A couple of rising stars at the quarterback position will lead their teams into Thursday Night Football action, with Jordan Love and the Green Bay Packers playing host to Jayden Daniels and the Washington Commanders.
Both squads got off to great starts in Week 1 with Green Bay dominating the Lions 27-13 and Washington easily defeating the Giants 21-6.
Green Bay's favored by 3.5, but my Commanders vs. Packers predictions and NFL picks expect one of Washington's new stars to have a big impact on the game and fill up the stat sheet on Thursday, September 11.
Commanders vs Packers prediction
Commanders vs Packers Best bet: Deebo Samuel Over 4.5 receptions (-118)
Make no mistake about it, a healthy Deebo Samuel is still one of the top weapons in the NFL.
This was on full display last week as he was a major factor in both the passing and running games for the Washington Commanders in their beatdown of the Giants.
While his touchdown came on his lone carry – a 19-yard run in the fourth quarter – he was Jayden Daniels’ favorite target. Deebo was on the receiving end of 10 targets, leading to seven receptions and 77 yards.
While Daniels spread the ball around with eight separate players receiving a target, the 10 in Samuel's direction were five more than any of his teammates.
It's clear that Kliff Kingsbury plans to use Samuel to his full extent and will take creative measures to get him involved in the offense, as seen on the reverse sweep handoff that led to his TD.
The Green Bay Packers defense was strong in Week 1 against Detroit, but it did allow Jared Goff to complete 31 passes on 39 attempts.
Commanders vs Packers TNF same-game parlay
With lots of potential touches in both the passing and running games, don’t be shocked to see Deebo in the end zone. Meanwhile, this game sets up nicely for Josh Jacobs against a Commanders defense that allowed the second-most rushing yards per game last season.
Commanders vs Packers SGP
- Samuel Over 4.5 receptions
- Jacobs Over 77.5 rushing yards
- Samuel anytime TD
Our big-ticket SGP: Double the fun for Josh Jacobs
With a big day potentially on the way for Jacobs, let’s take him to get into the end zone twice. He had three multi-TD games last season.
Commanders vs Packers SGP
- Jacobs 2+ TDs
- Samuel anytime TD
- Jacobs Over 77.5 rushing yards
- Samuel Over 4.5 receptions
Commanders vs Packers odds
- Spread: Washington +3.5 | Green Bay -3.5
- Moneyline: Washington +155 | Green Bay -185
- Over/Under: Over 48 | Under 48
Commanders vs Packers betting trend to know
The Washington Commanders have hit the Moneyline in 7 of their last 11 away games (+8.75 Units / 52% ROI)
Find more NFL betting trends for Commanders vs. Packers.
How to watch Commanders vs Packers
Location | Lambeau Field, Green Bay, WI |
Date | Thursday, September 11, 2025 |
Kickoff | 8:15 p.m. ET |
TV | Amazon Prime |
Commanders vs Packers latest injuries
Commanders vs Packers weather
Monitor gametime conditions with our live NFL weather info and learn how weather impacts NFL betting.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.