Colts vs Chiefs Computer Picks: Our Best Week 2 Player Prop Projections

Chris Gregory - Betting Analyst at Covers.com
Chris Gregory • Betting Analyst 5+ years betting experience
Updated: Sep 20, 2026 , 01:00 PM ET • 4 min read

Patrick Mahomes looked eager to run in Week 1 and could be crossing the goal line once more against a team that allowed 41 points last week.

Patrick Mahomes Kansas City Chiefs NFL
Photo By - Reuters Connect. Patrick Mahomes during Kansas City's Week 1 over the Broncos.

The Kansas City Chiefs play host to the Indianapolis Colts on Sunday Night Football, and anticipation is up after Patrick Mahomes led a lively Chiefs offense to a 31-10 blowout win over the Broncos in Week 1.

Our top Colts vs. Chiefs computer picks and NFL picks target Daniel Jones through the air, Patrick Mahomes on the ground, and more when the action gets underway at 8:20 p.m. ET on NBC.

For help understanding Kalshi probabilities, see our odds calculator.

Colts Colts Chiefs Chiefs
Daniel Jones o199.5 passing yards
58%
Patrick Mahomes u19.5 completions
46%
Daniel Jones o9.5 rushing yards
46%
Kenneth Walker o79.5 rushing yards
53%
Josh Downs o39.5 receiving yards
52%
Patrick Mahomes anytime touchdown
21%
Alec Pierce o39.5 receiving yards
54%
Rashee Rice anytime touchdown
39%

Percentages courtesy of Kalshi, one of the best prediction market apps.

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Colts computer picks

Daniel Jones Over 199.5 passing yards

Projection: 225.39 passing yards

This is a juiced number, but with 25+ yards of leeway and the Colts expected to be trailing at Arrowhead Stadium, there will be plenty of chances for Daniel Jones to rack up passing yards. He cleared this number in 10 straight games to start last season.

🔥 Trade JONES passing yards now

Daniel Jones Over 9.5 rushing yards

Projection: 20.48 rushing yards

This is one of the best projections on the board, with Jones expected to run for more than double his 9.5-yard total. He also ran for 16 yards on three carries in last season's meeting with the Chiefs.

🔥 Trade Jones rushing yards now

Josh Downs Over 39.5 receiving yards

Projection: 50.83 receiving yards

With projections high on Jones and this Colts passing attack, it's not surprising to see the projections looking fondly at Indy's top pass-catchers. That starts with Josh Downs, who had 37 yards on just two catches despite the Colts only throwing for 166 yards in Week 1.

🔥 Trade downs receiving yards now

Alec Pierce Over 39.5 receiving yards

Projection: 58.63 receiving yards

The projections like Alec Pierce even more. There's nearly a 20-yard gap between his projection and this total, and he caught four balls for 61 yards against the Ravens in Week 1.

🔥 Trade Pierce receiving yards now

Chiefs computer picks

Patrick Mahomes Under 19.5 completions

Projection: 18.33 completions

This is only a slight lean to the Under, but Patrick Mahomes had just 15 completions in Week 1, and if the Chiefs can build a lead again, they'll be happy to continue handing the ball off to Kenneth Walker.

🏈 trade Mahomes completions now

Kenneth Walker Over 79.5 rushing yards

Projection: 81.37 rushing yards

Speaking of Kenneth Walker, he exploded for 173 rushing yards on 23 carries last week, and Derrick Henry did similar things to this Colts defense in Week 1, rumbling for 144 yards and three touchdowns on 24 carries. 

🔥 Trade Walker rushing yards now

Patrick Mahomes anytime touchdown

Projection: 0.33 touchdowns

Mahomes scored the first touchdown of the Chiefs' season last week and didn't seem bothered by his knee surgery. He ran seven times for 23 yards and will continue to be a threat once KC gets close to the goal line.

🔥 Trade Mahomes touchdown now

Rashee Rice anytime touchdown

Projection: 0.52 touchdowns

With this projection at 0.52 touchdowns, getting Rashee Rice to score a touchdown at anything below 45% presents some hard-to-turn-down value. He found the end zone despite a quiet overall game last week, and we're fetching him at 39% to score against a team that gave up 41 points in Week 1.

🔥 Trade Rice touchdown now

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Chris Gregory Covers.com
Betting Analyst

In his four years on the Covers editorial team, Chris Gregory has helped bolster the site’s golf and college football coverage. He brings a journalism and marketing background to his work as a Publishing Editor and can be found across our site covering the Masters, college football futures, and more.

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