Panthers vs Penguins Prediction, Picks & Combo for Tonight’s NHL Game

Neil Parker - Analyst at Covers.com
Neil Parker • Betting Analyst 16+ years betting experience
Updated: Oct 22, 2026 , 03:17 PM ET • 4 min read

The reeling Penguins will have no answers for the Panthers tonight.

nhl

Match starts: 19 mins
Panthers vs. Penguins prediction, NHL, Florida Panthers, Matthew Tkachuk, Brady Tkachuk, Sam Reinhart, Seth Jones
Photo By - Reuters Connect. Sam Reinhart of the Florida Panthers and Sidney Crosby of the Pittsburgh Penguins.

The Florida Panthers and Pittsburgh Penguins are trading near a pick’em ahead of their 7 p.m. ET puck drop at PPG Paints Arena on Thursday, Oct. 22.

With Pittsburgh on a 1-6-1 slide, my favorite Panthers vs. Penguins prediction and NHL picks are calling for Florida to win for the fourth time in five games tonight. 

 TOP PICK
Panthers vs Penguins prediction: Panthers moneyline

The Pittsburgh Penguins can’t buy a save and have dropped four straight, with a minus-7 goal differential and an .821 team save percentage at five-on-five.

This is a rebound spot for a deeper and more talented Florida Panthers roster, and the Cats have been a 5-on-5 machine again to start the year, with a third-ranked Corsi For percentage and fourth-ranked expected goal percentage.

Pittsburgh and its injury-riddled blue line have skyrocketed to 3.7 goals against per game to rank 27th in the league, while starting netminder Arturs Silovs also sports a disastrous .676 SV% against high-danger shots.

These are serious weaknesses, so I recommend the Panthers moneyline up to 52%.

Covers COVERS INTEL: The Florida Panthers have allowed the fewest expected goals per 60 minutes at five-on-five.

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Panthers vs Penguins combo

Florida star Matthew Tkachuk has gone five straight games without a goal despite his prominent offensive role, generating 1.02 individual expected goals and 13 scoring chances during that stretch.

Playing alongside center Sam Bennett, Tkachuk has been on the ice for 5.49 goals per 60 minutes and a 60.8 CF% at five-on-five, putting the duo in a great position to torch Pittsburgh's struggling defense and goaltending.

Panthers vs Penguins combo

  • Panthers moneyline
  • Matthew Tkachuk 1+ goals
  • Sam Bennett 1+ points

Panthers vs Penguins player prop: Cooper Black 24+ saves

With the Panthers allowing the fewest expected goals per 60 minutes at 5-on-5, Florida rookie Cooper Black is well insulated for his first career start.

He posted a high-end .919 SV% across three AHL starts prior to being called up to Florida, and I’m expecting him to stand tall tonight.

Black is a towering 6-foot-8 and catches right-handed, so he’ll give the Pens a unique look between the pipes, and Panthers head coach Paul Maurice is excited about his athleticism.

I recommend this saves prop up to 55%.

Panthers vs Penguins goal scorer: Matthew Tkachuk

This goal prop is in play up to 35% because Tkachuk’s 14.3% shooting percentage is identical to the 14.3% mark he posted over the previous two seasons, and his offensive role positions him to continue generating high-quality scoring chances.

Of course, the Penguins have also surrendered 21 goals across their past four games.

Neil Parker's 2026 Transparency Record
  • Top picks: 21-12, +14.59 units
  • Combos: 2-12, -5.08 units
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Panthers vs Penguins odds

For help understanding probabilities, see our odds calculator.

  • Moneyline: Panthers 49% | Penguins 52%
  • Over/Under: Over 6.5 (54%) | Under 6.5 (47%)
  • Spread: Panthers +1.5 (69%) | Penguins -1.5 (32%)

For the full slate of NHL matchups, check out our NHL odds board!

Panthers vs Penguins trend

Pittsburgh has lost seven of its past eight games. Find more NHL betting trends.

How to watch Panthers vs Penguins

Location PPG Paints Arena, Pittsburgh
Date Thursday, Oct. 22, 2026
Puck drop 7 p.m. ET
TV SN-PIT, Sportsnet+

Panthers vs Penguins latest injuries

Check out our NHL injuries page for updates on every team. 

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Neil Parker - Covers
Betting Analyst

Neil Parker is, first and foremost, a sports fan. A huge supporter of the Cowboys, Cubs, and Maple Leafs, he has managed to parlay his passion into writing gigs at some of the top websites in the industry.

Neil takes a numbers-based approach to his handicapping and complements his in-depth statistical analysis with a keen eye on the markets to provide the best available odds. He loves to lean on his rolodex of idioms to offset his inner nerd. When it comes to wagering, he throws down on anything that catches his eye at bet365, Betway and BetVictor. He also keeps a close eye on CoolBet because the polar bear brand often has outlier NHL and NFL moneyline prices.

Neil graduated with honors from St. Thomas University in 2007 before completing his BEd at Acadia University in 2010. After teaching a myriad of courses and subjects, he found a groove delivering fun lessons to exceptional learners in non-traditional classroom environments. If his decade-plus teaching run taught him anything about sports betting, it’s to stay the course and use the summer – or offseason – to refresh and prepare to be better in the year to come.

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