Red Sox vs Blue Jays Prediction, Odds & Home Run Pick for Today's MLB Game

Mike DiStefano - Contributor at Covers.com
Mike DiStefano • Betting Analyst 14+ years betting experience
Updated: Apr 29, 2026 , 09:34 AM ET • 4 min read

Brayan Bello has been one of the worst starting pitchers in MLB this season, which will be music to Vladimir Guerrero Jr.'s ears.

MLB

Match starts: 4 hrs
BOS
38 %
TOR
62 %
EXPERT PICK - PROP
Vladimir Guerrero Jr. o1.5  Total Bases (+115) Vladimir Guerrero Jr. o1.5 Total Bases (+115)
Read Analysis
Vladimir Guerrero Jr. Toronto Blue Jays MLB
Photo By - Reuters Connect. Toronto Blue Jays right fielder Jesús Sánchez (12) celebrates hitting a home run against the Cleveland Guardians with first baseman Vladimir Guerrero Jr. (27)

The value on Vladimir Guerrero Jr.’s base prop is too good to pass up with Bryan Bello on the mound for the Red Sox today. 
 
Read on to see why my Red Sox vs. Blue Jays predictions and MLB picks like Toronto's superstar on Wednesday, April 29.

Red Sox vs Blue Jays predictions

Red Sox vs Blue Jays best bet: Vladimir Guerrero Jr. Over 1.5 total bases (+115)

I was quite surprised to see Vladimir Guerrero Jr.’s total bases prop paying plus money to go Over 1.5 today.

Firstly, Vladdy is one of the hottest hitters in baseball, batting .378 over his last 10 games while averaging two bases per outing

I expect the Toronto Blue Jays slugger to continue swinging that hot bat tonight, too, especially with Bryan Bello on the mound for the Boston Red Sox.

Vladdy has crushed Bello throughout his career, going 12-for-30 with a 1.153 OPS and two homers.

It’s been a rough start to the season for Bello, who is 1-3 with a 9.00 ERA. Analytically, Bello has been one of the worst pitchers in baseball, ranking in the second percentile in xERA and a .314 xBA.

Covers COVERS INTEL: Bello has a 50% usage on his sinker to righties, which favors Vladdy and his .364 average against the pitch.

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Red Sox vs Blue Jays same-game parlay (SGP)

I’ll continue to fade Bello, and take Over 2.5 earned runs. He’s gone Over this mark in four of his five starts, averaging 4.4 runs allowed per game, and the Jays' lineup matches up well against him. 

Which leads me to why I like Over 0.5 runs for Vladdy today as well.

Firstly, he’s scored nine times in his last nine games. However, it’s Toronto’s .320 average against Bello that makes me believe Vlad will not only get on base, but his teammates will drive him in, too, especially with the 1.115 OPS he’s allowed through five starts this year. 

Red Sox vs Blue Jays SGP

  • Vladimir Guerrero Jr. Over 1.5 total bases
  • Vladimir Guerrero Jr. Over 0.5 runs
  • Brayan Bello Over 2.5 earned runs
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Red Sox vs Blue Jays home run pick: Vladimir Guerrero Jr. (+575)

75-100 words about the home run pick.

2026 Transparency record
  • Best bets: 9-19, -6.95 units
  • SGPs: 3-25, -12.25 units
  • HR picks: 5-23, -0.73 units

Red Sox vs Blue Jays odds

  • Moneyline: Boston +110 | Toronto -130
  • Run line: Boston +1.5 (-175) | Toronto -1.5 (+150)
  • Over/Under: Over 8.5 (-110) | Under 8.5 (-110)

Red Sox vs Blue Jays trend

The Toronto Blue Jays have hit the 1st Five Innings (F5) Team Total Under in 10 of their last 13 home games (+7.00 Units / 42% ROI). Find more MLB betting trends for Red Sox vs. Blue Jays.

How to watch Red Sox vs Blue Jays and game info

Location Rogers Centre, Toronto, ON
Date Wednesday, April 29, 2026
First pitch 3:07 p.m. ET
TV Sportsnet
Red Sox starting pitcher Brayan Bello
(1-3, 9.00 ERA)
Blue Jays starting pitcher Eric Lauer
(1-3, 6.75 ERA)

Red Sox vs Blue Jays latest injuries

Red Sox vs Blue Jays weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Mike DiStefano - Covers
Betting Analyst

Mike DiStefano joins Covers after a successful five-year stint with TSN. Distefano hosted Leafs Lunch, a Toronto Maple Leafs-centric radio show which featured a daily best bets segment where he found the biggest and best value plays of the night. He was also a weekly staple on TSN's flagship radio/tv show "OverDrive" as a betting analyst during their NFL picks segment #TeamAl-DogForever.

A graduate of Centennial College’s Sports Journalism program, Mike has also contributed to the Canadian Baseball Network, FanSided, and The Hockey News.

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