Baltimore Orioles starter Chris Bassitt has been crushed by left-handed hitters this season, and the Toronto Blue Jays’ lefty-heavy lineup is positioned to exploit that weakness again tonight in Baltimore.
That sets up well for Bassitt to go Over his 2.5 earned runs total tonight, which is my best bet for my Blue Jays vs Orioles predictions and MLB picks for Thursday, May 28.
Blue Jays vs Orioles predictions
Blue Jays vs Orioles best bet: Chris Bassitt Over 2.5 earned runs (Odds)
Chris Bassitt’s transition to the Baltimore Orioles has been disastrous.
The veteran righty owns a 5.51 ERA through his first 10 outings in orange, while ranking in the 9th percentile in opponent xBA.
Opponents are consistently squaring Bassitt up this season as he owns a .311 opponent batting average, while exceeding tonight’s earned runs total in four of his last six starts.
Additionally, the Toronto Blue Jays feature a heavy left-handed-hitting lineup that matches up well against Bassitt, who owns a .917 opponent OPS against lefties this season.
COVERS INTEL: Bassitt owns a 37% hard-hit rate.
Blue Jays vs Orioles same-game parlay (SGP)
Daulton Varsho profiles as a strong contender to punish Bassitt today as a left-handed slugger who crushes the sinker. As mentioned before, Bassitt owns a .917 OSP against lefties this year, and the sinker-ball in particular has been victimized.
Despite owning a .373 average on the pitch, Bassitt throws it more than any other pitch in his arsenal
This is where Varsho profiles well, owning a .394 average against the sinker with a 50% hard hit rate. So I'll take Over 0.5 hits for Varsho tonight.
I’ll also target Kazuma Okamoto Over 0.5 hits. The Jays' third baseman has crushed the sinker as well, owning a .444 average with a 62% hard-hit rate against the pitch.
Blue Jays vs Orioles SGP
- Chris Bassitt Over 2.5 earned runs
- Daulton Varsho Over 0.5 hits
- Kazuma Okamoto Over 0.5 hits
Blue Jays vs Orioles home run pick: Kazuma Okamoto (+540)
I'll make this wager a half unit, considering Bassitt has done a solid job of keeping the ball in the yard despite the rest of his struggles.
Kazuma Okamoto showed earlier in the season his homers can come in bunches, and after a go-ahead home run Wednesday afternoon, I'm banking on another long ball tonight in Baltimore.
Bassitt is throwing the sinker at a 48% rate to right-handed hitters, which plays to Okamoto's strengths. The Jays slugger owns a .506 slugging percentage and a 62% hard-hit rate against it.
- Best bets: 26-28, +2.10 units
- SGPs: 11-43, +5.60 units
- HR picks: 8-46, +0.15 units
Blue Jays vs Orioles odds
- Moneyline: Toronto +110 | Baltimore -130
- Run line: Toronto +1.5 (-175) | Baltimore -1.5 (+150)
- Over/Under: Over 8.5 (-120) | Under 8.5 (+100)
Blue Jays vs Orioles trend
The Over is 7-3 in the last 10 meetings between these two teams. Find more MLB betting trends for Blue Jays vs. Orioles.
How to watch Blue Jays vs Orioles and game info
| Location | Oriole Park at Camden Yards, Baltimore, MD |
| Date | Thursday, May 28, 2026 |
| First pitch | 6:35 p.m. ET |
| TV | SN, MASN |
| Blue Jays starting pitcher | Patrick Corbin (2-1, 3.86 ERA) |
| Orioles starting pitcher | Chris Bassitt (4-3, 5.51 ERA) |
Blue Jays vs Orioles latest injuries
Blue Jays vs Orioles weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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