Oklahoma vs Missouri Predictions, Picks, and Best Bets: Sooner Rather Than Later

For as limited as Oklahoma has looked at times, the Sooners are 3-point road favorites against a Mizzou that could be down its starting quarterback. Read more in our college football picks below.

Eric Rosales - Betting Analyst at Covers.com
Eric Rosales • Betting Analyst
Nov 9, 2024 • 16:38 ET • 4 min read
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This article contains predictions for an old game!

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Jackson Arnold Oklahoma Sooners SEC college football
Photo By - Imagn Images. Jackson Arnold scrambling for the Oklahoma Sooners.

The math for the Oklahoma Sooners is simple. Win one of the next three matchups against SEC-ranked teams, and they guarantee a bowl game.

Their first shot comes tonight against the Missouri Tigers, and our Oklahoma vs. Missouri predictions expect the Sooenrs to deliver. 

Oklahoma vs Missouri prediction and best bet

My best bet
Oklahoma -3 (-110 at BetMGM)
Picks made at time of writing may not reflect live odds.

My analysis
The Missouri Tigers had their two-game win streak shattered with a 34-0 drubbing at the hands of then-15th-ranked Alabama. Not only did they get smacked around, but quarterback Brady Cook left for the second straight game with an injury and remains a question mark for this game. 

If he can’t play, former Notre Dame pivot Dew Pyne will get the start. He didn’t exactly rally the troops against the Crimson Tide, going 6-for-12 for 42 yards and three interceptions. It’s likely the Oklahoma Sooners will try to force Pyne to beat them with the pass, as OU’s run defense is 17th-best in the nation, holding teams to 106.1 yards per game.

Meanwhile, Jackson Arnold is on an upward trajectory after getting renamed the starter. He was solid in a 59-14 obliteration of Maine, going 15-for-21 for 224 yards and two TDs, helping OU bust out of a three-game losing skid.

Arnold now has four TD tosses and no interceptions in the last two games while completing passes at better than a 70% rate. If OU can welcome back pass catchers Jalil Farooq and Deion Burks from injury, that could really help its quarterback find a rhythm.  

Mizzou is not to be taken lightly on defense, though, as it holds opponents to under 300 yards of offense per game and boasts a Top-10 passing defense in college football, allowing just 164.8 yards per game.

Oklahoma vs Missouri same-game parlay (SGP)

Oklahoma -2.5

Theo Wease Jr. Over 39.5 receiving yards

Someone being undervalued is Mizzou receiver Theo Wease Jr., who had just two catches for 19 yards against Alabama, and now his line is set at 39.5 receiving yards — a number he'd passed in his previous six starts.

Pyne has something to do with this line, but if the backup pivot does get the start, he can’t be worse than he was last week — and neither will Wease Jr.

Learn how to bet a same-game parlay with these helpful tips and strategies.

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Oklahoma vs Missouri odds

Oklahoma vs Missouri live odds

Oklahoma vs Missouri opening odds

  • Oklahoma vs. Missouri spread: Missouri -2.5
  • Oklahoma vs. Missouri moneyline: Oklahoma +120, Missouri -140
  • Oklahoma vs. Missouri Over/Under: 42.5

Odds courtesy of BetMGM.

Oklahoma vs Missouri spread and Over/Under analysis

  • Mizzou has won each of its last 12 games against unranked opponents. 

  • Oklahoma is 3-1 ATS as a favorite this season.

  • The Over has cashed in three straight meetings, and Oklahoma's last four games against unranked opponents have gone Over the total.

Oklahoma vs Missouri betting trend to know

Oklahoma has cashed the first-ha;lf moneyline in six of its last 11 games for +6.25 units and a 14% ROI. Find more college football betting trends for Oklahoma vs Missouri.

Oklahoma vs Missouri game info

Location: Memorial Stadium, Columbia, MD
Date: Saturday, 11-9, 2024
Kickoff: 7:45 p.m. ET
TV: SEC Network

Oklahoma vs Missouri latest injuries

Oklahoma vs Missouri weather

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Eric Rosales - Covers
Betting Analyst

Eric has been involved in sports media in many different capacities since graduating from journalism school in 1999, back when getting your own column in a newspaper was still considered a thing. He doubled down and graduated from broadcast journalism school five years later, which led to a move to Toronto and a career with The Sports Network (TSN). From behind-the-scenes production work, he moved into the digital realm, where he had his own hoops column (At the Buzzer), while regularly live streaming and chatting with fans during broadcasts as the character known as LeBlog James. He was also a key contributor to TSN and CTV’s Olympic programming during the 2012 London Games.

Eric eventually found his way into the sports betting field in 2016 and has been a mainstay ever since. He was tagged on Twitter as a Top 10 NBA sharp during the 2021 season and has been interviewed about basketball and his handicapping process on shows from Vancouver to India. Eric is now a jack-of-all-sports at Covers, where his predictions span the alphabet soup: NFL, NBA, MLB, NHL, F1, WNBA, Euro, and Copa.

When making picks, he focuses on finding value first and foremost, and ensuring readers have all the information they need to make an informed choice.

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