The Houston Texans return from last weekend's international trip to London to host the New York Giants in Week 7.
Houston is favored by 10.5 points, with the total set at 42.5 points. Kickoff is scheduled for 1 p.m. ET on FOX from Reliant Stadium in Houston, Texas.
My Giants vs. Texans prediction and NFL picks put a premium on points in this matchup.
TOP Pick
Giants vs Texans prediction: Under 42.5
Playable to 51%.
J.J. McCarthy had 243 passing yards in the fourth quarter last weekend against the Saints, but he entered the game with the Giants down 34-10 with 11:25 remaining.
New Orleans mostly played prevent defense late in the contest, but McCarthy still threw an interception and completed only 52.4% of his passes.
McCarthy nearly threw a second interception in the end zone on his second drive, then had two more interception-worthy throws on New York's subsequent drive.
McCarthy played 10 games in 2025, finishing with a negative EPA/play in seven. The three games with a positive EPA/play came against the Packers, Cowboys, and Commanders, defenses that ranked 22nd, 30th, and 31st in EPA/play allowed against the pass, respectively.
The Texans rank 8th in my schedule-adjusted defensive EPA/play ratings this season and 4th in schedule-adjusted defensive success rate. It's difficult to see the Giants scoring enough points to push this game over the total.
COVERS INTEL: C.J. Stroud leads all qualified quarterbacks with a 9.1% Completion Percentage Over Expected (CPOE) in 2026. The Giants defense has allowed the third-highest CPOE to opposing quarterbacks through six weeks.
Giants vs Texans combo
Playable to 28%.
Teams returning from an international trip without a bye week to recover from the travel always raise some concern, but Houston is simply a far superior team to New York.
A Nico Collins touchdown and a J.J. McCarthy interception both correlate well with an outright Texans win for those looking for a combo in this matchup.
Giants vs Texans combo
- Houston Texans Moneyline
- Nico Collins 1+ Touchdown
- J.J. McCarthy 1+ Interception
Giants vs Texans touchdown scorer: Nico Collins
Playable to 44%.
Cornerback Greg Newsome II has been ruled out against the Texans after missing Friday's practice.
He's played a team-high 286 snaps out wide for New York's defense in 2026, making him a big loss for a secondary unit that already ranks worse than the league average in EPA/play and success rate against the pass.
Nico Collins led the Texans in routes run and first-read targets in Week 6 against the Jaguars. This is an extremely favorable matchup for Collins, who has caught three touchdowns in four games this season.
- Top picks: 1-3, -2.00 units
- Combos: 1-3, +0.17 units
Giants vs Texans odds
For help understanding probabilities, see our odds calculator.
- Spread: Giants +10.5 | Texans -10.5
- Over/Under: Over 42.5 (52%) | Under 42.5 (49%)
- Moneyline: Giants 20% | Texans 81%
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Giants vs Texans weather
Reliant Stadium has a retractable roof, but it's been closed for 91% of Texans home games since 2010. It's relatively safe to assume it will be closed again this weekend.
Check out our NFL weather page for up-to-date info on every matchup.
Giants vs Texans trend to know
Under is 4-0-1 in Texans' last 5 games after allowing more than 30 points in their previous game. Find more NFL betting trends for Giants vs. Texans.
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How to watch Giants vs Texans
| Location | Reliant Stadium, Houston, Texas |
| Date | Sunday, Oct. 25, 2026 |
| Kickoff | 1 p.m. ET |
| TV | FOX |
Giants vs Texans latest injuries
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