Raiders vs Patriots Predictions, Picks & Best Bets for NFL Week 1

The Las Vegas Raiders beefed up their roster in the offseason, and our expert NFL predictions expect the Raiders to slip past Drake Maye and the Patriots.

Sam Farley - Contributor at Covers.com
Sam Farley • Betting Analyst
Sep 5, 2025 • 15:28 ET • 4 min read

NFL

Match starts: 42 hrs
NE
57 %
LV
43 %
EXPERT PICK - MONEYLINE
Las Vegas +114 Las Vegas +114
Read Analysis
Maxx Crosby of the Las Vegas Raiders
Photo By - Imagn Images. Maxx Crosby of the Las Vegas Raiders.

It’s the first Sunday of the season, and in the Las Vegas Raiders and New England Patriots, we get a chance to see two teams that are both tracking to ascend this season. 

There have been significant changes in the Raiders organization during the offseason, both in staffing and personnel, and our Raiders vs. Patriots predictions expect them to get off to a winning start.

Read on for my NFL picks for Sunday, September 7. 

Raiders vs Patriots prediction

Raiders vs Patriots Best bet: Las Vegas Raiders moneyline (+114)

The New England Patriots are a team who are steadily improving, with Drake Maye showing real glimpses of being a franchise quarterback last year. There’s valid optimism that they’ve found their post-Brady QB. 

May should improve in his second year, but while they’ve added some talent onto the roster, it’s still looking like a tough ask for new defensive coordinator Terrell Williams to hugely improve a defense that ranked third last in defensive DVOA last year.

For the Las Vegas Raiders, this feels like a watershed moment. In one offseason, they’ve added an experienced Super Bowl-winning head coach and a man who can truly change the team's culture. 

They’ve now got a very good signal caller in Geno Smith and somebody with the talent to lead this offense, as well as drafting Ashton Jeanty, the running back who tore up college football last year.

Combine that with elite lynchpins in Maxx Crosby and Brock Bowers on both sides of the ball, and you have a team ready to improve and improve very quickly.

Raiders vs Patriots same-game parlay

In addition to our best bet for the game, we’re also going to Ashton Jeanty to score his first NFL touchdown. He had 30 touchdowns for Boise State last season and given the importance of the run to Pete Carroll teams, he should have plenty of opportunity.

The second leg of this SGP is for Brock Bowers to have seven or more receptions. He had seven or more targets in six of eight games post-Week 10 bye last year, and with Amari Cooper retiring, a barren WR corps, and an upgrade at QB, we should see a big game from Bowers.

Raiders vs Patriots 3-Leg SGP

  • Las Vegas Raiders moneyline (+114)
  • Ashton Jeanty anytime touchdown (-145)
  • Brock Bowers Over 6.5 receptions (+112)

Our big-ticket SGP: Raiders Romp!

Our lottery same-game parlay is going big by adding two legs to our above SGP.

First up, we’re backing TreVeyon Henderson to score. He looked exceptionally dangerous in preseason and adds real explosion to the Patriots’ offense.

We’re also backing Drake Maye to have Over 29.5 rushing yards. If you remove the Week 18 game in which he was only on the field briefly, he’s had 30 or more rushing yards in three of his past four games.

Raiders vs Patriots 5-Leg SGP

  • Las Vegas Raiders moneyline (+114)
  • Ashton Jeanty anytime touchdown (-145)
  • Brock Bowers Over 6.5 receptions (+112)
  • TreVeyon Henderson anytime touchdown (+130)
  • Drake Maye Over 29.5 rushing yards (-114)

Raiders vs Patriots odds

  • Spread: Raiders +2.5 (-110) | Patriots -2.5 (-110)
  • Moneyline: Raiders +120 | Patriots -140
  • Over/Under: Over 43.5 (-110) | Under 43.5 (-110)

More NFL picks and odds from Covers


Raiders vs Patriots trend to know

The Patriots' moneyline has only hit in six of their previous 21 games. Find more NFL betting trends for the Raiders vs. Patriots.

How to watch Raiders vs Patriots

Location Gillette Stadium, Foxborough, MA
Date Sunday, September 7, 2025
Kickoff 1:00 p.m. ET
TV CBS

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Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Sam Farley
Betting Analyst

Sam is based in the United Kingdom, where he grew up living and breathing soccer, before discovering - and playing - a different kind of football at the University of Bristol. He’s worked in the media covering soccer and the NFL for the better part of a decade, and has been a regular on the Matchbook NFL Podcast. His work has also appeared in a wide range of publications including The Telegraph, The Independent, VICE, and MSN.

The search for great betting value is a daily one, and Sam always hunts out big prices with a particular focus on player props. Sam’s best advice for bettors is to track their bets on a spreadsheet, that way you can keep an eye on your P&L but also the types of bets and sports that you are most successful in. He also recommends using a variety of different sportsbooks, with bet365, Betfair and Paddy Power amongst his favorites.

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