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Best NFL Picks Today

Find the best NFL bets today - Sept. 22, 2026. Free expert and computer picks for every NFL game.

New Computer Picks powered by Odds Shark

Predicted Score

ATL logo
ATL
ATL

20.95 @ 25.66

GB
GB logo
GB

Falcons vs Packers · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

ATL logo
ATL
ATL

20.95

+6.5 -112

o43.5 -124

+240

GB logo
GB
GB

25.66

-6.5 -105

u44.5 -109

-270

Kansas City @ Miami
Matchup Stats

Predicted Score

KC logo
KC
KC

25.82 @ 16.96

MIA
MIA logo
MIA

Chiefs vs Dolphins · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

KC logo
KC
KC

25.82

-10.5 -125

o45.5 -115

-750

MIA logo
MIA
MIA

16.96

+10.5 -105

u46.5 -110

+575

Top Projection Rashee Rice Score a Touchdown (Yes: +190)
+190
Carolina @ Cleveland
Matchup Stats

Predicted Score

CAR logo
CAR
CAR

21.06 @ 19.57

CLE
CLE logo
CLE

Panthers vs Browns · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

CAR logo
CAR
CAR

21.06

+0.0 -155

o41.5 -110

-145

CLE logo
CLE
CLE

19.57

+2.5 +105

u42.5 -112

+130

Top Projection Darren Waller Score a Touchdown (Yes: +600)
+600
Tennessee @ N.Y. Giants
Matchup Stats

Predicted Score

TEN logo
TEN
TEN

17.18 @ 20.25

NYG
NYG logo
NYG

Titans vs Giants · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

TEN logo
TEN
TEN

17.18

+3.5 -124

o40.0 -112

+140

NYG logo
NYG
NYG

20.25

-3.5 +105

u40.5 -109

-155

Top Projection Jaxson Dart Score a Touchdown (Yes: +175)
+175
New England @ Jacksonville
Matchup Stats

Predicted Score

NE logo
NE
NE

21.57 @ 23.36

JAC
JAC logo
JAC

Patriots vs Jaguars · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

NE logo
NE
NE

21.57

+3.5 -125

o45.0 -110

+140

JAC logo
JAC
JAC

23.36

-3.5 +105

u45.5 -108

-152

Top Projection Hunter Henry Score a Touchdown (Yes: +350)
+350
L.A. Chargers @ Buffalo
Matchup Stats

Predicted Score

LAC logo
LAC
LAC

20.30 @ 26.71

BUF
BUF logo
BUF

Chargers vs Bills · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

LAC logo
LAC
LAC

20.30

+7.5 -120

o50.0 -110

+300

BUF logo
BUF
BUF

26.71

-7.5 +100

u50.5 -115

-334

Top Projection Justin Herbert o20.5 Rushing Yards (+100)
o19.5-109
N.Y. Jets @ Detroit
Matchup Stats

Predicted Score

NYJ logo
NYJ
NYJ

19.60 @ 29.76

DET
DET logo
DET

Jets vs Lions · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

NYJ logo
NYJ
NYJ

19.60

+6.5 -102

o47.5 -115

+270

DET logo
DET
DET

29.76

-6.5 -110

u48.5 -115

-300

Top Projection Garrett Wilson o60.5 Receiving Yards (-115)
o60.5-115
Houston @ Indianapolis
Matchup Stats

Predicted Score

HOU logo
HOU
HOU

22.78 @ 23.06

IND
IND logo
IND

Texans vs Colts · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

HOU logo
HOU
HOU

22.78

-2.5 -115

o43.0 -112

-142

IND logo
IND
IND

23.06

+2.5 +100

u43.5 -106

+130

Seattle @ Washington
Matchup Stats

Predicted Score

SEA logo
SEA
SEA

20.92 @ 16.57

WAS
WAS logo
WAS

Seahawks vs Commanders · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

SEA logo
SEA
SEA

20.92

-6.5 -120

o40.0 -110

-305

WAS logo
WAS
WAS

16.57

+6.5 +102

u40.5 -110

+265

Cincinnati @ Pittsburgh
Matchup Stats

Predicted Score

CIN logo
CIN
CIN

25.63 @ 21.83

PIT
PIT logo
PIT

Bengals vs Steelers · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

CIN logo
CIN
CIN

25.63

-3.5 -105

o42.5 -110

-185

PIT logo
PIT
PIT

21.83

+3.5 -105

u42.5 -107

+160

Top Projection Aaron Rodgers Score a Touchdown (Yes: +1500)
+1800
Arizona @ San Francisco
Matchup Stats

Predicted Score

ARI logo
ARI
ARI

20.92 @ 27.28

SF
SF logo
SF

Cardinals vs 49ers · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

ARI logo
ARI
ARI

20.92

+8.5 -109

o47.5 -110

+370

SF logo
SF
SF

27.28

-8.5 -105

u48.5 -115

-400

Top Projection Trey McBride Score a Touchdown (Yes: +280)
+280
Minnesota @ Tampa Bay
Matchup Stats

Predicted Score

MIN logo
MIN
MIN

19.90 @ 21.10

TB
TB logo
TB

Vikings vs Buccaneers · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

MIN logo
MIN
MIN

19.90

-1.5 -105

o42.0 -110

-120

TB logo
TB
TB

21.10

+1.5 -106

u43.0 -115

+105

Top Projection Baker Mayfield Score a Touchdown (Yes: +650)
+650
Baltimore @ Dallas
Matchup Stats

Predicted Score

BAL logo
BAL
BAL

26.84 @ 27.52

DAL
DAL logo
DAL

Ravens vs Cowboys · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

BAL logo
BAL
BAL

26.84

-2.5 -125

o52.5 -108

-155

DAL logo
DAL
DAL

27.52

+2.5 +105

u52.5 -107

+135

Top Projection Jake Ferguson o26.5 Receiving Yards (-113)
o26.5-113
Las Vegas @ New Orleans
Matchup Stats

Predicted Score

LV logo
LV
LV

21.37 @ 26.29

NO
NO logo
NO

Raiders vs Saints · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

LV logo
LV
LV

21.37

+3.5 -119

o43.5 -115

+160

NO logo
NO
NO

26.29

-3.5 +102

u44.5 -127

-164

Top Projection Michael Mayer Score a Touchdown (Yes: +700)
+700
L.A. Rams @ Denver
Matchup Stats

Predicted Score

LA logo
LA
LA

24.00 @ 23.06

DEN
DEN logo
DEN

Rams vs Broncos · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

LA logo
LA
LA

24.00

-2.5 -110

o45.5 -108

-135

DEN logo
DEN
DEN

23.06

+2.5 -105

u45.5 -108

+120

Top Projection Jaylen Waddle Score a Touchdown (Yes: +190)
+190
Philadelphia @ Chicago
Matchup Stats

Predicted Score

PHI logo
PHI
PHI

21.99 @ 19.21

CHI
CHI logo
CHI

Eagles vs Bears · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

PHI logo
PHI
PHI

21.99

-3.5 +100

o41.5 -110

-180

CHI logo
CHI
CHI

19.21

+3.5 -120

u43.5 -110

+185

Top Projection Colston Loveland o25.5 Receiving Yards (-115)
o25.5-115
Atlanta Falcons image thumbnail ATL @ Green Bay Packers image thumbnail GB Thu, Sep 24 • 8:15 PM ET
Rushing Yards
MarShawn Lloyd logo MarShawn Lloyd o26.5 Rushing Yards (-115)
Best Odds
Pick made: an hour ago
Neil Parker logo
Neil Parker
Betting Analyst

This is a low number for Lloyd, and I’d recommend him to Over 29.5 for Thursday Night Football. He closed with a 45.5 rushing yards total in Week 2 and at 50.5 in the season opener, after all. Additionally, while Lloyd has been held to just 3.0 yards per carry and 2.11 yards after contact per attempt, he’s handled a healthy 48.7% of the Green Bay rushes and did post a high-end 87.5 PFF elusive rating in Week 1.

Receiving Yards
Bijan Robinson logo Bijan Robinson o39.5 Receiving Yards (-115)
Best Odds
Pick made: an hour ago
Joe Osborne logo
Joe Osborne
Senior Betting Analyst

Bijan topped this number comfortably in Week 1 with eight catches for 90 yards before a Week 2 blowout shortened his workload. He averaged 53.7 receiving yards on 6.2 targets in Penix’s starts last season, clearing 39.5 in five of nine games. Against Green Bay’s stout run defense, Atlanta could lean on short passes to get its best weapon involved.

View 17 Picks
Kansas City Chiefs image thumbnail KC @ Miami Dolphins image thumbnail MIA Sun, Sep 27 • 1:00 PM ET
Anytime Touchdown
De'Von Achane logo
De'Von Achane Score a Touchdown (Yes: -105)
Projection 0.68 (Yes)
Best Odds
Pick made: 2 minutes ago
EV Model Rating
Star rating: 4 out of 5
At a -11.5-point disadvantage, the Dolphins are heavy underdogs in this game, implying much more of an emphasis on moving the ball through the air than their standard game plan.. De'Von Achane has been a big part of his team's pass game near the goal line, posting a Red Zone Target Share of 18.0% since the start of last season, which places him in the 96th percentile among RBs.. When talking about air yards, De'Von Achane grades out in the towering 96th percentile among RBs since the start of last season, totaling a massive 4.0 per game. (because they are often targeted behind the line of scrimmage, that is far more remarkable than it sounds since most RBs have negative air yards).. De'Von Achane ranks in the 99th percentile when it comes to running back WOPR (Weighted Opportunity Rating—an advanced metric that weighs high-value offensive volume) with a superb 32.3 figure since the start of last season.. De'Von Achane ranks in the 92nd percentile among running backs as it relates to catching TDs since the start of last season, averaging a fantastic 0.20 per game.
Anytime Touchdown
Rashee Rice logo
Rashee Rice Score a Touchdown (Yes: +190)
Projection 0.52 (Yes)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 4 out of 5
At the present time, the 10th-most pass-focused team in the league in the red zone (57.8% in a neutral context) according to the projections is the Chiefs.. The 8th-highest number of plays in the league have been called by the Kansas City Chiefs since the start of last season (a massive 59.1 per game on average).. With a high 15.4% Red Zone Target% (78th percentile) this year, Rashee Rice ranks as one of the wide receivers with the highest volume near the end zone in the NFL.. Rashee Rice ranks in the 77th percentile among wide receiver WOPR (Weighted Opportunity Rating—an advanced metric that quantifies high-value offensive usage) with a colossal 49.4 mark since the start of last season.. The Kansas City Chiefs offensive line ranks as the 9th-best in the league since the start of last season in protecting the quarterback, which has a strong influence on all passing attack metrics across the board.
View 3 Picks
Carolina Panthers image thumbnail CAR @ Cleveland Browns image thumbnail CLE Sun, Sep 27 • 1:00 PM ET
Rushing Yards
Quinshon Judkins logo Quinshon Judkins o43.5 Rushing Yards (-115)
Best Odds
Pick made: an hour ago
Neil Parker logo
Neil Parker
Betting Analyst

This Judkins Over is in play to 46.5 because Carolina has allowed the highest yards per carry (6.31) to opposing running backs while ranking 29th in run defense DVOA through two weeks. The Cleveland rusher also cleared this total in nine of 14 games last season, and he has handled 75% of running back carries with a 66% snap share to start 2026. Judkins’ go-to role positions him to scamper well Over this number in the soft Week 3 matchup.

Total
Carolina Panthers image thumbnail Cleveland Browns image thumbnail o41.0 (-110)
Best Odds
Pick made: yesterday
Jason Logan logo
Jason Logan
Senior Betting Analyst

The Cleveland Browns finished No. 6 in EPA per dropback in Week 2. Deshaun Watson had his best game in a long time despite the Bucs bringing the heat, picking up 7.0 yards per pass. Carolina has thrown on 64% of dropbacks after a shootout with Chicago and a squash of Atlanta to kick off 2026. Quarterback Bryce Young is thriving with offensive coordinator Brad Idzik calling plays. He’s Top 10 in all the fancy passing stats, including air yards. Both teams have given up plays over the top, sitting sixth and seventh in most air yards allowed. The Panthers defense looks tougher than it truly is after fattening up on the Falcons’ backup QBs in Week 2. Carolina still got gashed for 157 rushing yards from Atlanta, despite focusing their energy on stuffing the run.

View 5 Picks
Tennessee Titans image thumbnail TEN @ New York Giants image thumbnail NYG Sun, Sep 27 • 1:00 PM ET
Spread
New York Giants image thumbnail NYG -5.5 (-115)
Best Odds
Pick made: yesterday
Neil Parker logo
Neil Parker
Betting Analyst

Grabbing this -5.5 line before Monday Night Football because I’m expecting the Giants to hang with the Los Angeles Rams in Week 2, and New York will be an even larger home favorite over Tennessee by Sunday afternoon. The Titans were only on offense for 23:35 against the Philadelphia Eagles on Sunday, and QB Cam Ward has thrown for just 6.2 yards per attempt through two weeks. Tennessee also hits the highway for the first time in 2026, and the new-look G-Men put on an offensive clinic in their season opener at MetLife Stadium. 

Anytime Touchdown
Jaxson Dart logo
Jaxson Dart Score a Touchdown (Yes: +175)
Projection 0.48 (Yes)
Best Odds
Pick made: 36 minutes ago
EV Model Rating
Star rating: 4 out of 5
Since the start of last season, the weak Tennessee Titans defense has allowed a staggering 75.0% Adjusted Completion Rate to opposing quarterbacks: the 2nd-worst rate in the NFL.
View 2 Picks
New England Patriots image thumbnail NE @ Jacksonville Jaguars image thumbnail JAC Sun, Sep 27 • 1:00 PM ET
Spread
Jacksonville Jaguars image thumbnail JAC -2.5 (-110)
Best Odds
Pick made: yesterday
Jason Logan logo
Jason Logan
Senior Betting Analyst

I won’t discount the Jaguars too much for having a tough day in Denver. Jacksonville gets to come home for what will be its only outing in Duval County until Week 8. The Patriots looked much better than they were against the corpse of Aaron Rodgers in Week 2. New England managed just 20 points – seven coming from a defensive score – went 4-for-12 on third down and 0 for 1 in the red zone. This Jaguars defense still did a lot right against the Broncos, standing tall on third downs and inside the red zone. I’ll take the home side short of the key number of three.

Anytime Touchdown
Romeo Doubs logo
Romeo Doubs Score a Touchdown (Yes: +305)
Projection 0.39 (Yes)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 5 out of 5
At a -3-point disadvantage, the Patriots are underdogs in this week's game, suggesting more of an emphasis on throwing than their typical approach.. The projections expect the New England Patriots to be the most pass-heavy offense in the league near the end zone (context-neutralized) at the moment with a 76.2% red zone pass rate.. Opposing quarterbacks have averaged 36.4 pass attempts per game vs. the Jaguars defense since the start of last season: 2nd-most in the league.. Romeo Doubs has been a key part of his team's pass game near the goal line, earning a Red Zone Target Share of 22.4% since the start of last season, which puts him in the 92nd percentile among wideouts.. As it relates to air yards, Romeo Doubs ranks in the lofty 81st percentile among wide receivers since the start of last season, accruing a superb 69.0 per game.
View 4 Picks
Los Angeles Chargers image thumbnail LAC @ Buffalo Bills image thumbnail BUF Sun, Sep 27 • 1:00 PM ET
Rushing Yards
Omarion Hampton logo
Omarion Hampton o58.5 Rushing Yards (-114)
Projection 70.92 (Over)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 5 out of 5
At the moment, the 5th-most run-heavy offense in the NFL (41.2% adjusted for context) according to the model is the Chargers.. The 4th-largest volume of plays in the NFL have been called by the Los Angeles Chargers since the start of last season (a monstrous 59.4 per game on average).. The Chargers have played in the 10th-most "low wind" (4-mph or less) games in football since the start of last season, which ought to lead to lower pass volume, increased running volume, and reduced passing attack efficiency when facing windier conditions this week.. Opposing offenses have run for the 10th-most adjusted yards in football (127 per game) against the Buffalo Bills defense since the start of last season.. The Buffalo Bills defensive ends rank as the 2nd-worst group of DEs in the NFL since the start of last season in regard to run defense.
Passing Attempts
Justin Herbert logo
Justin Herbert u31.5 Passing Attempts (-105)
Projection 29.51 (Under)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 4 out of 5
The model projects the Chargers to be the 5th-least pass-heavy offense in the NFL (adjusted for context) at the present time with a 58.8% pass rate.. The leading projections forecast the Chargers to call the 8th-fewest offensive plays on the slate this week with 62.3 plays, based on their underlying play style and game dynamics.. The Chargers have played in the 10th-most "low wind" (4-mph or less) games in football since the start of last season, which ought to lead to lower pass volume, increased running volume, and reduced passing attack efficiency when facing windier conditions this week.. In this week's game, Justin Herbert is forecasted by the model to average the 8th-fewest pass attempts among all QBs with 31.8. . Opposing quarterbacks have averaged 29.4 pass attempts per game against the Bills defense since the start of last season: 5th-fewest in the league.
View 10 Picks
New York Jets image thumbnail NYJ @ Detroit Lions image thumbnail DET Sun, Sep 27 • 1:00 PM ET
Total
New York Jets image thumbnail Detroit Lions image thumbnail u48.5 (-120)
Best Odds
Pick made: 21 hours ago
Ed Scimia logo
Ed Scimia
Betting Analyst

The New York Jets have allowed just 4.0 yards per play, third-best in the NFL, and rank sixth in EPA per defensive play for the season. And while the Detroit Lions have given up an embarrassing 457.5 yards per game on defense, Geno Smith and the New York offense haven't shown any signs that they can even approach that kind of number. I'm backing the Under at totals as low as 47.5 points.

Spread
Detroit Lions image thumbnail DET -6.5 (-116)
Best Odds
Pick made: 21 hours ago
Ed Scimia logo
Ed Scimia
Betting Analyst

The New York Jets defense still looks legit, but the offense sputtered against its first real taste of adversity, totaling just 285 yards against the Green Bay Packers. That won't be enough to deal with a Detroit Lions team that has averaged 362 yards and 31.0 ppg on offense this season. I'm backing the Lions to cover at -6.5 points.

View 12 Picks
Houston Texans image thumbnail HOU @ Indianapolis Colts image thumbnail IND Sun, Sep 27 • 1:00 PM ET
Total
Houston Texans image thumbnail Indianapolis Colts image thumbnail o43.5 (-116)
Best Odds
Pick made: yesterday
Dustin Saracini logo
Dustin Saracini
Senior Analyst

We have two teams that have hit the Over in three of four games this year, leading me to believe that this number is far too low. The Colts' defense is simply the worst in football so far, giving up a total of eight touchdowns through two weeks. Most of these are due to a struggling red-zone unit, which is coughing up a score 67% of the time. So what's been working for Indy? Undeniably, its offense, which is scoring at an 84% clip once they get inside the 20. While yes, the Colts are going up against one of the better defensive units in football, Houston has still allowed over 350 yards of total offense in the early parts of 2026. What does this all add up to? An Over. Play this up to 55%.

Spread
Houston Texans image thumbnail HOU -2.5 (-137)
Best Odds
Pick made: yesterday
Dustin Saracini logo
Dustin Saracini
Senior Analyst

The Houston Texans defense has faced two of the most potent offenses in football, the Buffalo Bills and Cincinnati Bengals, and still comes out on top in virtually every statistical category against the Indianapolis Colts. The Colts have a major issue, allowing 514 total yards per game - the most in the NFL by almost 60 yards. That coincides with allowing 37 points per game, also the worst mark in the league. They'll be going up against an offense that ranks in the top 10 in yards per game, which is good enough for me to get behind the Texans, even if Nico Collins misses another game. I'm expecting David Montgomery to run all over Indy, which is allowing 5.4 yards per carry through two weeks of the season. Comfortably fade the Colts and play this up to 60%.

View 2 Picks
Seattle Seahawks image thumbnail SEA @ Washington Commanders image thumbnail WAS Sun, Sep 27 • 1:00 PM ET
Anytime Touchdown
Jadarian Price logo
Jadarian Price Score a Touchdown (Yes: +120)
Projection 0.57 (Yes)
Best Odds
Pick made: 2 minutes ago
EV Model Rating
Star rating: 4 out of 5
The Seahawks will be forced to start backup quarterback Drew Lock in this game, which generally means fewer pass attempts and more rushes.. The Washington Commanders defense has given up the 9th-most receiving touchdowns in football to RBs: 0.21 per game since the start of last season.. The Commanders safeties project as the 4th-worst safety corps in the league since the start of last season in defending pass-catchers.
View Pick
Cincinnati Bengals image thumbnail CIN @ Pittsburgh Steelers image thumbnail PIT Sun, Sep 27 • 1:00 PM ET
Moneyline
Cincinnati Bengals image thumbnail CIN (-174)
Best Odds
Pick made: yesterday
Jason Logan logo
Jason Logan
Senior Betting Analyst

Pittsburgh takes a series step up in competition and this is no longer the Steelers we could count on under Mike Tomlin. Aaron Rodgers is done and Cincinnati is looking like the best two-way team in the NFL, after handling Houston on the road in Week 3. The Bengals have collected eight sacks in the first two games and I wouldn’t be surprised if Rodgers doesn’t make it through Week 3, given the pounding he took in New England.  Oh, and Joe Burrow is absolutely firing on all cylinders. He’s surgical versus zone coverage and will slice up Patrick Graham’s passive playcalling. I'm taking Cincy ML before this price ticks up to two bucks or higher.

Anytime Touchdown
Ja'Marr Chase logo
Ja'Marr Chase Score a Touchdown (Yes: +160)
Projection 0.51 (Yes)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 4 out of 5
The predictive model expects the Cincinnati Bengals to be the most pass-focused offense on the slate this week with a 64.7% pass rate, given their underlying play style and matchup dynamics.. The predictive model expects the Cincinnati Bengals to be the 2nd-most pass-oriented team in the NFL near the goal line (context-neutralized) at the present time with a 62.0% red zone pass rate.. The model projects the Cincinnati Bengals to be the 8th-fastest paced defense in football (context-neutralized) at the moment, leading opposing offenses to average 28.13 seconds per snap.. The Steelers defense has been a glaring pass funnel since the start of last season, leading opposing quarterbacks to attempt the 5th-most passes in the NFL (34.3 per game) since the start of last season.. Ja'Marr Chase has been an integral part of his team's passing offense near the goal line, garnering a Red Zone Target Share of 26.4% since the start of last season, which places him in the 95th percentile among WRs.
View 3 Picks
Arizona Cardinals image thumbnail ARI @ San Francisco 49ers image thumbnail SF Sun, Sep 27 • 4:05 PM ET
Anytime Touchdown
Christian McCaffrey logo
Christian McCaffrey Score a Touchdown (Yes: -210)
Projection 0.91 (Yes)
Best Odds
Pick made: 2 minutes ago
EV Model Rating
Star rating: 4 out of 5
At the moment, the 10th-most pass-focused team in the league near the goal line (60.3% in a neutral context) according to the predictive model is the 49ers.. While Christian McCaffrey has garnered 75.2% of his offense's red zone carries in games he has played since the start of last season, the leading projections forecast him to be a much smaller piece of San Francisco's running game near the goal line this week at 61.5%.. Christian McCaffrey has accrued a colossal 19.0 air yards per game since the start of last season: 100th percentile among RBs. (This may not seem too impressive, but most RBs average negative air yards due to most of their targets being behind the line of scrimmage).. Christian McCaffrey's 40.5 WOPR (Weighted Opportunity Rating—an advanced statistic that examines high-value offensive usage) puts him in the company of the best in football: 100th percentile for running backs.. With an excellent rate of 0.32 per game through the air (100th percentile), Christian McCaffrey places among the best receiving TD-scorers in the NFL when it comes to RBs since the start of last season.
Anytime Touchdown
Trey McBride logo
Trey McBride Score a Touchdown (Yes: +280)
Projection 0.48 (Yes)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 5 out of 5
An extreme passing game script is suggested by the Cardinals being an enormous -8.5-point underdog in this week's game.. The model projects the Arizona Cardinals as the 3rd-most pass-focused team on the slate this week with a 62.5% pass rate, given their underlying propensities and matchup dynamics.. The Cardinals have run the 7th-most plays in the NFL since the start of last season, totaling a monstrous 59.2 plays per game.. With a top-tier 34.5% Red Zone Target Rate (99th percentile) since the start of last season, Trey McBride stands as one of the tight ends with the biggest workloads near the goal line in the league.. When it comes to air yards, Trey McBride grades out in the lofty 100th percentile among tight ends since the start of last season, accumulating a remarkable 67.0 per game.
View 3 Picks
Minnesota Vikings image thumbnail MIN @ Tampa Bay Buccaneers image thumbnail TB Sun, Sep 27 • 4:05 PM ET
Total
Minnesota Vikings image thumbnail Tampa Bay Buccaneers image thumbnail u42.5 (-108)
Best Odds
Pick made: yesterday
Dustin Saracini logo
Dustin Saracini
Senior Analyst

We're seeing two mediocre offenses against two top-10 defenses in Week 3. The Vikings have had to play mistake-free football on both sides of the ball - their defense has allowed an average of just 12.5 points per game as a result. It's also one of the best red-zone defenses this year, allowing a touchdown on just 12% of trips inside the 20. With positive regression looming for the Bucs' defense against Murray and Co. I'm projecting this total to close closer to 40.5.

Spread
Tampa Bay Buccaneers image thumbnail TB +1.5 (-111)
Best Odds
Pick made: yesterday
Dustin Saracini logo
Dustin Saracini
Senior Analyst

The Tampa Bay Buccaneers are better than their 0-2 record indicates, and it's put-up-or-shut-up time against the Minnesota Vikings in Week 3 if they want to win a weak NFC South. It's probably a welcome sight that Kyler Murray will likely get the start, with Carson Wentz leading the Vikings to two wins in his absence. Murray played just 11 snaps in the team's opener before leaving with a concussion, and now draws a difficult matchup against a top-10 defense. Baker Mayfield hasn't gotten going this year yet (albeit, he was playing in rain in Week 2), but the offense has too much talent surrounding him to lay low for one more week. I'm expecting a bigger breakout in what should finally be a sunny day in Tampa.

View 3 Picks
Baltimore Ravens image thumbnail BAL @ Dallas Cowboys image thumbnail DAL Sun, Sep 27 • 4:25 PM ET
Total
Baltimore Ravens image thumbnail Dallas Cowboys image thumbnail o52.5 (-105)
Best Odds
Pick made: yesterday
Neil Parker logo
Neil Parker
Betting Analyst

Baltimore just allowed New Orleans Saints QB Tyler Shough to throw for 7.4 yards per attempt with a 79.4 completion percentage in Week 2, and now the Ravens go up against a Dallas offense that’s fourth in both EPA per play and offensive success rate ahead of Monday Night Football in Week 2. Of course, there’s no stop on defense for the Cowboys, and the Ravens respectively check in sixth and third in the two highlighted metrics. Finally, I anticipate the trip south to Maracana Stadium to also take its toll on the two defenses in Week 3.

Receiving Yards
Javonte Williams logo
Javonte Williams u17.5 Receiving Yards (-114)
Projection 13.97 (Under)
Best Odds
Pick made: 2 minutes ago
EV Model Rating
Star rating: 5 out of 5
As far as a defense's effect on pace, the Cowboys defense has caused opposing squads to play 8th-slowest in football (in a neutral context) since the start of last season at 30.14 seconds per snap.. When it comes to air yards, Javonte Williams ranks in the paltry 6th percentile among running backs since the start of last season, totaling just -4.0 per game.. The Dallas Cowboys offensive line grades out as the 3rd-worst in the league since the start of last season in protecting the QB, which has a negative effect on all pass game statistics across the board.
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Las Vegas Raiders image thumbnail LV @ New Orleans Saints image thumbnail NO Sun, Sep 27 • 4:25 PM ET
Anytime Touchdown
Michael Mayer logo
Michael Mayer Score a Touchdown (Yes: +700)
Projection 0.29 (Yes)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 5 out of 5
A passing game script is indicated by the Raiders being a -3-point underdog in this game.. Accounting for their underlying play style and matchup dynamics, the projections expect the Raiders to pass on 60.2% of their chances: the 9th-greatest clip among all teams this week.. The predictive model expects this game to see the highest number of plays run out of all the games this week at 133.5 plays, accounting for the play styles of each team and game dynamics.. This game will be played in a dome—which means no wind, increased pass volume, increased touchdown potential, and better passing effectiveness.. While Michael Mayer has garnered 13.7% of his offense's red zone targets in games he has played since the start of last season, our trusted projections expect him to be a more integral piece of Las Vegas's passing offense near the goal line this week at 23.1%.
Anytime Touchdown
Tyler Shough logo
Tyler Shough Score a Touchdown (Yes: +340)
Projection 0.34 (Yes)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 4 out of 5
Our trusted projections expect the New Orleans Saints to be the 10th-most pass-centric offense in the league near the end zone (context-neutralized) right now with a 57.8% red zone pass rate.. The projections expect this game to have the highest number of plays run among all games this week at 132.7 plays, based on the traits of each team and game dynamics.. The New Orleans Saints have called the 3rd-most plays in the league since the start of last season, totaling a staggering 60.4 plays per game.. The passing attacks of both teams (including both volume and efficiency) ought to benefit from the calm "weather" conditions (i.e. zero wind) inside this dome, while ground volume may suffer.. The Raiders linebackers grade out as the 3rd-worst unit in the NFL since the start of last season in pass coverage.
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Los Angeles Rams image thumbnail LA @ Denver Broncos image thumbnail DEN Sun, Sep 27 • 8:20 PM ET
Anytime Touchdown
Jaylen Waddle logo
Jaylen Waddle Score a Touchdown (Yes: +190)
Projection 0.42 (Yes)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 4 out of 5
The projections expect the Denver Broncos to be the 10th-most pass-centric offense on the slate this week with a 59.8% pass rate, given their underlying traits and matchup dynamics.. Right now, the 5th-most pass-oriented team in the league near the end zone (61.0% adjusted for context) according to our trusted projection set is the Broncos.. Based on their underlying play style and game dynamics, the Broncos are expected by our trusted projection set to run 65.3 plays on offense in this contest: the 8th-most on the slate this week.. The Denver Broncos have called the 9th-most plays in the NFL since the start of last season, averaging a colossal 58.4 plays per game.. The Los Angeles Rams defense has been a glaring pass funnel since the start of last season, causing opposing quarterbacks to attempt the 6th-most passes in the league (34.1 per game) since the start of last season.
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Philadelphia Eagles image thumbnail PHI @ Chicago Bears image thumbnail CHI Mon, Sep 28 • 8:15 PM ET
Anytime Touchdown
Jalen Hurts logo
Jalen Hurts Score a Touchdown (Yes: +170)
Projection 0.53 (Yes)
Best Odds
Pick made: 26 minutes ago
EV Model Rating
Star rating: 4 out of 5
The Eagles have played in the most "bad weather" (rain, snow, or 15+ mph wind) games in the league since the start of last season, which ought to result in increased pass volume, reduced running volume, and improved passing offense performance when facing better weather in this game.. When talking about pass-blocking (and the positive effect it has on all pass attack stats), the O-line of the Eagles profiles as the 2nd-best in the NFL since the start of last season.. Jalen Hurts has been one of the leading TD throwers in the NFL since the start of last season, averaging a terrific 1.58 per game while grading out in the 85th percentile.. Opposing teams have completed passes at the 5th-highest clip in the league vs. the Bears defense since the start of last season (74.0% Adjusted Completion%).. The Chicago Bears defense has yielded the 5th-most TDs through the air in the league: 1.84 per game since the start of last season.
Receiving Yards
Colston Loveland logo
Colston Loveland o25.5 Receiving Yards (-115)
Projection 41.22 (Over)
Best Odds
Pick made: 28 minutes ago
EV Model Rating
Star rating: 5 out of 5
This week's spread indicates a throwing game script for the Bears, who are -3-point underdogs.. Our trusted projections expect this game to see the 3rd-highest number of plays run among all games this week at 131.0 plays, accounting for the approaches of each team and game dynamics.. The Chicago Bears have run the 2nd-most plays in football since the start of last season, totaling a colossal 61.1 plays per game.. The Chicago O-line ranks as the 6th-best in the league since the start of last season in protecting the passer, which has a positive influence on all passing game stats across the board.. The Eagles safeties grade out as the 5th-worst safety corps in the NFL since the start of last season in defending pass-catchers.
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For every matchup in an NFL season, our NFL computer produces selections for a variety of different betting angles. Our computer picks are based on a proprietary algorithm that values each team in the current week to produce moneyline, spread, and point total selections.

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You can use our NFL computer as a jumping-off point to do more research into specific lines, cross-referencing with expert picks, which can be found above the selections for some matchups, recent NFL betting trends, and more.

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There is a correlation between moneyline odds and the spread, as books set these lines based on the same information.

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