The 29th edition of the Holy War takes center stage Saturday as Boston College visits Notre Dame Stadium, where the Fighting Irish are 30.5-point favorites with a game total of 53.5.
Notre Dame is expected to cruise, but my Boston College vs. Notre Dame prediction looks beyond the massive spread to uncover a few betting angles in this historic rivalry. Kickoff is set for 3:30 p.m. ET on NBC and Peacock.
Explore more college football picks for Saturday, Nov. 14, check the latest Boston College vs. Notre Dame odds on Kalshi, where the Irish carry a 98% win probability, or dive into our Week 11 Top Picks and Brad Powers' Week 11 predictions.
TOP PICK
Who will win Boston College vs Notre Dame today: Notre Dame -30.5
I'll lay the lumber with the Notre Dame Fighting Irish -30.5, up to -32.5.
Notre Dame has an epic edge in the trenches over the Boston College Eagles, one of the most predictive areas of football handicapping. The Fighting Irish's offensive line owns the best sack rate in the country, while BC ranks 129th in front-seven havoc rate allowed, according to College Football Charts.
That mismatch gets even uglier, as the Eagles have one of the country's worst passing attacks, and nobody has averaged 4.5 yards per carry against Notre Dame this season.
BC should live in third-and-long, letting the Fighting Irish pin their ears back and tee off on the quarterback.
See our college football picks against the spread for more Week 11 sides.

Boston College vs Notre Dame Over/Under pick today: Under 53.5
The Under 53.5 is tradable down to 52.5 because blowouts are where Overs go to die, and I don't see Boston College contributing much to the scoreboard.
Notre Dame has held six opponents to 13 points or fewer, and every one of them ranks higher than BC in schedule-adjusted offensive EPA per play, according to GameOnPaper.com. The Eagles have also stayed Under their team total in three of their last five road games.
Neither offense is in a hurry. Boston College ranks 84th nationally in seconds per play, and Notre Dame is 117th. With chilly conditions expected, the Irish should control the clock while BC struggles to sustain drives.
See our college football Over/Under picks for more Week 11 totals.
Boston College vs Notre Dame combo
There's a pretty specific way this game needs to unfold: Notre Dame comes out swinging, builds a ridiculous lead, and spends the second half trying to get everyone home in one piece.
However, with this payout, it's worth trying to fit this combo into a tight window.
Boston College doesn't have the offense to force the Irish to keep their foot on the gas, which makes an early scoring burst followed by a whole lot of clock-killing doable.
If the Eagles sneak onto the scoreboard before things get ugly, even better. That's the kind of blowout I'm targeting here.
See our college football Top 25 predictions for more on today's marquee matchups.
Boston College vs Notre Dame combo
- Fighting Irish -30.5
- Under 53.5
- Over 13.5 first quarter
Boston College vs Notre Dame prop: Over 13.5 first quarter
Granted, this is more of a combo leg to boost my payout, but I'll play the Over 13.5 first quarter up to 58%.
It fits my game script: Notre Dame pummels Boston College early before taking its foot off the gas in the second half. Furthermore, the Fighting Irish have gone Over the total in eight of their last 12 games dating back to last season.
BC's best chance to score might come early, before Notre Dame's defense locks in. Perhaps the Eagles even pull out a trick play or two before this game gets out of hand.
Boston College vs Notre Dame smart money
Notre Dame is an overwhelming 98% favorite on Kalshi, but the smart-money activity tells a different story against the spread. One trader with more than $5 million in lifetime wagers placed $2,000 on Boston College +29.5 at 51¢, suggesting some confidence that the Eagles can keep the margin below 30 points despite the Fighting Irish's massive moneyline advantage.
- Top picks: 18-24, -7.40 units
- Combos: 4-38, -21.30 units
More Week 11 college football picks and predictions
- Week 11 college football Top Picks for Saturday, Nov. 14: Top pick from every game preview
- College football predictions Week 11: Brad Powers' CFB picks
- Week 11 college football AI predictions
- College football Top 25 predictions Week 11: watchability ratings and picks
- College football Week 11 picks against the spread
- College football Week 11 moneyline picks
- College football Over/Under picks: Week 11
- College football underdog picks and upset predictions: Week 11
- College football player props: Week 11
- Our favorite college football Group of 6 predictions: Week 11
Boston College vs Notre Dame odds today
For help understanding probabilities, see our odds calculator.
- Spread: Boston College +30.5 | Notre Dame -30.5
- Over/Under: Over 53.5 (52%) | Under 53.5 (53%)
- Moneyline: Boston College 3% | Notre Dame 98%
Follow the Boston College vs. Notre Dame market prices on Kalshi up to kickoff. See our college football moneyline picks for more win probabilities.
See our college football odds board for the full slate of college football matchups, including our Boston College vs. Notre Dame matchup.
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Boston College vs Notre Dame weather
The forecast calls for temperatures in the mid-40s, winds around 8 mph, and a 54% chance of rain.
See our college football weather page for up-to-date info on every matchup.
Boston College vs Notre Dame trend to know
The Fighting Irish have covered six of their last seven home games as 21-point favorites or greater since 2025. Find more college football betting trends for Boston College vs. Notre Dame, and see our college football AI predictions.
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How to watch Boston College vs Notre Dame
| Location | Notre Dame Stadium, South Bend, Ind. |
| Date | Today, Saturday, Nov. 14, 2026 |
| Kickoff | 3:30 p.m. ET |
| TV | NBC, Peacock |
Boston College vs Notre Dame latest injuries
See our college football injuries page for updates on every team.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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