The Arizona State vs. Kansas prediction and college football picks favors the Sun Devils as 5.5-point favorites in Saturday’s Union Jack Classic at Wembley Stadium.
Arizona State’s offensive efficiency gives it the edge over a Kansas team coming off a disappointing loss to Missouri, and I’m backing the favorite to push the game over the total while scoring at least four touchdowns.
Here is our Week 3 view on the matchup.
TOP PICK
Who will win Arizona State vs Kansas: Arizona State -5.5 (51%)
With Arizona State favored by only 5.5 points, I’m comfortable laying the number to 55%.
ASU outgained Texas A&M 369-255 last week, but four turnovers turned a competitive performance into a 48-20 loss. The Kansas Jayhawks have a less convincing underlying profile, ranking 56th nationally in 2025 adjusted EPA per play at +0.10 and 84th in raw EPA per play at -0.07.
The Jayhawks also managed only 248 total yards against Missouri after dominating an inferior opponent in Week 1. Arizona State’s offense has shown more reliable explosiveness.
The Sun Devils are the better team and deserves to be favored in London.

Arizona State vs Kansas Over/Under pick: Over 51.5 (49%)
The efficiency numbers point to more scoring potential than Kansas’ recent loss suggests and I'm playing the Over up to 55% because of that.
Kansas posted a +0.10 adjusted EPA per play last season, ranking 56th nationally, while Arizona State has shown enough offensive explosiveness to move the ball against quality competition as previously mentioned.
Both teams have quarterbacks capable of creating explosive plays, while Arizona State’s turnover issues add volatility rather than making me want to fade the offense entirely. A 31-24 type of game gets this over the number.
Arizona State vs Kansas combo
Arizona State should be able to establish control early against a Kansas team coming off a poor offensive performance against Missouri.
The Sun Devils’ offensive efficiency gives them a path to build a lead, while the full-game over leaves room for Kansas to contribute enough scoring to keep the game active.
If Arizona State plays to its status as the favorite, this combination can cash without requiring a blowout.
Arizona State vs Kansas combo
- Arizona State 1H moneyline
- Over 51.5
- Arizona State -5.5
- Top picks: 1-1, -0.10 units
- Combos: 1-1, +3.9 units
Arizona State vs Kansas odds
For help understanding probabilities, see our odds calculator.
- Spread: Arizona State +5.5 | Kansas -5.5
- Over/Under: Over 50.5 (48%) | Under 50.5 (52%)
- Moneyline: Arizona State 34% | Kansas 64%
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Arizona State vs Kansas weather
Cloudy with no rain, while a brisk 14 mph wind could have minor impacts to the passing game.
Check out our college football weather page for up-to-date info on every matchup.
Arizona State vs Kansas trend to know
Sun Devils are 5-0 ATS in their last 5 neutral site games.
How to watch Arizona State vs Kansas
| Location | Wembley Stadium, London, England |
| Date | Saturday, Sept. 19, 2026 |
| Kickoff | 12 p.m. ET |
| TV | FS1 |
Arizona State vs Kansas latest injuries
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Odds are correct at the time of publishing and are subject to change.
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