The Arizona Cardinals and Tampa Bay Buccaneers have each lost three straight games, but something’s got to give when they clash at Raymond James Stadium on Sunday.
Jacoby Brissett has racked up a ton of passing yards as the Cardinals’ starting signal-caller, and my Cardinals vs. Buccaneers picks call for more of the same at Tampa.
Here are my best free NFL picks for this Week 13 showdown on November 30.
Cardinals vs Buccaneers prediction
Cardinals vs Buccaneers Best bet: Jacoby Brissett Over 266.5 passing yards (-114)
Jacoby Brissett has been a bright spot for the floundering Arizona Cardinals, and I expect him to keep slinging the ball in Sunday’s game against the Tampa Bay Buccaneers.
Since taking over as Arizona’s starting QB, Brissett has averaged 314.5 passing yards on 43.5 attempts per game across six contests. Brissett has passed for at least 300 yards three times, including each of his last two games.
He’s gone for no fewer than 258 yards in all six starts, and he’s hit the Over on this line four times.
Tampa Bay has been stingy against the run, allowing the seventh-fewest rushing yards per game at 97.6. The Bucs’ passing defense has been a bit easier to attack, surrendering the sixth-most yards at 243.5.
Arizona’s running backs have been banged up all season, so don’t expect the Cards to lean on the run game in this one. Brissett should continue to let it rip in a favorable defensive matchup.
Cardinals vs Buccaneers same-game parlay
Arizona has allowed 25.7 points per game, and Tampa Bay has allowed 25.8. Both defenses rank in the bottom eight in points allowed per game, so I expect a high-scoring matchup on Sunday.
The Cardinals have hit the Over in three straight and six of seven, and the Buccaneers have hit the Over in two of their last three.
Michael Wilson has been electric with Marvin Harrison Jr. (appendix) sidelined, going for at least 100 yards in back-to-back games. Even if MHJ is cleared to play on Sunday, Wilson should remain involved, and I'll bet on him reaching the endzone in a game filled with points.
Cardinals vs Buccaneers SGP
- Jacoby Brissett Over 266.5 passing yards
- Over 45.5
- Michael Wilson anytime touchdown
Our big-ticket SGP: Tez Dispenser!
The rookie out of Oregon was responsible for Tampa Bay’s only score of Week 12, and he’s hit paydirt five times across his last six games. Even with Chris Godwin back, Tez Johnson should be a significant factor in Tampa Bay’s passing attack.
Cardinals vs Buccaneers SGP
- Jacoby Brissett Over 266.5 passing yards
- Over 45.5
- Michael Wilson anytime touchdown
- Tez Johnson anytime touchdown
Cardinals vs Buccaneers odds
- Spread: Cardinals +6 (-110) | Buccaneers -6 (-110)
- Moneyline: Cardinals +225 | Buccaneers -275
- Over/Under: Over 49.5 (-110) | Under 49.5 (-110)
More NFL picks and odds from Covers
Cardinals vs Buccaneers trend to know
The Tampa Bay Buccaneers have hit the Game Total Over in 8 of their last 10 games at home (+5.80 Units / 53% ROI).. Find more NFL betting trends for Cardinals vs. Buccaneers.
How to watch Cardinals vs Buccaneers
| Location | Raymond James Stadium, Tampa, FL |
| Date | Sunday, November 30, 2025 |
| Kickoff | 1:00 p.m. ET |
| TV | FOX |
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