The Toronto Blue Jays look to get back into the win column tonight when they enter their series opener against the Athletics at Sutter Health Park as -210 favorites.
Dylan Cease gets the ball for the Jays, which is the major reason why my Blue Jays vs. Athletics predictions and MLB picks are high on Toronto.
Blue Jays vs A's predictions
Blue Jays vs A's best bet: Blue Jays -1.5 (-115)
Dylan Cease has been in the AL Cy Young conversation all season, but he’s been on another level in the second half.
Since July 1, the Toronto Blue Jays ace leads all MLB starters in ERA (1.36) while also ranking second in xERA (2.37) and seventh in K/9 (11.47).
On the other side, Jacob Lopez has been solid for the Athletics (3.40 xERA; 79th percentile), but he’s averaging less than five innings per appearance. He’ll be backed up by the worst bullpen in the majors (5.45), which is where the Blue Jays can do their damage.
Play the Jays run line up to -120.

Blue Jays vs A's same-game parlay (SGP)
Cease is third in the majors with 221 Ks this season and has recorded at least eight punchouts in 14 of his last 19 starts.
Kazuma Okamoto has been mashing vs. left-handed pitching since Aug. 1 and will enjoy the platoon advantage today. Okamoto leads the Jays in SLG (.684) and OPS (1.056) vs. southpaws over that span, with nine of his 11 hits being for extra bases.
Blue Jays vs A's SGP
- Blue Jays -1.5
- Kazuma Okamoto Over 1.5 total bases
- Dylan Cease Over 7.5 strikeouts
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Blue Jays vs A's home run pick: Kazuma Okamoto (+325)
I’m sticking with Okamoto for today’s home run pick as the matchup is too good to ignore.
Okamoto has hit a team-leading eight home runs vs. left-handed pitching — twice as many as anyone else on the Blue Jays.
He’s also hit eight of his 28 dingers vs. the slider, which Lopez throws more than one-third of the time.
- Best bets: 9-10, -2.47 units
- SGPs: 0-1, -1.00 units
Blue Jays vs A's odds
- Moneyline: Toronto -210 | A's +170
- Run line: Toronto -1.5 (-115) | A's +1.5 (-105)
- Over/Under: Over 8 (-120) | Under 8 (+100)
Blue Jays vs A's trend
The Athletics have only covered the run line in 18 of their last 50 home games for -18.90 units and a -31% ROI. Find more MLB betting trends for Blue Jays vs. A's.
How to watch Blue Jays vs A's and game info
| Location | Sutter Health Park, Sacramento, CA |
| Date | Sunday, Sept. 6, 2026 |
| First pitch | 10:05 p.m. ET |
| TV | Sportsnet |
| Blue Jays starting pitcher | Dylan Cease (10-5, 2.25 ERA) |
| A's starting pitcher | Jacob Lopez (6-4, 4.71 ERA) |
Blue Jays vs A's latest injuries
Blue Jays vs A's weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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