The No. 19 Ole Miss Rebels visit the Oklahoma Sooners at Gaylord Family — Oklahoma Memorial Stadium in Week 11 for a massive clash.
My top Ole Miss vs. Oklahoma predictions and free college football picks expect the Sooners' surging defense to officially extinguish the Rebels' slim playoff hopes while keeping this rescheduled tilt comfortably Under the number ahead of today's 1 p.m. ET kickoff on SEC Network.
TOP PICK
Who will win Ole Miss vs Oklahoma Sunday: Oklahoma -1.5
Playable to 54%.
Following a promising start to the 2026 campaign, Ole Miss has done potentially irreversible damage to its playoff hopes with two losses in the last three weeks.
Last weekend, Georgia dominated Ole Miss from the opening kickoff (91.9% win probability at the end of the first quarter), to the point that head coach Pete Golding told his team at the half that he wasn't worried about the score — he only wanted his players to focus on putting good effort on tape in the final two quarters.
Ole Miss' defense has been nowhere to be found against quality opponents, most recently getting outgained 481-252 at home by Georgia last weekend.
Oklahoma's strength is its stop unit, but John Mateer & Co. are also coming off a 10-for-18 showing on third down against Florida, dominating time of possession in the process. They should have a field day against the Rebels in Norman.
See our college football picks against the spread for more Week 11 sides.
COVERS INTEL: Ole Miss quarterback Trinidad Chambliss has struggled to a 4-to-5 TD-to-INT ratio across his last three games. He's been increasingly unproductive when under duress — completing only 37.5% of his pass attempts when pressured this season.
Ole Miss vs Oklahoma Over/Under pick Sunday: Under 49.5
Playable to 54%.
The Sooners dominated Florida last weekend, holding them to 203 yards of total offense and only 11 first downs. They had a similarly dominant showing against No. 15 Kentucky earlier this year, too, limiting them to 230 yards of offense.
Oklahoma generated a 46.2% pressure rate last weekend against Florida. If the Sooners can get anywhere close to that number again in Week 11, Chambliss' struggles will continue, making it difficult for Ole Miss to move the ball consistently.
See our college football Over/Under picks for more Week 11 totals.
Ole Miss vs Oklahoma combo
Playable to 28%.
Oklahoma is coming off a 23-7 win over Florida and has been competitive in lower-scoring matchups against No. 1 Texas (27-24 win), No. 15 Kentucky (21-13 loss), and Michigan (17-10).
However, the Sooners have struggled to keep pace in games where the combined score approaches 60 points.
Taking OU on the side and the Under is a correlated combo in this SEC showdown. See our college football Top 25 predictions for more on this matchup.
Ole Miss vs Oklahoma combo
- Oklahoma moneyline
- Under 49.5
- Top picks: 10-8 +1.40 units
- Combos: 8-12, +6.57 units
More Week 11 college football picks and predictions
- Week 11 college football Top Picks for Saturday, Nov. 14: Top pick from every game preview
- College football predictions Week 11: Brad Powers' CFB picks
- Week 11 college football AI predictions
- College football Top 25 predictions Week 11: watchability ratings and picks
- College football Week 11 picks against the spread
- College football Week 11 moneyline picks
- College football Over/Under picks: Week 11
- College football underdog picks and upset predictions: Week 11
- College football player props: Week 11
- Our favorite college football Group of 6 predictions: Week 11
Ole Miss vs Oklahoma odds Sunday
For help understanding probabilities, see our odds calculator.
- Spread: Ole Miss -1.5 | Oklahoma +1.5
- Over/Under: Over 49.5 (49%) | Under 49.5 (52%)
- Moneyline: Ole Miss 50% | Oklahoma 51%
Check the latest college football odds for more on today's Ole Miss vs. Oklahoma matchup, and see our college football moneyline picks for more win probabilities.
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Ole Miss vs Oklahoma weather
The forecast for Sunday's game between Ole Miss and Oklahoma looks uneventful.
Cooler temperatures and wind gusts could have a minimal impact on downfield passing, but there is no precipitation expected, which should result in a relatively clean game.
See our college football weather page for up-to-date info on every matchup.
Ole Miss vs Oklahoma trend to know
Oklahoma has hit the moneyline in seven of its last 12 games (+1.65 Units / 4% ROI). Find more college football betting trends for Ole Miss vs. Oklahoma, and see our college football AI predictions.
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How to watch Ole Miss vs Oklahoma
| Location | Memorial Stadium, Norman, Okla. |
| Date | Sunday, Nov. 15, 2026 (moved from Saturday, Nov. 14) |
| Kickoff | 1 p.m. ET (moved from 4:15 p.m. ET) |
| TV | SEC Network |
Ole Miss vs Oklahoma latest injuries
See our college football injuries page for updates on every team.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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