The Los Angeles Chargers and Los Angeles Rams share a stadium and will share the field on Sunday. The Rams have had the better start to the season and will be the "home" team
However, my Chargers vs. Rams prediction and NFL picks are for the Chargers to get their first cover and threaten their first win.
TOP Pick
Chargers vs Rams prediction: Chargers +6.5
We’re going with the underdog, and we’ll stick with the Chargers and the points until 54% and a long look at the moneyline below 30%.
The Chargers still have all the offensive skill-position talent that made them a popular pick to contend for the AFC West title heading into the season. The problem has been giving them time to work.
The Chargers had four rookies on the offensive line in their last game. They had last week off to get healthy, while offensive coordinator Mike McDaniel tinkered with schemes and explored new protection options.
Joe Alt should be back on the line. He wasn’t even listed on the injury report. The Chargers also hoped to get back guard Kayode Awosika, but he hasn’t practiced this week. Receiver Ladd McConkey (concussion) has also been a full participant and should be back.

Chargers vs Rams combo
Traditionally, Justin Herbert has been successful when under pressure. This game should test how often the Rams can get to him.
The Rams posted a 66.7% pass-rush win rate against the Giants earlier this season, their highest single-game mark since 2022.
However, when quarterbacks get the pass off, the defense pays the price for selling out, as the Rams have allowed the NFL's highest yards-after-catch average. Look for Herbert to hit enough big gains to keep it close, even if he takes hits.
Overall, the Rams have allowed 30+ points twice and 20+ points twice in their last five games. The Chargers defense has allowed 22+ in every game, so there should be plenty of points on the board.
Chargers vs Rams combo
- Chargers +6.5
- Over 45.5
- Chargers Over 17.5 points
Chargers vs Rams touchdown scorer: Kimani Vidal
McDaniel is an offensive wizard who has been under pressure during the Chargers’ 0-6 start. Given a bye week to tinker, he’ll come up with an unexpected twist, and that could involve Kimani Vidal.
The running back has seen his time increase in recent weeks at the expense of Omarion Hampton, who has played less than 50% of the offensive snaps over the last four games. Vidal had the same number of touches as Hampton last game.
If the Rams get their pressure to Herbert, the quarterback will be looking to dump off to an RB, and Vidal has more targets than Hampton and a slightly higher average yards after catch per reception, an area where the Rams D has struggled.
- Top picks: 14-11, +18.62 units
- Combos: 1-5, +0.0 units
Chargers vs Rams odds
For help understanding probabilities, see our odds calculator.
- Spread: Chargers +6.5 (51%) | Rams -6.5 (50%)
- Over/Under: Over 45.5 (50%) | Under 45.5 (51%)
- Moneyline: Chargers 27% | Rams 73%
For the full slate of NFL matchups, check out our NFL odds board!
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Chargers vs Rams weather
SoFi Stadium has a roof but is open on the sides, so temperature outside will matter. The L.A. weather Sunday won't be a factor, roof or no. Sunny and high 60s for most of the game.
Check out our NFL weather page for up-to-date info on every matchup.
Chargers vs Rams trend to know
The Over is 4-0 in the Rams' last 4 Week 8 games. Find more NFL betting trends for Chargers vs. Rams.
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How to watch Chargers vs Rams
| Location | SoFi Stadium, Inglewood, California |
| Date | Sunday, Nov. 1, 2026 |
| Kickoff | 4:05 p.m. ET |
| TV | Fox |
Chargers vs Rams latest injuries
Check out our NFL injuries page for updates on every team.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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