In college football's marquee showdown of Week 1, I'm targeting a good matchup in the pass game in favor of Clemson and the mobility of LSU quarterback Sam Leavitt for the anytime touchdown markets.
Without further ado, let's look at Clemson vs. LSU touchdown picks for Saturday, Sept. 5, with kickoff set for 7:30 p.m. ET on ABC.
Best Clemson vs LSU anytime touchdown picks
For help understanding probabilities, please see our odds calculator.
| Pick |  Probability |
|---|---|
 Bryant Wesco Jr. anytime TD |
34% |
 Sam Leavitt anytime TD |
47% |
Percentages courtesy of ProphetX, one of the best prediction market apps.
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Clemson touchdown pick: Bryant Wesco Jr.
Clemson wideout Bryant Wesco Jr. was named to the All-ACC Preseason Football Team, and he is projected to line up across from P.J. Woodland, who is LSU's lowest-graded cornerback at Pro Football Focus.
According to 247Sports.com, Wesco was a four-star recruit coming out of high school, while Woodland was only a three-star recruit. More importantly, Wesco caught a team-high six touchdowns last season in only seven games.
LSU touchdown pick: Sam Leavitt
LSU quarterback Sam Leavitt has scampered for five touchdowns in each of the past two years. Meanwhile, Lane Kiffin loves to ask his quarterbacks to use their legs.
Kiffin coached the Ole Miss Rebels from 2020-25. Trinidad Chambliss rushed for eight scores last season, and former Rebels QB Jaxson Dart totaled 12 TDs in his three years as a starter for Kiffin.
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Clemson vs LSU touchdown combo
- Bryant Wesco Jr. anytime TD
- Sam Leavitt anytime TD
ProphetX combo probability: 15%
Leavitt has Heisman-winning potential, Wesco will be a future NFL wide receiver, and both will look to ball out on national television.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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