20:15 ETOct 2

SF 8.5 o44.0

LA -8.5 u44.0

9:30 ETOct 5

MIN -3.5 o36.0

CLE 3.5 u36.0

13:00 ETOct 5

DAL -2.5 o47.5

NYJ 2.5 u47.5

13:00 ETOct 5

DEN 3.5 o43.5

PHI -3.5 u43.5

13:00 ETOct 5

HOU -1.0 o40.0

BAL 1.0 u40.0

13:00 ETOct 5

NYG 2.5 o42.0

NO -2.5 u42.0

13:00 ETOct 5

LV 7.0 o48.5

IND -7.0 u48.5

13:00 ETOct 5

MIA -1.0 o44.5

CAR 1.0 u44.5

16:05 ETOct 5

TB 3.5 o44.5

SEA -3.5 u44.5

16:05 ETOct 5

TEN 7.5 o41.5

ARI -7.5 u41.5

16:25 ETOct 5

WAS 3.0 o48.0

LAC -3.0 u48.0

16:25 ETOct 5

DET -10.5 o49.5

CIN 10.5 u49.5

20:20 ETOct 5

NE 8.0 o48.5

BUF -8.0 u48.5

20:15 ETOct 6

KC -3.5 o45.5

JAC 3.5 u45.5

Houston 3rd AFC South1-3

Jacksonville 2nd AFC South3-1

1:00PM ET Sep 21, 2025

CBS

Houston @ Jacksonville Odds

Pregame Odds	SPREAD
	HOU	JAC
	+1.0-112	-1.0-123
	+6.5+130	-6.5-196
	+1.5-116	-1.5+102

	TOTAL
	Over	Under
	--	--
	o45.5+129	u45.5-170
	o42.5-110	u42.5-103

	MONEYLINE
	HOU	JAC
	-105	-132
	+150	-10000
	-101	-112

Matchup | Picks | Projections | Line Movement

Houston @ Jacksonville Odds

Pregame Odds

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