Thursday Night Football odds for Week 3 feature an AFC East matchup between the Miami Dolphins and Buffalo Bills.
The look-ahead line opened with the Bills as double-digit favorites, following a horrific opening week effort from Miami.
Thursday Night Football odds
Dolphins vs Bills live odds
Dolphins vs Bills opening odds
- Point spread: Dolphins +10.0 | Bills -10.0
- Moneyline: Dolphins +375 | Bills -500
- Total: Over 48.5 | Under 48.5
Thursday Night Football 2025 schedule & results
| Date | Matchup | Time |
|---|---|---|
| 9/4 Week 1 |
Cowboys (20) at Eagles (24) | 8:20 NBC |
| 9/11 Week 2 |
Commanders (18) at Packers (27) | 8:15 PRIME |
| 9/18 Week 3 |
Dolphins at Bills | 8:15 PRIME |
| 9/25 Week 4 |
Seahawks at Cardinals | 8:15 PRIME |
| 10/2 Week 5 |
49ers at Rams | 8:15 PRIME |
| 10/9 Week 6 |
Eagles at Giants | 8:15 PRIME |
| 10/16 Week 7 |
Steelers at Bengals | 8:15 PRIME |
| 10/23 Week 8 |
Vikings at Chargers | 8:15 PRIME |
| 10/30 Week 9 |
Ravens at Dolphins | 8:15 PRIME |
| 11/6 Week 10 |
Raiders at Broncos | 8:15 PRIME |
| 11/13 Week 11 |
Jets at Patriots | 8:15 PRIME |
| 11/20 Week 12 |
Bills at Texans | 8:15 PRIME |
| 11/27 Week 13 |
Packers at Lions | 12:30 FOX |
| 11/27 Week 13 |
Chiefs at Cowboys | 4:30 CBS |
| 11/27 Week 13 |
Bengals at Ravens | 8:20 NBC |
| 12/4 Week 14 |
Cowboys at Lions | 8:15 PRIME |
| 12/11 Week 15 |
Falcons at Buccaneers | 8:15 PRIME |
| 12/18 Week 16 |
Rams at Seahawks | 8:15 PRIME |
| 12/25 Week 17 |
Cowboys at Commanders | 1:00 NETFLIX |
| 12/25 Week 17 |
Lions at Vikings | 4:30 NETFLIX |
| 12/25 Week 17 |
Broncos at Chiefs | 8:15 PRIME |
| No TNF matchup in Week 18 |
TNF betting tips
From Jason Logan, Covers Senior Industry Analyst
What happened before?
Thursday games present a tight turnaround for the teams involved. Look back at the teams’ recent schedule challenges and see if this short week compounds a busy calendar — especially for the road team. Practice and prep time are at a premium during these short weeks... and they will lose a day to travel.
Injuries loom large
Thursday games also leave less time for teams to heal up. Injured players don’t have the same window for recovery and are often ruled out early. Even players nursing bumps and bruises, or playing through pain, can feel the squeeze of the short week, so read up on who’s hurting — but not listed on the injury report.
Coaching matters
Coaching can give a big edge on the short week. Give the benefit of the doubt to veteran coaches and experienced staff, who are known for their game prep and have navigated the challenges of TNF before.
Baby, it (gets) cold outside
Thursday night games can also be an advantage for cold weather teams come December and January. Temperatures plummet when the sun goes down and places like Green Bay, Chicago, and Buffalo turn into frozen wastelands. While the sub-zero temps impact both sides, visitors from warmer cities or indoor stadiums may struggle to adapt when the mercury drops.
Home-field frenzy
Home-field advantage can get a bit of a boost on Thursday nights. The home crowd has been tailgating all day, rather than partying for a 1 p.m. or 4 p.m. ET kickoff. That ravenous crowd is then released into the stadium, giving the home hospitality a little extra bite.
Thursday Night Football Odds FAQ
There is one TNF game each week, mostly broadcast on Amazon Prime, with the exception tripleheaders on Thanksgiving and Christmas Day.
The Dallas Cowboys play four games on Thursday this season, while the Detroit Lions play thrice on TNF.
The Indianapolis Colts entered 2025 with the most TNF wins ever, with 12 victories in 16 games played.
The Kansas City Chiefs entered 2025 as the winningest team since TNF began in 2006, with a .786 win percentage (11-3).
