Week 2 in the NFL features a Super Bowl rematch between the Philadelphia Eagles and the Kansas City Chiefs on Sunday.
Philly quarterback Jalen Hurts has been a touchdown machine, and my Eagles vs. Chiefs predictions are betting on him to get into the endzone once again.
Here are my best free NFL picks for this marquee matchup on September 14.
Eagles vs Chiefs prediction
Eagles vs Chiefs Best bet: Jalen Hurts anytime touchdown (-115)
Jalen Hurts rushed 14 times for 62 yards and a pair of touchdowns last week. The Philadelphia Eagles pivot has now scored a touchdown in 12 of his last 15 games, which includes the Super Bowl when he rumbled for 72 yards and a score against the Kansas City Chiefs.
Hurts has benefitted from playing behind a massive offensive line that drives defenders off the ball. He's practically unstoppable at the goal line thanks to the "tush push" that was nearly banned during the offseason.
Kansas City's defense looked vulnerable last week in Brazil, surrendering 27 points and ranking 30th in the league in defensive EPA. The Chiefs struggled to generate pressure outside of Chris Jones, and their secondary was torched by Justin Herbert.
Philly should be able to move the ball and get close to the end zone, where Hurts will punch it in.
Eagles vs Chiefs same-game parlay
Kansas City’s defense struggled last week, while the offense is short on playmakers with Rashee Rice suspended and Xavier Worthy sidelined. Philadelphia’s elite defense smothered Patrick Mahomes in the Super Bowl, and with Jalen Carter avoiding suspension, it should contain the Chiefs again.
The Chiefs have home-field advantage and a couple of extra days to prepare, but the Eagles are the better team on both sides of the ball.
With KC stacking the box to stop Saquon Barkley, Nick Sirianni will attack a vulnerable Chiefs secondary. Kansas City was 28th in the league in pressure rate and 30th in coverage grade in Week 1, which led to Justin Herbert throwing for 318 yards.
Sirianni loves to get his tight ends involved in the passing game, and Dallas Goedert led the Eagles with seven targets in Week 1. Goedert is doubtful for Sunday, meaning more work for No. 2 TE Grant Calcaterra.
Calcaterra will take advantage of a Chiefs D that allowed a league-high 70.1 yards per game to the position last year.
Eagles vs Chiefs 4-leg SGP
- Hurts anytime touchdown
- Eagles moneyline
- Hurts Over 208.5 passing yards
- Calcaterra Over 21.5 receiving yards
Our big-ticket SGP: Jammin' with JuJu
- With Worthy still injured, JuJu Smith-Schuster should have another productive game after hauling in five receptions for 55 yards last week.
Eagles vs Chiefs 5-leg SGP
- Hurts anytime touchdown
- Eagles moneyline
- Hurts Over 208.5 passing yards
- Calcaterra Over 21.5 receiving yards
- Smith-Schuster Over 33.5 receiving yards
Eagles vs Chiefs odds
- Spread: Eagles -1.5 (-105) | Chiefs -1.5 (+102)
- Moneyline: Eagles -116 | Chiefs -102
- Over/Under: Over 46.5 (-112) | Under 46.5 (-108)
More NFL picks and odds from Covers
Eagles vs Chiefs trend to know
The Eagles are 6-1 SU and ATS in their last seven games away from home. Find more NFL betting trends for Eagles vs. Chiefs.
How to watch Eagles vs Chiefs
| Location | GEHA Field at Arrowhead Stadium, Kansas City, MO |
| Date | Sunday, September 14, 2025 |
| Kickoff | 4:25 p.m. ET |
| TV | FOX |
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