The Pittsburgh Pirates will attempt a series sweep of their NL Central rival, the Milwaukee Brewers, when the teams meet this afternoon.
My Pirates vs. Brewers predictions expect Pittsburgh to sweep a series in Milwaukee for the first time in a decade.
Find out why in my MLB picks for Sunday, April 26.
Who will win Pirates vs Brewers today: Pirates (+107)
Carmen Mlodzinski takes the bump for the Pittsburgh Pirates, and he’s shown improvement in his arsenal. His split-finger usage has nearly doubled from last year, a key reason he’s ranked in the 91st percentile in barrel rate.
Mlodzinski faces a Milwaukee Brewers lineup that’s posted a .074 ISO and a 76 wRC+ over the last two weeks, ranking dead-last in both metrics.
Kyle Harrison is prime for some regression, given his ERA of 3.06 is far exceeding his 4.41 xERA. Pittsburgh’s bullpen also has the fourth-best xERA over the past two weeks and will close out the win.

Pirates vs Brewers Over/Under pick: Under 7.5 (-110)
We were unfortunate to hit the Under yesterday, with the game tied at 3-3 heading into extra innings. That said, we take that route again today.
Harrison is getting strikeouts on a consistent basis, an area where the top of Pittsburgh’s lineup has struggled at times.
The Pirates rank sixth in strikeout rate over the past two weeks, which has negated their high BABIP. They’re also right at 100 in wRC+ in that span.
The Brewers have scored just nine runs in their last four games, and their struggles at the plate will help keep this score low.
- ML/RL bets: 1-4, -3.50 units
- Over/Under bets: 4-1, +2.91 units
Pirates vs Brewers odds
- Moneyline: Pirates +108 | Brewers -113
- Run line: Pirates +1.5 (-194) | Brewers -1.5 (+186)
- Over/Under: Over 7.5 (-104) | Under 7.5 (+100)
Pirates vs Brewers trend
The Pittsburgh Pirates have hit the run line in 15 of their last 22 games (+9.65 Units / 34% ROI). Find more MLB betting trends for Pirates vs. Brewers.
How to watch Pirates vs Brewers and game info
| Location | American Family Field, Milwaukee, WI |
| Date | Sunday, April 26, 2026 |
| First pitch | 2:10 p.m. ET |
| TV | SNP, Brewers.TV |
| Pirates starting pitcher | Carmen Mlodzinski (1-1, 3.28 ERA) |
| Brewers starting pitcher | Kyle Harrison (1-1, 3.06 ERA) |
Pirates vs Brewers latest injuries
Pirates vs Brewers weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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