It's a full-on football feast, and our NFL Week 2 parlays are here to help you make it a memorable weekend.
Check out our expert NFL picks and combo plays, featuring Ashton Jeanty and the Raiders taking down a shell-shocked Chargers squad.
NFL combo picks for Week 2
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| Matchup | Pick | |
|---|---|---|
vs |
Eagles -7.5 Smith 60+ receiving yards Wicks 24+ receiving yards |
5.50x |
vs |
Steelers +5.5 Rodgers 200+ passing yards Rodgers 22+ completions |
4.00x |
vs |
Bears moneyline Loveland anytime touchdown Jones Over 14.5 receiving yards |
7.30x |
vs |
Falcons +2.5 Under 43.5 Robinson 1+ TDs |
6.50x |
vs |
Jets +3.5 Hall anytime TD Hall Over 65.5 rushing yards |
4.50x |
vs |
Baltimore moneyline Henry anytime touchdown Shough Under 21.5 pass completions |
3.00x |
vs |
Under 45.5 Schultz Over 39.5 receiving yards Brown Anytime Touchdown: No |
5.00x |
vs |
Buccaneers -8.5 Mayfield Over 211.5 passing yards Egbuka Over 3.5 receptions |
5.77x |
vs |
Jaguars moneyline Tuten Over 51.5 rushing yards Waddle Over 50.5 receiving yards |
4.75x |
vs |
Raiders +6.5 Under 43.5 Jeanty Over 26.5 receiving yards |
6.50x |
vs |
Seattle moneyline Under 41.5 Harrison Jr. Under 34.5 receiving yards |
4.50x |
vs |
Over 44.5 Purdy 250+ Passing Yards Evans 50+ Receiving Yards |
5.29x |
vs |
Over 49.5 Lamb 1+ touchdown McLaurin 50+ receiving yards |
6.58x |
vs |
Under 46.5 Rice 1+ touchdown Jones 10+ rushing yards |
13.51x |
vs |
Parkinson TD Dart TD Likely Over 45.5 receiving yards |
24.00x |
Percentages courtesy of Kalshi, one of the best prediction market apps.
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Expert NFL combo picks for Week 2
Eagles vs. Titans: 5.50x
Eagles quarterback Jalen Hurts threw for 8.1 yards per attempt with a 10.9 aDoT and league-high 11.5% big-time-throw rate in Week 1, so I’m anticipating him having success through the air against a Tennessee defense that allowed the third-highest yards per reception (13.5) and fourth-highest catch percentage (84.6%) to wide receivers last week.
As a result, I’m expecting both Philly receivers DeVonta Smith and Dontayvion Wicks to leave a mark on this game. Smith finished the opener with a monster 16.4 aDoT, and Wicks was even higher with a 21.8 mark.
Check out Neil Parker's full Eagles vs. Titans predictions.
Steelers vs. Patriots: 4.00x
With the Steelers sending out a capable, experienced, and versatile defense, I’m happy to take the points in what I forecast to be a low-scoring game.
Additionally, while Rodgers’ surface numbers don’t jump off the page, he finished with the seventh-highest PFF offense grade among quarterbacks and didn’t have a single turnover-worthy play in Week 1.
Finally, I’m anticipating another busy day for the veteran QB through the air with a lot of quick looks in head coach and playcaller Mike McCarthy’s evolved West Coast offense.
Check out Neil Parker's full Steelers vs. Patriots predictions.
Vikings vs. Bears: 7.30x
I’m building this combo around Chicago and Caleb controlling the game. He and Ben Johnson can attack Minnesota’s vulnerable coverage through the middle, and ideally Loveland will capitalize with a touchdown catch.
If the Bears play from ahead, that should also help Vikings RB Aaron Jones Sr.’s receiving prop. With Vikings first-string RB Jordan Mason on IR, Jones should handle more passing-down work with Minnesota chasing points.
Check out Geoff Clark's full Vikings vs. Bears predictions.
Panthers vs. Falcons: 6.50x
The total is one of the lowest you’ll see, despite the Panthers setting opening-day points records on both sides of the ball. While Carolina could struggle to contain Robinson, the overall defense should be better. The Falcons with Rush at quarterback are far from the explosive offense of Ben Johnson and the Bears.
The Falcons’ defense should also have a better day than the Bears did against the Panthers. Atlanta allowed just 226 yards to the Steelers, its best opening-day performance since 1977. The Atlanta defense leads the NFL in total EPA and success rate.
Robinson is used to facing the Panthers. In six career games against Carolina, he has averaged 5.3 yards per carry and 85 rushing yards per game. Those numbers have improved to 5.6 yards per carry and 110 yards per game over the last two years.
Check out Quinn Allen's full Panthers vs. Falcons predictions.
Packers vs. Jets: 4.50x
For the Jets to get the cover on Sunday, they'll need another strong game out of Hall, and there's every reason to think he can deliver.
Beyond his strong performance in Week 1, Hall is also coming off of a 1,000-yard rushing season.
While the Green Bay defense was better than the 39 points it allowed to the Minnesota Vikings suggests, Minnesota still ran for two scores and 107 yards.
I'm not worried about Hall only totaling five scores last year, as this offense has much more ability to move the ball with Smith behind center.
There's outstanding value in backing Hall to hit his rushing total and get in the end zone combined with a Jets cover.
Check out Ed Scimia's full Packers vs. Jets predictions.
Saints vs. Ravens: 3.00x
I’m building this 3-leg combo around the Ravens winning at home and leaning on their ground game. Baltimore is an 8.5-point favorite, but rather than asking the Ravens to cover, I’m taking the higher-probability moneyline and pairing it with Derrick Henry to find the end zone.
The final leg is Tyler Shough Under 21.5 pass completions. Baltimore generated the NFL’s highest pressure rate in Week 1 without relying heavily on the blitz, which should make life difficult for Shough. Add in a windy forecast that could push both offenses toward the run, and I like the way these three legs work together.
Check out Geoff Clark's full Saints vs. Ravens predictions.
Bengals vs. Texans: 5.00x
This combo is built around Houston's defense controlling the game. The Under 45.5 is the foundation, especially with Collins out and Joe Burrow listed as questionable.
My "Chase Brown No anytime touchdown" leg works with the Under. Houston graded as one of the NFL's best run defenses in Week 1, while Cincinnati struggled to generate push up front. Meanwhile, Collins' absence should funnel more targets toward Schultz, and Cincinnati also allowed the most receiving yards to tight ends last year.
Check out Geoff Clark's full Bengals vs. Texans predictions.
Browns vs. Buccaneers: 5.77x
The Buccaneers shouldn't have any problems exploiting a poor Browns team, and a convincing win is in the cards for Mayfield and Co.
Speaking of Mayfield, he's a great look to throw for Over 200 yards. The QB had 216 yards through the air in Week 1, and the Browns allowed Trevor Lawrence to throw for 245 last weekend.
Mayfield was also substantially more efficient at home last season, averaging 230.9 yards per game compared to 205.1 on the road. Mayfield's passer rating was also stronger in Tampa.
Emeka Egbuka is arguably Mayfield's most important receiver, and the former Ohio State star reeled in five catches on six targets in the season opener.
Egbuka has all the ability to take advantage of Cleveland's shaky secondary, and he'll surely have a bigger role this season alongside Chris Godwin after Mike Evans' departure.
Check out Quinn Allen's full Browns vs. Buccaneers predictions.
Jaguars vs. Broncos: 4.75x
I’m so bullish on the Jaguars that in the combo, I want to include them on the moneyline and not just with the points. We saw how Kenneth Walker caused havoc for the Broncos' defense, racking up 173 yards on the ground, and Bhayshul Tuten can be encouraged by that given his tackle-breaking ability. Tuten led the Jags' backfield in the opener, outcarrying Chris Rodriguez 15 to 6 despite only having marginally more snaps, 48% to 41%. He did more with those opportunities, forcing five missed tackles.
Jaylen Waddle’s first game for the Broncos was about as bad as he could have hoped, catching just one of three targets for two yards. However, leading the Broncos with an 82% route participation rate is surely an indicator that he’ll continue to see volume, which should lead to more production.
Check out Sam Farley's full Jaguars vs. Broncos predictions.
Raiders vs. Chargers: 6.50x
Given the Chargers’ sloppy Week 1 outing and the likelihood that McConkey is either out or limited, I’m jumping on the Under, which was 11-6-1 for LA last season.
Equally, the Raiders’ steady offensive day against the tanking Miami Dolphins was hardly a stern test, and their own thin receiver depth will be tested here. The Under was 5-3 in Las Vegas’ eight road games in 2025.
The likeliest carryover from last weekend for the Raiders is Jeanty’s do-it-all role. He had 29 touches against Miami, including six catches for 45 yards and a pair of TDs, and I see Kubiak drawing up ways to get the ball into his best player’s hands.
Check out Tom Oldfield's full Raiders vs. Chargers predictions.
Seahawks vs. Cardinals: 4.50x
This combo is built around Seattle winning an ugly game rather than running away with it.
With Lock under center, I expect the Seahawks to play conservatively, shorten the game, and lean on a defense that looked dominant once Darnold went down last week. That obviously supports the Under. I'm using Seattle's moneyline instead of -3.5 because Lock makes laying more than a field goal tougher to justify.
Cardinals wide receiver Marvin Harrison Jr.'s Under 34.5 receiving yards fits the narrative. Arizona has several legitimate options to distribute targets to, and Harrison now draws a Seattle secondary that should be much tougher than the Chargers unit he faced last week.
Check out Geoff Clark's full Seahawks vs. Cardinals predictions.
Dolphins vs. 49ers: 4.29x
Brock Purdy thrived from a clean pocket in 2025, ranking third in EPA/dropback and second in Success Rate among 33 qualified quarterbacks. Miami's complete inability to generate defensive pressure against a weak Las Vegas offensive line in Week 1 doesn't bode well for their chances to get pressure on Purdy in Week 2.
Edge rusher Chop Robinson led the Dolphins in quick pressure rate last fall, but has been ruled out for Sunday's action due to a concussion. San Francisco should have plenty of time to find holes against a weak Miami secondary unit.
Mike Evans was a clear focal point for San Francisco's passing attack in their season opener, catching three passes and recording three first downs on the team's opening offensive drive. There is no player in Miami's secondary unit capable of covering Evans in man coverage, which should mean plenty of targets for San Francisco's top receiver.
Check out Nick Galaida's full Dolphins vs. 49ers predictions.
Commanders vs. Cowboys: 6.58x
We didn’t get a good look at either offense in Week 1. Dallas didn’t touch the ball, and Washington wasted an entire half before finding it form. Neither defense is drum tight, and the fast track inside Jerry’s World will help pump out plenty of points in Week 2.
CeeDee Lamb scored against New York and is excellent at adjusting and exploiting holes in blitzing defenses. Although Terry McLaurin couldn’t get going against a solid Eagles secondary, he'll shred the Cowboys' crappy coverage for at least 50 yards in Week 2.
Check out Jason Logan's full Commanders vs. Cowboys predictions.
Colts vs. Chiefs: 13.51x
With two run-centric offenses trying to grind out gains on the ground and control pace and clock, the Under holds the best value on Sunday Night Football. Indy will also have a tough time against this blitz-heavy defense from Kansas City. Mix in the potential for rainstorms, and points will be tough to come by.
That said, there can still be fireworks. Rashee Rice cashed in last week with a touchdown, and he can exploit a Colts coverage that struggles with slot receivers. On the other side, Daniel Jones will need to make plays with his legs to keep the chains moving and escape a relentless KC pass rush.
Giants vs. Rams: 24.00x
Colby Parkinson led the Rams' TE stable in snaps (75%) and routes (59%). He wasn't very active, but the entire offense struggled in Week 1. Only the Bills ran 3-TE sets at a higher rate than the Rams.
Jaxson Dart is moving well in the pocket and getting a great combination of scrambles and designed runs. Dart loves the bright lights.
Finally, Isaiah Likely's props have not adjusted to his new role in this offense. An indoor setting and a likely trailing game script only help.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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