The NFL International Series continues in Week 7 with the Pittsburgh Steelers growing favorites over the New Orleans Saints ahead of their 9:30 a.m. ET kickoff at Stade de France in Saint-Denis, France on Sunday, Oct. 25.
My favorite Steelers vs. Saints prediction and NFL picks call for the Black and Gold running game and defense to have their say in covering the number across the pond.
TOP Pick
Steelers vs Saints prediction: Steelers -2.5
The New Orleans Saints can’t stop the run and rank 32nd in rush defense DVOA while allowing the highest rushing success rate.
It’s been a huge contributor to the Saints tying for the second-most points against per game (29.7), and it’s a particularly poor shortcoming against the Pittsburgh Steelers in this Week 7 showdown.
The Steelers rank second in rushing DVOA and fifth in EPA per rush, so I’m happy to back the Black and Gold below the key number of 4.
Pittsburgh is set to control the time of possession, and its defense is also far more formidable, with ranks of eighth in DVOA while allowing the sixth-lowest EPA per play.

Steelers vs Saints combo
Pittsburgh welcomed Rico Dowdle back in Week 6, and he rushed for a healthy 5.7 yards per carry, including 3.14 yards after contact per attempt and a 37.5% breakaway percentage.
He’ll approach — if not reach — double-digit rushes Sunday, and in addition to the highlighted New Orleans shortcomings against the run, the Saints have allowed six different backs to pick up 30 or more rushing yards through five games.
Turning to New Orleans veteran Alvin Kamara, he’s plodded for 15 or more rushing yards in five of six games, and his prior lowest total in this market was 22.5 in Week 1.
Steelers vs Saints combo
- Steelers moneyline
- Rico Dowdle 30+ rushing yards
- Alvin Kamara 15+ rushing yards
Steelers vs Saints touchdown scorer: Jaylen Warren
With the Saints allowing 12 touchdowns to opposing running backs through six games, I would recommend Steelers running back Jaylen Warren to find the end zone up to 60%.
He's posted top-five ranks in yards per carry (6.5), yards after contact per attempt (3.94) and PFF elusive rating (98.5) across the past four weeks, and Warren is also a threat through the air with a league-high 14.1 yards per reception among backs during the run.
- Top picks: 35-30, +3.78 units
- Combos: 0-12, -12.0 units
Steelers vs Saints odds
For help understanding probabilities, see our odds calculator.
- Spread: Steelers -3.5 | Saints +3.5
- Over/Under: Over 44.5 (50%) | Under 44.5 (51%)
- Moneyline: Steelers 63% | Saints 38%
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Steelers vs Saints weather
The forecast calls for partially cloudy skies with a game-time temperature of 59°F and a moderate 17.5 mph west wind blowing from sideline to sideline that could bring light rain showers (26% P.O.P.).
Check out our NFL weather page for up-to-date info on every matchup.
Steelers vs Saints trend to know
The Pittsburgh Steelers have covered the spread in 12 of their last 21 games (+2.25 Units / 10% ROI). Find more NFL betting trends for Steelers vs. Saints.
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How to watch Steelers vs Saints
| Location | Stade de France, Saint-Denis, France |
| Date | Sunday, Oct. 25, 2026 |
| Kickoff | 9:30 a.m. ET |
| TV | NFL Network |
Steelers vs Saints latest injuries
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Odds are correct at the time of publishing and are subject to change.
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