NFL Week 11 odds open for action with an AFC South clash on Thursday Night Football as the Houston Texans host the Indianapolis Colts as home favorites.
Sunday’s slate builds toward a primetime showdown on Sunday Night Football, where the Minnesota Vikings head west to take on the San Francisco 49ers at Levi's Stadium.
NFL Week 11 wraps up on Monday Night Football with an inter-conference battle as the Washington Commanders host the Cincinnati Bengals.
Here’s a look at the Week 11 NFL odds, spreads, totals, and moneylines—and where those markets are moving.
NFL odds Week 11
| Matchup | Spread | Moneyline | Over/Under |
|---|---|---|---|
 Coltsvs  Texans |
OTB | 20% 80% |
OTB |
 Dolphinsvs  Bills |
OTB | 9% 92% |
OTB |
 Saintsvs  Bears |
OTB | 19% 83% |
OTB |
 Titansvs  Cowboys |
OTB | 19% 81% |
OTB |
 Buccaneersvs  Lions |
OTB | 39% 63% |
OTB |
 Cardinalsvs  Chiefs |
OTB | 11% 90% |
OTB |
 Steelersvs  Eagles |
OTB | 68% 36% |
OTB |
 Ravensvs  Panthers |
OTB | 49% 54% |
OTB |
 Jetsvs  Chargers |
OTB | 47% 52% |
OTB |
 Raidersvs  Broncos |
OTB | 22% 80% |
OTB |
 Jaguarsvs  Giants |
OTB | 71% 31% |
OTB |
 Vikingsvs  49ers |
OTB | 36% 65% |
OTB |
 Bengalsvs  Commanders |
OTB | 67% 36% |
OTB |
Lines as of 11-11.
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Thursday Night Football: Colts vs Texans odds (8:15 p.m. ET, Prime)
Opening line
- Texans — Coming soon!
- Over/Under — Coming soon!
- View full Colts vs. Texans odds and matchup
- Read our Colts vs. Texans picks and predictions (coming soon)
Opening line analysis coming soon!
Also see: full Thursday Night Football odds
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Sunday Night Football: Vikings vs 49ers odds (8:20 P.M. ET, NBC)
Opening line
- 49ers — Coming soon!
- Over/Under — Coming soon!
- View full Vikings vs. 49ers odds and matchup
- Read our Vikings vs. 49ers picks and predictions (coming soon)
Opening line analysis coming soon!
Also see: full Sunday Night Football odds
Monday Night Football: Bengals vs Commanders odds (8:15 p.m. ET, ESPN)
Opening line
- Commanders — Coming soon!
- Over/Under — Coming soon!
- View full Bengals vs. Commanders odds and matchup
- Read our Bengals vs. Commanders picks and predictions (coming soon)
Opening line analysis coming soon!
Also see: full Monday Night Football odds
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Odds are correct at the time of publishing and are subject to change.
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