The New England Patriots will look to keep the good times rolling when they welcome the struggling New York Giants to town on Monday Night Football.
Our Giants vs. Patriots predictions are full of NFL picks for you to wager on as Week 13 comes to a close on December 1.
Giants vs Patriots MNF predictions
- Patriots -7 (-110 at bet365)
- Under 46.5 (-110 at bet365)
- Henderson anytime TD (-115 at bet365)
- Tracy Jr. Over 2.5 receptions (-115 at bet365)
Giants vs Patriots MNF best bets
Patriots -7
Even with Jaxson Dart returning for New York, Josh Inglis expects the Pats to get it done.
"I know the New York Giants are exciting, but the injuries on defense and the reduction of Dart's scrambling are a lot for a team that was already struggling to be competitive. This is also a defense that has folded late week in and week out."
Under 46.5
Inglis isn't too confident in Dart & Co. putting up enough points to eclipse this total.
"The weather shouldn't impact anything, but the health of Dart worries me about how conservative this New York offense will be. I think I'd like this Over 46.5 more if Jameis was still slinging it."
Giants vs Patriots MNF TD picks
TreVeyon Henderson
Trevor Knapp is expecting big things from the Pats' rookie RB on Monday Night Football.
"TreVeyon Henderson has established himself as the lead back for the New England Patriots. Henderson currently sports a team-leading six touchdowns on the season, with five of them coming over his last three games. He’s also been targeted nine times through the air during that stretch, and I expect him to keep the production rolling at home."
Giants vs Patriots MNF props
Tyrone Tracy Jr. Over 2.5 receptions
Jason Logan believes Tyrone Tracy Jr. will be kept busy in the passing game against New England.
"Ever since Mike Kafka (now interim head coach) took over play calling, Tyrone Tracy has emerged as a potent piece of the New York passing game. He’s drawn three or more targets in four of his last five games and in seven of his 10 games overall. And since fellow RB Cam Skattebo went down, Tracy has caught at least three balls in three of his last four outings (at least an 11% target share in three of those four) — including seven catches for 119 total receiving yards the last two weeks."
Giants vs Patriots odds
Giants vs Patriots game info
| Location: | Gillette Stadium, Foxborough, MA |
| Date: | Monday, December 1, 2025 |
| Kickoff: | 8:15 p.m. ET |
| TV: | ESPN |
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Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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