiders on their heels early at Boone Pickens Stadium.
Per GameOnPaper, Oklahoma State's offensive explosive play rate sits in the 81st percentile nationally, while Texas Tech's defense is in the 38th percentile. Mestemaker leads the Big 12 in passer efficiency rating, and the Red Raiders rank 13th in opponent completion percentage and 15th in passing yards allowed per game.
Better yet, Texas Tech is 2-7 against the spread in first halves this season, including 0-3 ATS on the road.
Texas Tech vs Oklahoma State combo
Good luck keeping this game under control once the Cowboys start hitting explosive plays. Texas Tech has the offense to trade punches, but its defense is a liability against Drew Mestemaker and Oklahoma State's passing attack.
That should put the Red Raiders in catch-up mode early, which only adds fuel to a potential shootout. Ultimately, Texas Tech can do its part offensively without ruining Oklahoma State's chances of covering.
Give me a fast start and four quarters of fireworks.
See our college football Top 25 predictions for more on today's marquee matchups.
Texas Tech vs Oklahoma State combo
- Cowboys -3.5
- Over 72.5
- Oklahoma State -2.5 1H
Texas Tech vs Oklahoma State market trends
Here's how trusted traders at Kalshi are dealing on today’s matchup. Follow the smart money via the widget below to help inform your Texas Tech vs. Oklahoma State prediction.
- Top picks: 18-24, -7.40 units
- Combos: 4-38, -21.30 units
More Week 11 college football picks and predictions
- Week 11 college football Top Picks for Saturday, Nov. 14: Top pick from every game preview
- College football predictions Week 11: Brad Powers' CFB picks
- Week 11 college football AI predictions
- College football Top 25 predictions Week 11: watchability ratings and picks
- College football Week 11 picks against the spread
- College football Week 11 moneyline picks
- College football Over/Under picks: Week 11
- College football underdog picks and upset predictions: Week 11
- College football player props: Week 11
- Our favorite college football Group of 6 predictions: Week 11
Texas Tech vs Oklahoma State odds tonight
For help understanding probabilities, see our odds calculator.
- Spread: Texas Tech +3.5 | Oklahoma State -3.5
- Over/Under: Over 73.5 (53%) | Under 73.5 (52%)
- Moneyline: Texas Tech 42% | Oklahoma State 63%
Follow the Texas Tech vs. Oklahoma State market prices on Kalshi up to kickoff. See our college football moneyline picks for more win probabilities.
See our college football odds board for the full slate of college football matchups.
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Texas Tech vs Oklahoma State weather
Tonight's forecast in Stillwater calls for temperatures around 47°F, winds near 11 mph, and a 47% chance of rain.
See our college football weather page for up-to-date info on every matchup.
Texas Tech vs Oklahoma State trend to know
The Cowboys are 5-1 ATS in Big 12 games this season. Find more college football betting trends for Texas Tech vs. Oklahoma State, and see our college football AI predictions.
or our BET99 promo code COVERS99 if you're in Canada.
How to watch Texas Tech vs Oklahoma State tonight
| Location | Boone Pickens Stadium, Stillwater, Okla. |
| Date | Saturday, Nov. 14, 2026 |
| Kickoff | 9:30 p.m. ET |
| TV | ESPN |
Texas Tech vs Oklahoma State latest injuries
See our college football injuries page for updates on every team.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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