The Cleveland Browns and Tennessee Titans are both coming off a win as they meet in Nashville. It's the Titans' first of the season, while it puts the Browns in first place.
My Browns vs. Titans prediction and NFL picks call for a low-scoring affair, with the Browns covering.
The game kicks off at 1 p.m. ET Sunday from Nashville's Nissan Stadium. The Browns will be the road favorite on CBS.
TOP Pick
Browns vs Titans prediction: Browns -1.5
The spread is low, and the Browns have the same straight-up and ATS results in the first six weeks, so giving up the points shouldn’t be a problem. I’d stick with Browns giving points until 53% or jump to the moneyline if it drops to 53%.
Cleveland has been getting it done on defense. Cleveland has been getting it done on defense. The Browns rank seventh in scoring defense, allowing 20.3 points per game, and have surrendered just one rushing touchdown through six games.
The Browns haven't been strong against the run, but Tennessee ranks 27th in rushing, averaging just 82.8 yards per game. They’re also in the bottom three in scoring, total yards, first downs, and EPA per play.
Cleveland has been scoring just enough to win, and there’s no reason to doubt that trend will continue in Tennessee.

Browns vs Titans combo
The total has dropped by a point as the week has gone on.
The numbers still indicate this should go Under. Both teams have been Under in three of the last four weeks, and neither team has scored more than 27 points yet this year.
They’ve also allowed that many points only once. The Browns hope RBs Quinshon Judkins (ankle) and Dylan Sampson (IR knee) will both be back for the game after practicing this week.
Cleveland sack leader Mason Graham (knee, ankle) could also return. The boost to the Browns’ run game and pass rush should help control the clock and keep the Titans off the board.
Browns vs Titans combo
- Browns -1.5 (51%)
- Under 36.5 (48%)
- Titans 1H Under 8.5 points
Browns vs Titans touchdown scorer: Denzel Boston
The rookie leads the AFC in yards per catch and has finished half of Cleveland’s games in the end zone this year.
Denzel Boston will be matched against a Titans secondary that ranks 27th in the league in PFF grading. Tennessee has also forced the fewest turnovers in the NFL, and its pass rush gives opposing quarterbacks the third-most time in the pocket in the league.
That should create a perfect storm to allow Deshaun Watson to find Boston for at least one deep ball.
- Top picks: 14-10, +19.62 units
- Combos: 1-4, +1.0 units
Browns vs Titans odds
For help understanding probabilities, see our odds calculator.
- Spread: Browns -1.5 (51%) | Titans +1.5 (50%)
- Over/Under: Over 36.5 (53%) | Under 36.5 (48%)
- Moneyline: Browns 55% | Titans 46%
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Browns vs Titans trend to know
The Tennessee Titans have only hit the 1H Moneyline in 4 of their last 19 games (-11.30 Units / -50% ROI). Find more NFL betting trends for Browns vs. Titans.
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How to watch Browns vs Titans
| Location | Nissan Stadium, Nashville, Tennessee |
| Date | Sunday, Oct. 25, 2026 |
| Kickoff | 1:00 p.m. ET |
| TV | CBS |
Browns vs Titans latest injuries
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Odds are correct at the time of publishing and are subject to change.
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