The New England Patriots enter Monday Night Football as 7-point home favorites, riding a nine-game winning streak and surging behind steady offense and strong first-half play.
The Giants, meanwhile, limp in on a six-game losing skid and now turn back to Jaxson Dart, who returns from a concussion after missing the last two games.
With New England rolling and New York struggling to generate consistency, my Giants vs. Patriots predictions and NFL picks believe this December 1 matchup sets up as another uphill climb for the Giants in Foxborough.
Giants vs Patriots prediction
Giants vs Patriots Best bet: Patriots -4 1H (-110)
Jaxson Dart has been cleared from concussion protocol and will start Monday night after missing two games in which Jameis Winston helped the offense score 47 total points against Detroit and Green Bay. Most of that production came early, and with Dart returning, this offense could start slower than usual.
Dart had been dangerous on the ground, averaging 45 rushing yards per game over his last seven games, but it’s fair to expect less reckless scrambling given the recent injury. He’ll also be working with a supporting cast full of backups outside of tight end.
The New England Patriots are coming off what feels like a “bad game,” yet they still scored 26 points on Cincinnati, won the first half by four, and Drake Maye threw for 294 yards.
Their issues were in the red zone (0-for-2), but OC Josh McDaniels addressed those problems this week and hinted at more creativity near the goal line. This is also the No. 5 1H scoring offense in the league.
New England should also benefit from injuries on the New York Giants’ defense. Dexter Lawrence is more doubtful than probable, and both starting linebackers — Demetrius Flannigan-Harris and Kayvon Thibodeaux — missed Friday’s practice.
Losing any combination of those three offsets New England’s own O-line injuries, especially given the Patriots still rank Top 5 in most protection metrics.
Dart likely needs time to settle in, New York’s offensive explosiveness should dip, and the Patriots should finish drives against the league’s 31st-ranked red-zone defense.
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Giants vs Patriots MNF same-game parlay
Hunter Henry remains Drake Maye’s most reliable target and is coming off a season-high 115 yards with his fifth touchdown, tying him for the team lead. Four of his five scores have come at home, where he also averages 10 more receiving yards per game.
TreyVon Henderson should continue to handle most of the backfield work after Rhamondre Stevenson managed just five yards on six carries and failed at the goal line last week in his return. With McDaniels acknowledging last week’s red-zone issues, Henderson could see increased close-range usage.
Theo Johnson is another overlooked option. He’s coming off a season-high 77 yards and was a clear Jaxson Dart favorite earlier in the year, scoring five touchdowns in the seven games Dart started.
Giants vs Patriots 3-leg SGP
- Hunter Henry TD
- Treveyon Henderson TD
- Theo Johnson TD
Our big-ticket SGP: Handoffs & hook routes TD parlay
I'm adding the New York back that took over the goal-line last week. Tyrone Tracy had five carries inside the 20 compared to Devin Singletary's one, which went for a loss of four yards. You'd also have to assume that Jaxson Dart isn't poaching close TDs this week with his concussion issues.
Giants vs Patriots 4-leg SGP
- Hunter Henry TD
- Treveyon Henderson TD
- Theo Johnson TD
- Tyrone Tracy TD
Giants vs Patriots odds
- Spread: Giants +7 | Patriots -7
- Moneyline: Giants +275 | Patriots -350
- Over/Under: Over 46.5 | Under 46.5
Giants vs Patriots betting trend to know
The Patriots are 8-3-1 ATS in the first half this season. Find more NFL betting trends for Giants vs. Patriots.
How to watch Giants vs Patriots
| Location | Gillette Stadium, Foxborough, MA |
| Date | Monday, December 1, 2025 |
| Kickoff | 8:15 p.m. ET |
| TV | ESPN |
Giants vs Patriots latest injuries
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