The Buffalo Sabres head to TD Garden with another chance to close out their series against the Boston Bruins in Game 6 tonight.
My top Sabres vs. Bruins predictions and NHL picks are backing Buffalo to punch its ticket to Round 2 on Friday, May 1.
Puck drop is set for 7:30 p.m. ET in Boston, with the game airing on TNT and Sportsnet 360.
- UPDATE: Added a prediction for who will win tonight.
Sabres vs Bruins Game 6 prediction
Who will win Sabres vs Bruins Game 6?
Buffalo Sabres: This is a letdown spot for the Bruins after leaving it all on the line to eke out the Game 5 win on the road.
Buffalo won both of the first two games in Boston, and the Sabres have won the possession and expected goals battle at five-on-five, so I fully expect the series to end in Game 6.
Sabres vs Bruins best bet: Sabres moneyline (-115)
Jeremy Swayman stole Game 5 for the Boston Bruins with seven high-danger saves and 2.80 goals saved above expected, and I fully expect a dip from Swayman to allow the Buffalo Sabres to capitalize on enough chances to win Game 6.
Swayman’s scattered just 0.71 GSAx across the other four games of the series, after all.
Buffalo has also dominated the time of possession at 5-on-5 with a 55.6 Corsi For percentage, and the Sabres held the Bruins to just 11 goals and 15.56 expected goals through five games, including only 2.75 xGF at TD Garden.
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Sabres vs Bruins Game 6 same-game parlay
Don’t let some of the high scores in this series fool you. Boston has only scored once in the first period through five games, and four of Buffalo’s five first-period goals came in Game 4. With another elimination game on tap, expect to see attention to defensive detail to be on full display.
Turning to the final leg of this same-game parlay, Alex Tuch has been a force for the Sabres. He found the scoresheet in each of the first four games of the series and has been on the ice for an impressive 8.89 expected goals.
Sabres vs Bruins SGP
- Sabres moneyline
- Under 1.5 first-period goals
- Alex Tuch Over 0.5 points
Sabres vs Bruins Game 6 goal scorer pick
Jason Zucker (+320)
Buffalo winger Jason Zucker is up to 2.48 individual expected goals and 10 high-danger scoring chances without finding the back of the net in Round 1.
The eight-time, 20-goal scorer continues to generate quality scoring opportunities, and he’s receiving consistent top-six minutes at 5-on-5 while also jumping the boards with the No. 1 power-play unit, so he's in the right role to break through in Game 6.
Sabres vs Bruins odds for Game 6
- Moneyline: Sabres -115 | Bruins -105
- Puck Line: Sabres -1.5 (+215) | Bruins +1.5 (-265)
- Over/Under: Over 5.5 (-120) | Under 5.5 (+100)
Sabres vs Bruins trend
The Buffalo Sabres have won 19 of their last 25 away games (+14.25 Units / 50% ROI). Find more NHL betting trends for Sabres vs. Bruins.
How to watch Sabres vs Bruins Game 6
| Location | TD Garden, Boston, MA |
| Date | Friday, May 1, 2026 |
| Puck drop | 7:30 p.m. ET |
| TV | ESPN, Sportsnet 360 |
Sabres vs Bruins latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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