Buccaneers vs Seahawks Predictions, Picks & Best Bets for NFL Week 5

Our expert NFL predictions expect the Seahawks to continue their winning ways when they host the Buccaneers in Week 5.

Sam Farley - Contributor at Covers.com
Sam Farley • Betting Analyst
Oct 4, 2025 • 12:34 ET • 4 min read

NFL

Match starts: 19 hrs
SEA
48 %
TB
52 %
EXPERT PICK - SPREAD
Seattle -3.5 (-110) Seattle -3.5 (-110)
Read Analysis
Kenneth Walker of the Seattle Seahawks
Photo By - Imagn Images. Kenneth Walker of the Seattle Seahawks.

On Sunday, we have the Tampa Bay Buccaneers and Seattle Seahawks meeting in Seattle. 

Both teams are 3-1, with the Seahawks riding a wave of victories, while the Bucs will look to bounce back after their first defeat of the season.

The Seahawks have started the season very well, and our picks are backing them to continue by covering the spread.

Don’t miss our Buccaneers vs. Seahawks predictions and NFL picks for October 5. 

Buccaneers vs Seahawks prediction

Buccaneers vs Seahawks Best bet: Seahawks -3.5 (-110)

Both teams sit at 3-1, and both have serious playoff aspirations. There are also question marks around the teams that have played. 

The Seattle Seahawks lost their season opener but have followed that up with three straight wins. However, a closer look shows that victories came against the Steelers (3-1), Saints (0-4), and Cardinals (2-2). 

Meanwhile, the Tampa Bay Buccaneers have beaten the Jets, Falcons, and Texans and lost to the Eagles last week, meaning that they have yet to beat a team without a winning record. Baker Mayfield has shown some clutch moments late in games, but the Bucs can’t keep relying on him to pull off magic at the end of games.

We also need to remember that Baker Mayfield will be without Mike Evans and Bucky Irving, and that could be crucial, given the Bucs' 0-4 record in games without Evans since 2023. 

The Seahawks have also been quietly going under the radar and surprisingly rank number one for defensive DVOA and sixth overall for offensive DVOA. The Seahawks aren’t glamorous, but they’re well coached and doing the basics well.

In Sam Darnold they have a QB who ranks inside the top 10 in competition percentage, QB rating, and yards per pass attempt.

This Seahawks team has allowed the second-fewest points per game, and with the injuries mounting for the Buccaneers, we’ll take the home team to cover the spread.

Buccaneers vs Seahawks same-game parlay

In addition to our best bet, we’re going to back Sean Tucker to have Under 27.5 rushing yards. The running back has had just one carry this season, and it came in the opening week, but with Bucky Irving injured, he’s expecting his role to grow. 

For the final leg, we’re backing Kenneth Walker to score. Walker led the backfield in Week 4, and that should happen again on Sunday. 

Buccaneers vs Seahawks SGP

  • Seattle Seahawks -3.5
  • Sean Tucker Under 27.5 rushing yards
  • Kenneth Walker anytime touchdown

Our big-ticket SGP: Kupp Runneth Over!

Our lottery same-game parlay is going big by adding two legs to our above SGP. For the first one, we’re backing the Bucs’ Cade Otton to score. The tight end hasn’t found the end zone yet, but this game gives him a great opportunity with Evans being ruled out. 

No team has allowed more tight end receptions than the Seahawks, so we could see Otton get his first score of the season and big odds.

We’re also backing Cooper Kupp to have Over 3.5 receptions. It’s a number that he’s hit in two of four games this season, and most crucially last week. He‘s averaging five targets per game and should get plenty of targets in a game that looks like it could be fairly close.

Buccaneers vs Seahawks SGP

  • Seattle Seahawks -3.5
  • Sean Tucker Under 27.5 rushing yards
  • Kenneth Walker anytime touchdown
  • Cade Otton anytime touchdown
  • Cooper Kupp Over 3.5 receptions

Buccaneers vs Seahawks odds

  • Spread: Buccaneers +2.5 (-110) | Seahawks -2.5 (-110)
  • Moneyline: Buccaneers +115 | Seahawks -135
  • Over/Under: Over 44.5 (-115) | Under 44.5 (-105)

More NFL picks and odds from Covers


Buccaneers vs Seahawks trend to know

Seattle is 3-0-0 ATS across their last three games. Find more NFL betting trends for Buccaneers vs. Seahawks.

How to watch Buccaneers vs Seahawks

Location Lumen Field, Seattle, WA
Date Sunday, October 5, 2025
Kickoff 4:05 p.m. ET
TV CBS

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Sam Farley
Betting Analyst

Sam is based in the United Kingdom, where he grew up living and breathing soccer, before discovering - and playing - a different kind of football at the University of Bristol. He’s worked in the media covering soccer and the NFL for the better part of a decade, and has been a regular on the Matchbook NFL Podcast. His work has also appeared in a wide range of publications including The Telegraph, The Independent, VICE, and MSN.

The search for great betting value is a daily one, and Sam always hunts out big prices with a particular focus on player props. Sam’s best advice for bettors is to track their bets on a spreadsheet, that way you can keep an eye on your P&L but also the types of bets and sports that you are most successful in. He also recommends using a variety of different sportsbooks, with bet365, Betfair and Paddy Power amongst his favorites.

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