NFL Picks Against the Spread for Every Week 18 Game

Chris Vasile breaks down his favorite NFL picks against the spread for Week 18, including the Carolina Panthers and Baltimore Ravens.

Chris Vasile - Betting Analyst at Covers.com
Chris Vasile • Betting Analyst
Dec 30, 2025 • 14:28 ET • 4 min read
Carolina Panthers quarterback Bryce Young (9) reacts after scoring a touchdown.
Photo By - Imagn Images. Carolina Panthers quarterback Bryce Young (9) reacts after scoring a touchdown.

We split 8–8 against the spread last week, but my Week 18 NFL picks bring maximum urgency with postseason implications across the board.

Some teams are playing for seeding, others for survival, and a few have nothing at stake — a key factor at the betting window.

Week 18 NFL picks against the spread

Matchup Pick
Panthers Panthers vs Buccaneers Buccaneers  Panthers (-3)
Seahawks Seahawks vs 49ers 49ers Seahawks (-1.5)
Saints Saints vs Falcons Falcons Falcons (-3)
Browns Browns vs Bengals Bengals  Bengals (-7.5)
Cowboys Cowboys vs Giants Giants  Giants (+4)
Packers Packers vs Vikings Vikings Vikings (-5.5)
Colts Colts vs Texans Texans Texans (-10.5)
Titans Titans vs Jaguars Jaguars Jaguars (-11.5)
Chiefs Chiefs vs Raiders Raiders Chiefs (-5.5)
Lions Lions vs Bears Bears Bears (-2.5)
Chargers Chargers vs Broncos Broncos Chargers (+11.5)
Dolphins Dolphins vs Patriots Patriots Patriots (-10.5)
Commanders Commanders vs Eagles Eagles Eagles (-7)
Cardinals Cardinals vs Rams Rams Cardinals (+7.5)
Jets Jets vs Bills Bills Bills (-7.5)
Ravens Ravens vs Steelers Steelers Ravens (-3.5)

Lines courtesy of FanDuel as of 12-30.

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Expert Week 18 NFL ATS picks

Panthers vs. Buccaneers: Panthers Panthers (-3)

The Buccaneers have dropped seven of their last eight games, yet have a chance to win the division. I cannot, in good faith, back that to happen. The Panthers' defense should do enough to win this game. 

Seahawks vs. 49ers: Seahawks Seahawks (-1.5)

The NFC West division title is at stake here, so give me the team that's been more consistent over the first 17 weeks of the season, and the one with the much better defense. 

Saints vs. Falcons: Falcons Falcons (-3)

I'm not entirely sure why the Falcons keep winning, but they've won three straight and have already screwed themselves out of a decent draft pick. Why not make it four on the trot vs. a bad Saints team? 

Browns vs. Bengals: Bengals Bengals (-7.5)

Joe Burrow or Shedeur Sanders? I know my answer. 

Cowboys vs. Giants: Giants Giants (+4)

This game should feature plenty of points, so I'll take the underdog here in a game that may come down to the last possession. 

Packers vs. Vikings: Vikings Vikings (-5.5)

The Packers may be without Jordan Love and Malik Willis for this game, which leaves Clayton Tune under center. That's not ideal. I'll take Max Brosmer in this spot with plenty of talent surrounding him. 

Colts vs. Texans: Texans Texans (-10.5)

The Texans' defense will likely eat Philip Rivers alive. Lay the points and don't think twice. 

Titans vs. Jaguars: Jaguars Jaguars (-11.5)

The Jaguars are one win away from clinching the AFC South. That's not a statement I thought I'd write this year, but c'est la vie. 

Chiefs vs. Raiders: Chiefs Chiefs (-5.5)

I want nothing to do with the Raiders, and neither should you. They stink, and the Chiefs should win this by a touchdown. 

Lions vs. Bears: Bears Bears (-2.5)

The Bears are playing for something, the Lions are not. The offense should do enough to beat an uninterested Lions squad at home. 


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Chargers vs. Broncos: Chargers Chargers (+11.5)

I still don't know if the Broncos are good or not. While they may yet secure the No. 1 seed in the AFC, the Chargers have enough offense to keep this one close. 

Dolphins vs. Patriots: Patriots Patriots (-10.5)

The Patriots have beaten up on bad teams all season, and the Miami Dolphins fit the bill. 

Commanders vs. Eagles: Eagles Eagles (-7)

The Eagles are fighting for the No. 2 seed, so this game should have their full attention.

Cardinals vs. Rams: Cardinals Cardinals (+7.5)

The Rams lost their outside chance at the division and, as such, are locked into a Wild-Card spot. With Matthew Stafford's MVP hopes all but dashed, I expect a vanilla game plan and the Cardinals to keep things close. 

Jets vs. Bills: Bills Bills (-7.5)

The Bills were a two-point conversion away from beating the Eagles despite playing poorly for 55 of the 60 minutes. I expect a much better effort here as they gear up for a Wild Card game next week. 

Ravens vs. Steelers: Ravens Ravens (-3.5)

There are two reasons I am picking the Ravens to cover. The first reason is I believe they're the better team from top to bottom. The second, I'm sitting on a "Steelers to miss the playoffs" ticket, which I would love to cash. 

My NFL ATS record is 118-120-2 this season for -9 units.

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Chris Vasile Covers.com
Betting Analyst

Chris Vasile has been in the betting industry for well over a decade, honing his craft as a writer, editor, and handicapper. Chris has contributed betting and non-betting content for online publications such as ProSportsDaily and The Hockey Writers, in addition to Covers. With a keen interest in soccer, Chris has been featured on Covers' 'Before You Bet', BetMGM Network, and SportsGrid. He also runs his own YouTube channel — Game Day Wagers.

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