Guardians vs Blue Jays Prediction, Odds & Home Run Pick for Tonight's MLB Game

Mike DiStefano - Contributor at Covers.com
Mike DiStefano • Betting Analyst 14+ years betting experience
Updated: Apr 24, 2026 , 10:37 AM ET • 4 min read

DiStefano's Prediction: Expect Ernie Clement's hot bat to continue tonight.

MLB

Match starts: 6 hrs
CLE
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TOR
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Ernie Clement of the Toronto Blue Jays MLB
Photo By - Reuters Connect. Ernie Clement of the Toronto Blue Jays MLB

Toronto Blue Jays infielder Ernie Clement has been Mr. Consistent this season, picking up where he left off in October. 

He is sitting just one hit shy of the MLB hits lead, and I’ll bet on him closing the gap tonight with another big game at the plate against the Cleveland Guardians. 

Read on to see why in my Blue Jays vs. Guardians predictions and free MLB picks for April 24. 

Guardians vs Blue Jays predictions

Guardians vs Blue Jays best bet: Ernie Clement O 1.5 total bases (+120)

Ernie Clement has picked up where he left off last postseason, currently sitting one hit shy of the MLB lead, while averaging 1.75 bases per game so far this season 

He’s had multiple hits in four of his last five, averaging 2.8 bases per game in that stretch

Additionally, the pitching matchup favors Clement tonight. 

Cleveland Guardians starter Gavin Williams throws a heavy dose of the sweeper to right-handed batters, and it’s gotten him a lot of swing and miss this season. 

Clement has just a 17% whiff rate against the sweeper this season, with a .444 average against the pitch. 

Covers COVERS INTEL: Clement is hitting .417 with four XBH in five games since being moved into the two-hole of the Jays' lineup. 

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Guardians vs Blue Jays same-game parlay (SGP)

Nathan Lukes is starting to swing the bat well after a slow start to the season. He has a hit in four of his last five games with a 1.132 OPS in that stretch. 

Lastly, I’ll take Over 1.5 walks for Williams. The Cleveland starter ranks in the 13th percentile in walk rate, averaging 3.4 walks per game this season. The Jays' lineup as a whole owns a combined .410 OBP against him with five walks in just 34 at-bats. 

Guardians vs Blue Jays SGP

  • Ernie Clement Over 1.5 bases
  • Nathan Lukes Over 0.5 hits
  • Gavin Williams Over 1.5 walks
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Guardians vs Blue Jays home run pick: Vladimir Guerrero Jr. (+510)

I’ll make this a half-unit wager.

Firstly, if Lenyn Sosa gets a start today and a home-run market pops up for him, I’d sprinkle a little there. He leads the Jays in hard-hit rate and is 4-for-6 with two home runs against Williams in his career.

However, my official home run pick will be Vladimir Guerrero Jr., who owns a 1.319 OPS against Williams himself. 

It’s a good matchup for Guerrero, too, as Williams gives up a lot of hard contact with a 48.3% hard-hit rate, while ranking in the 7th percentile in average exit velocity. 

Additionally, Williams has given up one home run in four of his five starts this season. 

Mike DiStefano's 2026 Transparency record
  • Best bets: 5-18, -10.35 units
  • SGPs: 2-21, -13.50 units
  • HR picks: 4-19 -0.85 units

Guardians vs Blue Jays odds

  • Moneyline: Cleveland -126 | Toronto +108
  • Run line: Cleveland -1.5 (+124) | Toronto +1.5 (-160)
  • Over/Under: Over 8 (-105) | Under 8 (-115)

Guardians vs Blue Jays trend


The Toronto Blue Jays have hit the 1st Five Innings (F5) Team Total Under in 11 of their last 15 games at home (+6.65 Units / 37% ROI). Find more MLB betting trends for Guardians vs. Blue Jays.

How to watch Guardians vs Blue Jays and game info

Location Rogers Centre, Toronto, ON
Date Friday, April 24, 2026
First pitch 7:07 p.m. ET
TV Sportsnet One
Guardians starting pitcher Gavin Williams
(3-1, 2.12 ERA)
Blue Jays starting pitcher Max Scherzer
(1-2, 7.16 ERA)

Guardians vs Blue Jays latest injuries

Guardians vs Blue Jays weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Mike DiStefano - Covers
Betting Analyst

Mike DiStefano joins Covers after a successful five-year stint with TSN. Distefano hosted Leafs Lunch, a Toronto Maple Leafs-centric radio show which featured a daily best bets segment where he found the biggest and best value plays of the night. He was also a weekly staple on TSN's flagship radio/tv show "OverDrive" as a betting analyst during their NFL picks segment #TeamAl-DogForever.

A graduate of Centennial College’s Sports Journalism program, Mike has also contributed to the Canadian Baseball Network, FanSided, and The Hockey News.

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