Opening NFL Week 13 Odds and Betting Lines: Ride 'Em Underdog Cowboys

We've got a full slate of games in NFL Week 13, starting with a Thanksgiving Day triple-header and a special Black Friday battle.

The Green Bay Packers and Detroit Lions (-3) get things started on Thursday afternoon before giving way to the Kansas City Chiefs, who are clinging to life, at the Dallas Cowboys (+3.5).

Thursday Night Football features an AFC North rivalry bout between the Cincinnati Bengals and Baltimore Ravens. Could Joe Burrow be active?

The Chicago Bears will yet again have a chance to outplay expectations, but it'll come with the steep task of topping the Philadelphia Eagles (-7) at the Linc.

Here are the NFL odds for Week 13 and early line moves.

NFL odds Week 13

Matchup	Spread	Moneyline	Over/Under
Packers vs Lions	Lions -2.5	Packers +124 Lions -146	49.5
Chiefs vs Cowboys	Cowboys +3	Chiefs -180 Cowboys  +152	51.5
Bengals vs Ravens	Ravens -7	Bengals +270 Ravens -335	51.5
Bears vs Eagles	Eagles -7	Bears +270 Eagles -3335	44.5
Jaguars vs Titans	Titans +6.5	Jaguars -330 Titans +265	41.5
Falcons vs Jets	Jets +2.5	Falcons -146 Jets +124	39.5
Rams vs Panthers	Panthers +10.5	Rams -750 Panthers +530	45.5
Saints vs Dolphins	Dolphins -5.5	Saints +235 Dolphins -290	42.5
Cardinals vs Buccaneers	Buccaneers -3	Cardinals +134 Buccaneers -158	44.5
49ers vs Browns	Browns +6.5	49ers -290 Browns +235	39.5
Texans vs Colts	Colts -4.5	Texans +180 Colts -215	44.5
Vikings vs Seahawks	Seahawks -10.5	Vikings +480 Seahawks -650	41.5
Bills vs Steelers	Steelers +3.5	Bills -210 Steelers +176	47.5
Raiders vs Chargers	Chargers -9.5	Raiders +430 Chargers -590	41.5
Broncos vs Commanders	Commanders +6.5	Broncos -340 Commanders +275	43.5
Giants vs Patriots	Patriots -7.5	Giants +340 Patriots -430	46.5

Lines as of 11-25

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Packers vs Lions odds (Thursday, 1:00 p.m. ET, FOX)

Opening line

• Lions -3
• Over/Under 49.5
• View full Packers vs. Lions odds and matchup
• Read our Packers vs. Lions picks and predictions (coming soon)

This NFC North battle opened with Detroit as a field goal favorite for its annual Thanksgiving home game, with the line slightly padded toward the Packers.

The vig has started to balance out in the opening 12 hours of action. The health of Green Bay RB Josh Jacobs will influence this spread before Thursday. The total hit the board at 49.5 points after the look-ahead line sat at 48.5 O/U before the results of Week 12.

Also see: full Thursday Night Football odds

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Chiefs vs Cowboys odds (Thursday, 4:30 p.m. ET, CBS)

Opening line

• Cowboys +3.5
• Over/Under 52.5
• View full Chiefs vs. Cowboys odds and matchup
• Read our Chiefs vs. Cowboys picks and predictions (coming soon)

The Cowboys are coming off a wild comeback win over the Eagles in Week 12 and have a short turnaround to brace for the Chiefs, who completed a comeback of their own with a win over the Colts on Sunday. Dallas was a 4-point home pup on the look-ahead line but after Week 12, this spread opened Cowboys +3.5 (-115). The total hit the board at 52.5 points and has since slimmed to 51.5 O/U.

Also see: full Thursday Night Football odds

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Bengals vs Ravens odds (Thursday, 8:20 p.m. ET, NBC)

Opening line

• Ravens -7.5
• Over/Under 52.5
• View full Bengals vs. Ravens odds and matchup
• Read our Bengals vs. Ravens picks and predictions (coming soon)

All eyes are on Bengals QB Joe Burrow, who was back at practice in Week 12 and is expected to return to action for this Thanksgiving run-in with the Ravens. Books opened Cincinnati as a 7.5-point road underdog after the look-ahead line was as big as +11.5 last week. The total has also been adjusted, with the look-ahead number at 49.5 and jumping to an official opener of 52.5 before coming down to 51.5 points.

Also see: full Thursday Night Football odds

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Bears vs Eagles odds (Friday, 3:00 p.m. ET, Prime Video)

Opening line

• Eagles -7
• Over/Under 42.5
• View full Bears vs. Eagles odds and matchup
• Read our Bears vs. Eagles picks and predictions (coming soon)

Black Friday sees a standalone game between the Bears and Eagles at 3 p.m. ET. Philadelphia blew a 21-0 lead in Dallas on Sunday and opened as a touchdown favorite after that collapse. The total opened 42.5 and has jumped to 43.5 with early action on the Over.

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Jaguars vs Titans odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

• Titans +7
• Over/Under 42.5
• View full Jaguars vs. Titans odds and matchup
• Read our Jaguars vs. Titans picks and predictions (coming soon)

Jacksonville stays on the road for a second straight week and watched its opening spread of -7 dip to -6.5 against the Titans in Week 13. Tennessee has shown some fight in back-to-back games, most recently putting a scare in Seattle on Sunday. This Over/Under opened at 42.5 and has dropped to 41.5 O/U in the first 12 hours of action.

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Falcons vs Jets odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Jets +2.5
• Over/Under 39.5
• View full Falcons vs. Jets odds and matchup
• Read our Falcons vs. Jets picks and predictions (coming soon)

The Falcons picked up a win at New Orleans despite missing QB1 Michael Penix Jr. and star WR Drake London. Atlanta opened as a 2.5-point favorite at New York in Week 13 while the total hit the board at 39.5 points. The Jets offense looked livelier with Tyrod Taylor under center on Sunday.  

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Rams vs Panthers odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Panthers +10.5
• Over/Under 45.5
• View full Rams vs. Panthers odds and matchup
• Read our Rams vs. Panthers picks and predictions (coming soon)

Look-ahead lines were Rams -9.5 but after Los Angeles’ one-sided win on SNF and the Panthers loss to San Francisco on MNF, the official opener came out at L.A. -10.5. The total hit the board at 45.5 points.

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Saints vs Dolphins odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Dolphins -5.5
• Over/Under 42.5
• View full Saints vs. Dolphins odds and matchup
• Read our Saints vs. Dolphins picks and predictions (coming soon)

Miami is coming off the bye and opened as a 5.5-point home chalk to New Orleans, which could be without RB Alvin Kamara in Week 13. Some books have already moved to Dolphins -6. The Over/Under opened at 42.5 points. 

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Cardinals vs Buccaneers odds (Sunday, 1:00 p.m. ET, FOX)

Opening line

• Buccaneers -5.5
• Over/Under 48.5
• View full Cardinals vs. Buccaneers odds and matchup
• Read our Cardinals vs. Buccaneers picks and predictions (coming soon)

Tampa Bay could be without starting QB Baker Mayfield after he injured his shoulder in Sunday night’s loss in Los Angeles. The opening odds reflect that loss under center, with the Bucs going from 5.5-point home favorites versus Arizona to -2.5.

The total also moved, officially opening at 45.5 after a look-ahead number of 48.5 prior to Sunday’s events. Cardinals WR Marvin Harrison Jr. is still questionable after recovery from an appendectomy.

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49ers vs Browns odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

• Browns +6.5
• Over/Under 40.5
• View full 49ers vs. Browns odds and matchup
• Read our 49ers vs. Browns picks and predictions (coming soon)

San Francisco picked up a win over Carolina on Monday and opened as a 6.5-point road chalk at Cleveland in Week 13, but the spread is padded toward Browns +6.5 with many other books down to six points. The total opened at 40.5 and dropped to 39.5 with early action on the Under. Snow, rain and 30 mph gust are in the forecast for Cleveland on Sunday. 

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Texans vs Colts odds (Sunday, 1:00 p.m. ET, CBS)

Opening line

• Colts -3.5
• Over/Under 46.5
• View full Texans vs. Colts odds and matchup
• Read our Texans vs. Colts picks and predictions (coming soon)

Indianapolis has to recover from a collapse at Kansas City in time for this important AFC South showdown with Houston. The Texans are coming off a mini bye after beating Buffalo last Thursday and could have QB C.J. Stroud back from a concussion. The Colts opened as 3.5-point home favorites while the total opened at 46.5 and has since slimmed to 44.5 points.

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Vikings vs Seahawks odds (Sunday, 4:05 p.m. ET, FOX)

Opening line

• Seahawks -7
• Over/Under 43.5
• View full Vikings vs. Seahawks odds and matchup
• Read our Vikings vs. Seahawks picks and predictions (coming soon)

The Vikings travel for the second straight week, heading to Seattle in Week 13. The Seahawks opened as 8.5-point favorites and have climbed to -9.5 with early play on the home side. This total hit the board at 43.5 points and slimmed to 42.5 O/U.

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Bills vs Steelers odds (Sunday, 4:25 p.m. ET, CBS)

Opening line

• Steelers +3.5
• Over/Under 47.5
• View full Bills vs. Steelers odds and matchup
• Read our Bills vs. Steelers picks and predictions (coming soon)

Buffalo has had to wait a while to bounce back from a loss last Thursday and travels to Pittsburgh as a 4.5-point road favorite in Week 13. The Steelers are unsure of their starting QB situation with Aaron Rodgers nursing a fractured left wrist, which held him out of Week 12. This total opened at 47.5 points.

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Raiders vs Chargers odds (Sunday, 4:25 p.m. ET, CBS)

Opening line

• Chargers -9.5
• Over/Under 42.5
• View full Raiders vs. Chargers odds and matchup
• Read our Raiders vs. Chargers picks and predictions (coming soon)

Las Vegas fired offensive coordinator Chip Kelly in the wake of an ugly home loss to Cleveland in Week 12 and opened as a 9.5-point road underdog against the Chargers, who are coming off a much-needed bye week. This total hit the board at 42.5 and is now down to 41.5 O/U.

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Broncos vs Commanders odds (Sunday, 8:20 p.m. ET, NBC)

Opening line

• Commanders +6.5
• Over/Under 43.5
• View full Broncos vs. Commanders odds and matchup
• Read our Broncos vs. Commanders picks and predictions (coming soon)

Both the Broncos and Commanders were off in Week 12. Washington opened as a 6.5-point home underdog with the status of QB Jayden Daniels up in the air. The Commanders are also hoping to get stud WR Terry McLaurin back in action against Denver. This Over/Under number opened at 43.5 points.

Also see: full Sunday Night Football odds

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Giants vs Patriots odds (Monday, 8:15 p.m. ET, ESPN)

Opening line

• Patriots -7.5
• Over/Under 47.5
• View full Giants vs. Patriots odds and matchup
• Read our Giants vs. Patriots picks and predictions (coming soon)

The Giants almost scored a huge upset over Detroit in Week 12 and now travel to New England as 7.5-point road underdogs. The Patriots continued their winning ways with a tough victory over Cincinnati, and could be down two starters on the offensive line for this Monday Night Football matchup. The total hit the board at 47.5 and has bounced between 48.5 and 46.5 in the first 12 hours of action.

Also see: full Monday Night Football odds

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