PIT -2.5 o38.5
CLE 2.5 u38.5
IND -3.5 o47.0
WAS 3.5 u47.0
ARI -1.5 o44.0
NYG 1.5 u44.0
NE 6.5 o48.5
BUF -6.5 u48.5
NYJ 3.5 o43.0
CHI -3.5 u43.0
DAL 2.5 o48.0
HOU -2.5 u48.0
LA -3.5 o44.5
PHI 3.5 u44.5
GB -3.5 o39.5
TB 3.5 u39.5
TEN 11.5 o43.5
BAL -11.5 u43.5
JAC 2.5 o51.0
CIN -2.5 u51.0
MIA 10.5 o38.5
MIN -10.5 u38.5
KC -4.5 o47.5
LV 4.5 u47.5
LAC 7.5 o43.0
SEA -7.5 u43.0
DEN 2.5 o47.0
SF -2.5 u47.0
DET -3.5 o50.5
CAR 3.5 u50.5
ATL 2.5 o48.0
NO -2.5 u48.0
Denver 3rd AFC West2-1
San Francisco 1st NFC West3-0

Broncos vs 49ers   Picks & Props

DEN vs SF Picks

NFL Picks
Total
Denver Broncos image thumbnail San Francisco 49ers image thumbnail o46.5 (-108)
Best Odds
Pick made: 18 hours ago
Dustin Saracini logo
Dustin Saracini
Senior Analyst

Even against a strong Denver defense, the 49ers have the explosiveness to create scoring opportunities. It helps that they own the best red-zone offense in football - scoring 90% of their trips inside the 20. Denver shouldn't need a huge offensive performance to get this game over the number, either. Nix showed flashes on Sunday Night Football in his 16-0 comeback victory, and is in a groove after two straight wins. 

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San Francisco 49ers image thumbnail SF -2.5 (-116)
Best Odds
Pick made: 18 hours ago
Dustin Saracini logo
Dustin Saracini
Senior Analyst

The San Francisco 49ers have been remarkably efficient on offense, with Brock Purdy leading a unit that generates an NFL-best 7.35 yards per play while also ranking first with 0.32 EPA per play. While injuries are beginning to pile up, the 49ers received encouraging news regarding Mike Evans on Monday. His presence will provide a significant boost against a stingy Denver Broncos defense. My biggest concern remains Bo Nix, who won't have the luxury of overcoming another slow start against this San Francisco team. The 49ers also boast a top-five red-zone defense, giving me plenty of confidence in their ability to cover.

DEN vs SF Consensus Picks

More Consensus

Consensus Picks

Our consensus picks show you what percentage of the public is betting on, you'll need to decide whether you want to bet with or against the public.

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69% picking San Francisco

31%
69%

Total Picks DEN 134, SF 303

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SF
Total

49% picking Denver vs San Francisco to go Under

51%
49%

Total PicksDEN 126, SF 121

Total
Over
Under

DEN vs SF Props

GAME & PLAYER PROPS PROJECTIONS ANALYSIS BEST ODDS
SPREAD
Denver Broncos image thumbnail
DEN +2.5 spread
1.30 PROJECTION
-1.2 DIFFERENCE
12.58% EV
Rating: Star rating: 4 out of 5
Best odds Caesars
Best Odds
Denver Broncos image thumbnail
DEN +2.5 spread

PROJECTION

1.30 PROJECTION
-1.2 DIFFERENCE
12.58% EV

ANALYSIS

There is no analysis available at the moment. Please check back later.

+3.5 -132
Caesars logo
TOTAL
Denver Broncos image thumbnail San Francisco 49ers image thumbnail
Over 46.5 Total
48.28 OVER PROJECTION
+1.8 DIFFERENCE
11.9% EV
Rating: Star rating: 3 out of 5
Best odds Caesars
Best Odds
Denver Broncos image thumbnail San Francisco 49ers image thumbnail
Over 46.5 Total

PROJECTION

48.28 OVER PROJECTION
+1.8 DIFFERENCE
11.9% EV

ANALYSIS

There is no analysis available at the moment. Please check back later.

o46.5 -108
Caesars logo
  • Proj. Diff: Low to High
  • Proj. Diff: High to Low
  • Proj. Rating: Low to High
  • Proj. Rating: High to Low
  • +EV: Low to High
  • +EV: High to Low
SPREAD
Denver Broncos image thumbnail
DEN +2.5 spread
1.30 PROJECTION
-1.2 DIFFERENCE
12.58% EV
Rating: Star rating: 4 out of 5
Best odds Caesars
Best Odds
Denver Broncos image thumbnail
DEN +2.5 spread

PROJECTION

1.30 PROJECTION
-1.2 DIFFERENCE
12.58% EV

ANALYSIS

There is no analysis available at the moment. Please check back later.

+3.5 -132
Caesars logo
TOTAL
Denver Broncos image thumbnail San Francisco 49ers image thumbnail
Over 46.5 Total
48.28 OVER PROJECTION
+1.8 DIFFERENCE
11.9% EV
Rating: Star rating: 3 out of 5
Best odds Caesars
Best Odds
Denver Broncos image thumbnail San Francisco 49ers image thumbnail
Over 46.5 Total

PROJECTION

48.28 OVER PROJECTION
+1.8 DIFFERENCE
11.9% EV

ANALYSIS

There is no analysis available at the moment. Please check back later.

o46.5 -108
Caesars logo

DEN vs SF Top User Picks

More Picks

User Picks

Our user picks are made by you, our valued users - we highlight the best user picks, sharing the users who are on a hot streak.

Total

'Kazual12' picks Denver vs San Francisco to go Under (46.5)

Kazual12 is #1 on picking games that San Francisco is in with a record of (3-0-0) and +3000 units on the season.

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Under
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'gator49' is picking San Francisco to cover (-2.5)

gator49 is #10 on picking games that Denver is in with a record of (1-0-0) and +2000 units on the season.

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SF
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'BIGGEDD17' is picking San Francisco to cover (-3.0)

BIGGEDD17 is #5 on picking games that San Francisco is in with a record of (3-0-0) and +3000 units on the season.

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'BIGGEDD17' picks Denver vs San Francisco to go Under (45.5)

BIGGEDD17 is #5 on picking games that San Francisco is in with a record of (3-0-0) and +3000 units on the season.

Total
Over
Under
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'rquiroz' is picking San Francisco to cover (-2.5)

rquiroz is #7 on picking games that San Francisco is in with a record of (1-0-0) and +2000 units on the season.

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