The New York Yankees took the first two games of this series, and they're -145 favorites to earn another win in Game 3.
With Cam Schlittler taking the mound, my Yankees vs. White Sox predictions and MLB picks believe the value again lies with the road team.
Who will win Yankees vs White Sox today: Yankees (-145)
Davis Martin has had a rough go of late. His ERA is 6.0 over the last 30 days, and his underlying numbers (5.45 xFIP, 5.69 SIERA) indicate the poor results are warranted.
It’ll be tough for him to get back on track against the New York Yankees. They rank second in ISO vs. right-handed pitching, and Martin’s ERA sits at 6.14 over seven starts against Top 10 opponents.
The Chicago White Sox will have a difficult time keeping up facing Cam Schlittler, who slots in the 99th percentile in Pitcher Run Value.
Back New York to -160.

Yankees vs White Sox Over/Under pick: Under 7.5 (-115)
Schlittler’s gotten dinged up a little more frequently of late, but his process is as strong as ever. He has struck out 32.2% of batters in his past five starts while posting a 2.80 xFIP.
His success should continue in Chicago. The White Sox rank 18th in average vs. righties this season, and 24th during the month of July.
It’s a struggle for them to string together hits, and Schlittler’s 0.83 HR/9 output doesn’t give them an escape via power.
If Martin doesn’t get blown up, this game should stay Under.
Bet to -120.
- ML/RL bets: 64-58, -7.05 units
- Over/Under bets: 67-50-5, +8.64 units
Yankees vs White Sox weather
Temperatures are expected to land in the low 70s with winds blowing east. No real impact.
Yankees vs White Sox odds
- Moneyline: Yankees -145 | White Sox +125
- Run line: Yankees -1.5 (+115) | White Sox +1.5 (-135)
- Over/Under: Over 7.5 (-110) | Under 7.5 (-110)
Yankees vs White Sox trend
New York has hit the game total Under in 13 of the last 19 games (+6.60 units, 31% ROI). Find more MLB betting trends for Yankees vs. White Sox.
How to watch Yankees vs White Sox and game info
| Location | Rate Field, Chicago, IL |
| Date | Wednesday, July 29, 2026 |
| First pitch | 7:40 p.m. ET |
| TV | Prime Video |
| Yankees starting pitcher | Cam Schlittler (10-6, 2.07 ERA) |
| White Sox starting pitcher | Davis Martin (9-5, 3.49 ERA) |
Yankees vs White Sox latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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